J 2012

Tris(phosphonomethyl) Cyclen Derivatives: Synthesis, Acid-Base Properties and Complexation Studies with Cu2+ and Zn2+ Ions

LIMA, Luis M.P., Catarina V. ESTEVES, Rita DELGADO, Petr HERMANN, Jan KOTEK et. al.

Basic information

Original name

Tris(phosphonomethyl) Cyclen Derivatives: Synthesis, Acid-Base Properties and Complexation Studies with Cu2+ and Zn2+ Ions

Authors

LIMA, Luis M.P. (620 Portugal), Catarina V. ESTEVES (620 Portugal), Rita DELGADO (620 Portugal), Petr HERMANN (203 Czech Republic, guarantor), Jan KOTEK (203 Czech Republic), Romana ŠEVČÍKOVÁ (203 Czech Republic, belonging to the institution) and Přemysl LUBAL (203 Czech Republic, belonging to the institution)

Edition

Eur. J. Inorg. Chem. WEINHEIM, Wiley-VCH Verlag GMBH, 2012, 1434-1948

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

10402 Inorganic and nuclear chemistry

Country of publisher

United Kingdom of Great Britain and Northern Ireland

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

Impact factor

Impact factor: 3.120

RIV identification code

RIV/00216224:14740/12:00060067

Organization unit

Central European Institute of Technology

DOI

UT WoS

000303987800008

Keywords in English

macrocyclic ligands; copper; thermodynamics; kinetics; phosphonate complexes

Tags

Tags

International impact, Reviewed
Změněno: 7/4/2013 07:54, Olga Křížová

Abstract

V originále

Three compounds that are based on cyclen and contain three methylphosphonate pendant arms ? (1,4,7,10-tetraazacyclododecane-1,4,7-triyl)tris(methylene)triphosphonic acid (H6do3p), 3-{4,7,10-tris[(dihydroxyphosphoryl)methyl]-1,4,7,10-tetraazacyclododecan-1-yl}propanoic acid (H7do3p1pr) and [10-(3-hydroxypropyl)-1,4,7,10-tetraazacyclododecane-1,4,7-triyl]tris(methylene)triphosphonic acid (H6do3p1ol) ? were synthesized and characterized. X-ray crystal structures were determined for H6do3p and for the complex [Cu(H2O)6]2+[Cu(H2O)(H4dotp)]2 of a related ligand H8dotp [H8dotp = (1,4,7,10-tetraazacyclododecane-1,4,7,10-tetrayl)tetrakis(methylene)tetraphosphonic acid]. They show the copper(II) centre coordinated only to the four amines of the macrocycle and one water molecule in the apical position. The acidbase properties of the three compounds were studied in aqueous solution by potentiometry and 31P NMR spectroscopy. All ligands exhibit very high basicity and their protonation schemes are dominated by proton relocations between the basic sites and intramolecular hydrogen bonding. The thermodynamic stability constants for complexes of the three ligands with Cu2+ and Zn2+ metal ions were determined by potentiometry and exhibit very high values for the complexes of Cu2+. UV/Vis spectroscopy was used to assess the acid-assisted dissociation of the Cu2+ complexes and showed that the dissociation rates are faster than for the corresponding complex of H8dotp, whereas the [Cu(do3p1ol)]4 complex is the most inert one in this series.

Links

ED1.1.00/02.0068, research and development project
Name: CEITEC - central european institute of technology
LC06035, research and development project
Name: Centrum biofyzikální chemie, bioelektrochemie a bioanalýzy. Nové nástroje pro genomiku, proteomiku a biomedicínu.
Investor: Ministry of Education, Youth and Sports of the CR, Centre of Biophysical Chemistry, Bioelectrochemistry and Bioanalysis. New Tools for Genomics, Proteomics and Biomedicine
ME09065, research and development project
Name: Výzkum nových detekčních systémů na bázi senzorových polí pro použití ve speciační analýze
Investor: Ministry of Education, Youth and Sports of the CR, Research of new detection systems based on sensor arrays for application in speciation analysis, Research and Development Programme KONTAKT (ME)