RÉDOVÁ, Martina, Marek SVOBODA and Ondřej SLABÝ. MicroRNAs and their target gene networks in renal cell carcinoma. Biochem Biophys Res Commun. San Diego: Elsevier Science, 2011, vol. 405, No 2, p. 153-156. ISSN 0006-291X. Available from: https://dx.doi.org/10.1016/j.bbrc.2011.01.019. |
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@article{984074, author = {Rédová, Martina and Svoboda, Marek and Slabý, Ondřej}, article_location = {San Diego}, article_number = {2}, doi = {http://dx.doi.org/10.1016/j.bbrc.2011.01.019}, keywords = {MicroRNA; Renal cell carcinoma; Hypoxia; Epithelial-mesenchymal transition; Proliferation; Apoptosis}, language = {eng}, issn = {0006-291X}, journal = {Biochem Biophys Res Commun}, title = {MicroRNAs and their target gene networks in renal cell carcinoma}, url = {http://www.sciencedirect.com/science/article/pii/S0006291X11000386}, volume = {405}, year = {2011} }
TY - JOUR ID - 984074 AU - Rédová, Martina - Svoboda, Marek - Slabý, Ondřej PY - 2011 TI - MicroRNAs and their target gene networks in renal cell carcinoma JF - Biochem Biophys Res Commun VL - 405 IS - 2 SP - 153-156 EP - 153-156 PB - Elsevier Science SN - 0006291X KW - MicroRNA KW - Renal cell carcinoma KW - Hypoxia KW - Epithelial-mesenchymal transition KW - Proliferation KW - Apoptosis UR - http://www.sciencedirect.com/science/article/pii/S0006291X11000386 L2 - http://www.sciencedirect.com/science/article/pii/S0006291X11000386 N2 - MiRNAs are related to the processes of cell proliferation, apoptosis, angiogenesis, invasion, and metastasis in RCC. MiRNAs expression profiles are associated with several RCC-specific genetic alterations. It has been well documented that several miRNAs are downstream effector molecules of the HIF-induced hypoxia response. MiR-200 family is linked to epithelial-mesenchymal transition which is one of the most significant pathogenetic mechanism in RCC. Mechanistic studies in RCC have provided the rationale of using miRNAs as potential therapeutic targets. ER -
RÉDOVÁ, Martina, Marek SVOBODA and Ondřej SLABÝ. MicroRNAs and their target gene networks in renal cell carcinoma. \textit{Biochem Biophys Res Commun}. San Diego: Elsevier Science, 2011, vol.~405, No~2, p.~153-156. ISSN~0006-291X. Available from: https://dx.doi.org/10.1016/j.bbrc.2011.01.019.
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