Expression Levels of Transcribed Ultraconserved Regions uc.73
and uc.388 Are Altered in Colorectal Cancer

J 2012

Expression Levels of Transcribed Ultraconserved Regions uc.73 and uc.388 Are Altered in Colorectal Cancer

ŠÁNA, Jiří, Simona HANKEOVÁ, Marek SVOBODA, Igor KISS, Rostislav VYZULA et. al.

Basic information

Original name

Expression Levels of Transcribed Ultraconserved Regions uc.73 and uc.388 Are Altered in Colorectal Cancer

Authors

ŠÁNA, Jiří (203 Czech Republic, belonging to the institution), Simona HANKEOVÁ (203 Czech Republic), Marek SVOBODA (203 Czech Republic), Igor KISS (203 Czech Republic), Rostislav VYZULA (203 Czech Republic) and Ondřej SLABÝ (203 Czech Republic, guarantor, belonging to the institution)

Edition

Oncology, Basel, Karger, 2012, 0030-2414

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30200 3.2 Clinical medicine

Country of publisher

Switzerland

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 2.165

RIV identification code

RIV/00216224:14740/12:00060135

Organization unit

Central European Institute of Technology

DOI

http://dx.doi.org/10.1159/000336479

UT WoS

000301774000007

Keywords in English

Colorectal cancer; Non-coding RNAs; Transcribed ultraconserved regions; uc.73; uc.388

Abstract

V originále

The development of colorectal cancer (CRC) is characterized by multiple genetic alterations. Transcribed ultraconserved regions (T-UCRs) are a subset of 481 sequenc es longer than 200 bp, which are absolutely conserved between orthologous regions of human, rat and mouse genomes, and are actively transcribed. It has recently been proven in cancer systems that differentially expressed T-UCRs could alter the functional characteristics of malignant cells. Genome-wide profiling revealed that T-UCRs have distinct signatures in human leukemia and carcinoma.

Links

ED1.1.00/02.0068, research and development project

Name: CEITEC - central european institute of technology

Citovat

ŠÁNA, Jiří, Simona HANKEOVÁ, Marek SVOBODA, Igor KISS, Rostislav VYZULA and Ondřej SLABÝ. Expression Levels of Transcribed Ultraconserved Regions uc.73 and uc.388 Are Altered in Colorectal Cancer. Oncology. Basel: Karger, 2012, vol. 82, No 2, p. 114-118. ISSN 0030-2414. Available from: https://dx.doi.org/10.1159/000336479.

@article{984236,
   author = {Šána, Jiří and Hankeová, Simona and Svoboda, Marek and Kiss, Igor and Vyzula, Rostislav and Slabý, Ondřej},
   article_location = {Basel},
   article_number = {2},
   doi = {http://dx.doi.org/10.1159/000336479},
   keywords = {Colorectal cancer; Non-coding RNAs; Transcribed ultraconserved regions; uc.73; uc.388},
   language = {eng},
   issn = {0030-2414},
   journal = {Oncology},
   title = {Expression Levels of Transcribed Ultraconserved Regions uc.73 and uc.388 Are Altered in Colorectal Cancer},
   url = {http://www.karger.com/Article/Fulltext/336479},
   volume = {82},
   year = {2012}
}

TY  - JOUR
ID  - 984236
AU  - Šána, Jiří - Hankeová, Simona - Svoboda, Marek - Kiss, Igor - Vyzula, Rostislav - Slabý, Ondřej
PY  - 2012
TI  - Expression Levels of Transcribed Ultraconserved Regions uc.73 and uc.388 Are Altered in Colorectal Cancer
JF  - Oncology
VL  - 82
IS  - 2
SP  - 114-118
EP  - 114-118
PB  - Karger
SN  - 00302414
KW  - Colorectal cancer
KW  - Non-coding RNAs
KW  - Transcribed ultraconserved regions
KW  - uc.73
KW  - uc.388
UR  - http://www.karger.com/Article/Fulltext/336479
L2  - http://www.karger.com/Article/Fulltext/336479
N2  - The development of colorectal cancer (CRC) is characterized by multiple genetic alterations. Transcribed ultraconserved regions (T-UCRs) are a subset of 481 sequenc es longer than 200 bp, which are absolutely conserved between orthologous regions of human, rat and mouse genomes, and are actively transcribed. It has recently been proven in cancer systems that differentially expressed T-UCRs could alter the functional characteristics of malignant cells. Genome-wide profiling revealed that T-UCRs have distinct signatures in human leukemia and carcinoma.
ER  -

ŠÁNA, Jiří, Simona HANKEOVÁ, Marek SVOBODA, Igor KISS, Rostislav VYZULA and Ondřej SLABÝ. Expression Levels of Transcribed Ultraconserved Regions uc.73 and uc.388 Are Altered in Colorectal Cancer. \textit{Oncology}. Basel: Karger, 2012, vol.~82, No~2, p.~114-118. ISSN~0030-2414. Available from: https://dx.doi.org/10.1159/000336479.

Detailed Information on Publication Record