Circulating miR-378 and miR-451 in serum are potential
biomarkers for renal cell carcinoma

J 2012

Circulating miR-378 and miR-451 in serum are potential biomarkers for renal cell carcinoma

RÉDOVÁ, Martina, Alexandr POPRACH, Jana NEKVINDOVÁ, Robert ILIEV, Lenka RADOVÁ et. al.

Basic information

Original name

Circulating miR-378 and miR-451 in serum are potential biomarkers for renal cell carcinoma

Authors

RÉDOVÁ, Martina (203 Czech Republic, belonging to the institution), Alexandr POPRACH (203 Czech Republic), Jana NEKVINDOVÁ (203 Czech Republic), Robert ILIEV (203 Czech Republic), Lenka RADOVÁ (203 Czech Republic), Radek LAKOMÝ (203 Czech Republic), Marek SVOBODA (203 Czech Republic, belonging to the institution), Rostislav VYZULA (203 Czech Republic) and Ondřej SLABÝ (203 Czech Republic, guarantor, belonging to the institution)

Edition

Journal of Translational Medicine, London, Biomed Central, 2012, 1479-5876

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30200 3.2 Clinical medicine

Country of publisher

United Kingdom of Great Britain and Northern Ireland

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 3.459

RIV identification code

RIV/00216224:14740/12:00060118

Organization unit

Central European Institute of Technology

DOI

http://dx.doi.org/10.1186/1479-5876-10-55

UT WoS

000303352600001

Keywords in English

Renal cell carcinoma; MicroRNA; Serum; Biomarker

Abstract

V originále

There is no standard serum biomarker used for diagnosis or early detection of recurrence for renal cell carcinoma (RCC) patients. MicroRNAs (miRNAs) are abundant and highly stable in blood serum, and have been recently described as powerful circulating biomarkers in a wide range of solid cancers. Our aim was to identify miRNA signature that can distinguish the blood serum of RCC patients and matched healthy controls and validate identified miRNAs as potential biomarkers for RCC.

Links

ED1.1.00/02.0068, research and development project

Name: CEITEC - central european institute of technology

Citovat

RÉDOVÁ, Martina, Alexandr POPRACH, Jana NEKVINDOVÁ, Robert ILIEV, Lenka RADOVÁ, Radek LAKOMÝ, Marek SVOBODA, Rostislav VYZULA and Ondřej SLABÝ. Circulating miR-378 and miR-451 in serum are potential biomarkers for renal cell carcinoma. Journal of Translational Medicine. London: Biomed Central, 2012, vol. 10, March, p. "nestránkováno", 8 pp. ISSN 1479-5876. Available from: https://dx.doi.org/10.1186/1479-5876-10-55.

@article{984202,
   author = {Rédová, Martina and Poprach, Alexandr and Nekvindová, Jana and Iliev, Robert and Radová, Lenka and Lakomý, Radek and Svoboda, Marek and Vyzula, Rostislav and Slabý, Ondřej},
   article_location = {London},
   article_number = {March},
   doi = {http://dx.doi.org/10.1186/1479-5876-10-55},
   keywords = {Renal cell carcinoma; MicroRNA; Serum; Biomarker},
   language = {eng},
   issn = {1479-5876},
   journal = {Journal of Translational Medicine},
   title = {Circulating miR-378 and miR-451 in serum are potential biomarkers for renal cell carcinoma},
   url = {http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3340316/?tool=pubmed},
   volume = {10},
   year = {2012}
}

TY  - JOUR
ID  - 984202
AU  - Rédová, Martina - Poprach, Alexandr - Nekvindová, Jana - Iliev, Robert - Radová, Lenka - Lakomý, Radek - Svoboda, Marek - Vyzula, Rostislav - Slabý, Ondřej
PY  - 2012
TI  - Circulating miR-378 and miR-451 in serum are potential biomarkers for renal cell carcinoma
JF  - Journal of Translational Medicine
VL  - 10
IS  - March
SP  - "nestránkováno"
EP  - "nestránkováno"
PB  - Biomed Central
SN  - 14795876
KW  - Renal cell carcinoma
KW  - MicroRNA
KW  - Serum
KW  - Biomarker
UR  - http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3340316/?tool=pubmed
L2  - http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3340316/?tool=pubmed
N2  - There is no standard serum biomarker used for diagnosis or early detection of recurrence for renal cell carcinoma (RCC) patients. MicroRNAs (miRNAs) are abundant and highly stable in blood serum, and have been recently described as powerful circulating biomarkers in a wide range of solid cancers. Our aim was to identify miRNA signature that can distinguish the blood serum of RCC patients and matched healthy controls and validate identified miRNAs as potential biomarkers for RCC.
ER  -

RÉDOVÁ, Martina, Alexandr POPRACH, Jana NEKVINDOVÁ, Robert ILIEV, Lenka RADOVÁ, Radek LAKOMÝ, Marek SVOBODA, Rostislav VYZULA and Ondřej SLABÝ. Circulating miR-378 and miR-451 in serum are potential biomarkers for renal cell carcinoma. \textit{Journal of Translational Medicine}. London: Biomed Central, 2012, vol.~10, March, p.~''nestránkováno'', 8 pp. ISSN~1479-5876. Available from: https://dx.doi.org/10.1186/1479-5876-10-55.

Detailed Information on Publication Record