RÉDOVÁ, Martina, Alexandr POPRACH, Jana NEKVINDOVÁ, Robert ILIEV, Lenka RADOVÁ, Radek LAKOMÝ, Marek SVOBODA, Rostislav VYZULA and Ondřej SLABÝ. Circulating miR-378 and miR-451 in serum are potential biomarkers for renal cell carcinoma. Journal of Translational Medicine. London: Biomed Central, 2012, vol. 10, March, p. "nestránkováno", 8 pp. ISSN 1479-5876. Available from: https://dx.doi.org/10.1186/1479-5876-10-55.
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Basic information
Original name Circulating miR-378 and miR-451 in serum are potential biomarkers for renal cell carcinoma
Authors RÉDOVÁ, Martina (203 Czech Republic, belonging to the institution), Alexandr POPRACH (203 Czech Republic), Jana NEKVINDOVÁ (203 Czech Republic), Robert ILIEV (203 Czech Republic), Lenka RADOVÁ (203 Czech Republic), Radek LAKOMÝ (203 Czech Republic), Marek SVOBODA (203 Czech Republic, belonging to the institution), Rostislav VYZULA (203 Czech Republic) and Ondřej SLABÝ (203 Czech Republic, guarantor, belonging to the institution).
Edition Journal of Translational Medicine, London, Biomed Central, 2012, 1479-5876.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30200 3.2 Clinical medicine
Country of publisher United Kingdom of Great Britain and Northern Ireland
Confidentiality degree is not subject to a state or trade secret
WWW URL
Impact factor Impact factor: 3.459
RIV identification code RIV/00216224:14740/12:00060118
Organization unit Central European Institute of Technology
Doi http://dx.doi.org/10.1186/1479-5876-10-55
UT WoS 000303352600001
Keywords in English Renal cell carcinoma; MicroRNA; Serum; Biomarker
Tags ok, rivok
Tags International impact, Reviewed
Changed by Changed by: Olga Křížová, učo 56639. Changed: 9/4/2013 23:24.
Abstract
There is no standard serum biomarker used for diagnosis or early detection of recurrence for renal cell carcinoma (RCC) patients. MicroRNAs (miRNAs) are abundant and highly stable in blood serum, and have been recently described as powerful circulating biomarkers in a wide range of solid cancers. Our aim was to identify miRNA signature that can distinguish the blood serum of RCC patients and matched healthy controls and validate identified miRNAs as potential biomarkers for RCC.
Links
ED1.1.00/02.0068, research and development projectName: CEITEC - central european institute of technology
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