J 2012

The role of voxel-based morphometry in the detection of cortical dysplasia within the temporal pole in patients with intractable mesial temporal lobe epilepsy

PAIL, Martin, Radek MAREČEK, Markéta HERMANOVÁ, Bronislava SLANÁ, Ivana TYRLÍKOVÁ et. al.

Basic information

Original name

The role of voxel-based morphometry in the detection of cortical dysplasia within the temporal pole in patients with intractable mesial temporal lobe epilepsy

Authors

PAIL, Martin (203 Czech Republic, belonging to the institution), Radek MAREČEK (203 Czech Republic, belonging to the institution), Markéta HERMANOVÁ (203 Czech Republic, belonging to the institution), Bronislava SLANÁ (203 Czech Republic, belonging to the institution), Ivana TYRLÍKOVÁ (203 Czech Republic, belonging to the institution), Robert KUBA (203 Czech Republic, belonging to the institution) and Milan BRÁZDIL (203 Czech Republic, guarantor, belonging to the institution)

Edition

Epilepsia, Hoboken (NJ, USA), WILEY-BLACKWELL, 2012, 0013-9580

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30000 3. Medical and Health Sciences

Country of publisher

United States of America

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

Impact factor

Impact factor: 3.909

RIV identification code

RIV/00216224:14740/12:00060088

Organization unit

Central European Institute of Technology

DOI

UT WoS

000304715900012

Keywords in English

Hippocampal sclerosis; Malformations of cortical development; Focal cortical dysplasias; Mesial temporal lobe epilepsy; Voxel-based morphometry; Temporal pole

Tags

Tags

International impact, Reviewed
Změněno: 20/8/2012 09:06, Olga Křížová

Abstract

V originále

Purpose: To determine whether voxel-based morphometry (VBM) might contribute to the detection of cortical dysplasia within the temporal pole in patients with mesial temporal lobe epilepsy and hippocampal sclerosis (MTLE/ HS). Key Findings: Histopathologic examination revealed cortical dysplasia within the temporal pole in 11 patients. Significance: We found that VBM made a superior contribution to the detection of temporopolar structural malformations (cortical dysplasia) compared to visual inspection. The agreement with postoperative histopathologic proof was clearly significant for VBM results and nonsignificant for visual inspection.

Links

ED1.1.00/02.0068, research and development project
Name: CEITEC - central european institute of technology
MSM0021622404, plan (intention)
Name: Vnitřní organizace a neurobiologické mechanismy funkčních systémů CNS
Investor: Ministry of Education, Youth and Sports of the CR, The internal organisation and neurobiological mechanisms of functional CNS systems under normal and pathological conditions.