QUANTUM DOTS AND THEIR INTERACTIONS WITH BIOMOLECULES

D 2012

QUANTUM DOTS AND THEIR INTERACTIONS WITH BIOMOLECULES

ŠOBROVÁ, Pavlína, Markéta RYVOLOVÁ, Libor JANŮ, Vojtěch ADAM, Libuše TRNKOVÁ et. al.

Basic information

Original name

QUANTUM DOTS AND THEIR INTERACTIONS WITH BIOMOLECULES

Authors

ŠOBROVÁ, Pavlína (203 Czech Republic), Markéta RYVOLOVÁ (203 Czech Republic), Libor JANŮ (203 Czech Republic), Vojtěch ADAM (203 Czech Republic), Libuše TRNKOVÁ (203 Czech Republic, belonging to the institution), Jaromír HUBÁLEK (203 Czech Republic) and René KIZEK (203 Czech Republic, guarantor)

Edition

Brno, XII. Pracovní setkání fyzikálních chemiků a elektrochemiků. Sborník příspěvků. p. 237-238, 2 pp. 2012

Publisher

Mendelova univerzita v Brně

Other information

Language

English

Type of outcome

Stať ve sborníku

Field of Study

10600 1.6 Biological sciences

Country of publisher

Czech Republic

Confidentiality degree

není předmětem státního či obchodního tajemství

Publication form

printed version "print"

RIV identification code

RIV/00216224:14310/12:00060130

Organization unit

Faculty of Science

ISBN

978-80-7375-618-5

Keywords in English

quantum dots;oligonucleotides;differential pulse voltammetry;prion protein

Abstract

V originále

Semiconductor quantum dots (QDs) coated with thioalkyl acid ligands are often used as probes and reporters for nucleic acid sensing, or protein sensing using aptamers, and are also potential vectors for gene delivery. In such applications, the interactions that potentially lead to the adsorption of oligonucleotides onto the surface of colloidal QDs are an important consideration. The interaction between Beta-sheet breaker prion protein and CdTe quantum dots (QDs) was studied by differential pulse voltammetry connected with adsorptive transfer stripping technique. Results showed that the electrochemical signals of prion protein were strongly quenched by CdTe QDs. This phenomenon can be considered as a first step of suggesting of a biosensor for determination of prions in real samples without a sample pre-treatment.

Citovat

ŠOBROVÁ, Pavlína, Markéta RYVOLOVÁ, Libor JANŮ, Vojtěch ADAM, Libuše TRNKOVÁ, Jaromír HUBÁLEK and René KIZEK. QUANTUM DOTS AND THEIR INTERACTIONS WITH BIOMOLECULES. In XII. Pracovní setkání fyzikálních chemiků a elektrochemiků. Sborník příspěvků. Brno: Mendelova univerzita v Brně, 2012, p. 237-238. ISBN 978-80-7375-618-5.

@inproceedings{984227,
   author = {Šobrová, Pavlína and Ryvolová, Markéta and Janů, Libor and Adam, Vojtěch and Trnková, Libuše and Hubálek, Jaromír and Kizek, René},
   address = {Brno},
   booktitle = {XII. Pracovní setkání fyzikálních chemiků a elektrochemiků. Sborník příspěvků.},
   keywords = {quantum dots;oligonucleotides;differential pulse voltammetry;prion protein},
   howpublished = {tištěná verze "print"},
   language = {eng},
   location = {Brno},
   isbn = {978-80-7375-618-5},
   pages = {237-238},
   publisher = {Mendelova univerzita v Brně},
   title = {QUANTUM DOTS AND THEIR INTERACTIONS WITH BIOMOLECULES},
   year = {2012}
}

TY  - JOUR
ID  - 984227
AU  - Šobrová, Pavlína - Ryvolová, Markéta - Janů, Libor - Adam, Vojtěch - Trnková, Libuše - Hubálek, Jaromír - Kizek, René
PY  - 2012
TI  - QUANTUM DOTS AND THEIR INTERACTIONS WITH BIOMOLECULES
PB  - Mendelova univerzita v Brně
CY  - Brno
SN  - 9788073756185
KW  - quantum dots;oligonucleotides;differential pulse voltammetry;prion protein
N2  - Semiconductor quantum dots (QDs) coated with thioalkyl acid ligands are often used as probes and reporters for nucleic acid sensing, or protein sensing using aptamers, and are also potential vectors for gene delivery. In such applications, the interactions that potentially lead to the adsorption of oligonucleotides onto the surface of colloidal QDs are an important consideration. The interaction between Beta-sheet breaker prion protein and CdTe quantum dots (QDs) was studied by differential pulse voltammetry connected with adsorptive transfer stripping technique. Results showed that the electrochemical signals of prion protein were strongly quenched by CdTe QDs. This phenomenon can be considered as a first step of suggesting of a biosensor for determination of prions in real samples without a sample pre-treatment.
ER  -

ŠOBROVÁ, Pavlína, Markéta RYVOLOVÁ, Libor JANŮ, Vojtěch ADAM, Libuše TRNKOVÁ, Jaromír HUBÁLEK and René KIZEK. QUANTUM DOTS AND THEIR INTERACTIONS WITH BIOMOLECULES. In \textit{XII. Pracovní setkání fyzikálních chemiků a elektrochemiků. Sborník příspěvků.}. Brno: Mendelova univerzita v Brně, 2012, p.~237-238. ISBN~978-80-7375-618-5.

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