ZAMBO, Iva, Markéta HERMANOVÁ, Dagmar ADÁMKOVÁ KRÁKOROVÁ, Peter MÚDRY, Karel ZITTERBART, Michal KÝR, Karel VESELÝ, Jaroslav ŠTĚRBA and Renata VESELSKÁ. Nestin expression in high-grade osteosarcomas and its clinical significance. Oncology Reports. Athens, Greece: Spandidos Publications Ltd., 2012, vol. 27, No 5, p. 1592-1598. ISSN 1021-335X. Available from: https://dx.doi.org/10.3892/or.2012.1687.
Other formats:   BibTeX LaTeX RIS
Basic information
Original name Nestin expression in high-grade osteosarcomas and its clinical significance
Authors ZAMBO, Iva (203 Czech Republic, guarantor, belonging to the institution), Markéta HERMANOVÁ (203 Czech Republic, belonging to the institution), Dagmar ADÁMKOVÁ KRÁKOROVÁ (203 Czech Republic, belonging to the institution), Peter MÚDRY (203 Czech Republic, belonging to the institution), Karel ZITTERBART (203 Czech Republic, belonging to the institution), Michal KÝR (203 Czech Republic, belonging to the institution), Karel VESELÝ (203 Czech Republic, belonging to the institution), Jaroslav ŠTĚRBA (203 Czech Republic, belonging to the institution) and Renata VESELSKÁ (203 Czech Republic, belonging to the institution).
Edition Oncology Reports, Athens, Greece, Spandidos Publications Ltd. 2012, 1021-335X.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30200 3.2 Clinical medicine
Country of publisher Greece
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 2.297
RIV identification code RIV/00216224:14110/12:00060164
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.3892/or.2012.1687
UT WoS 000302202600044
Keywords (in Czech) osteosarkom; nestin; prognóza; imunohistochemie; imunofluorescence
Keywords in English osteosarcoma; nestin; prognosis; immunohistochemistry; immunofluorescence
Tags International impact, Reviewed
Changed by Changed by: Soňa Böhmová, učo 232884. Changed: 22/4/2013 14:32.
Abstract
Using immunohistochemistry and immunofluorescence, we evaluated nestin expression in tumor tissue samples from 45 patients with high-grade osteosarcomas. High levels of nestin expression detected by immunofluorescence were associated with worse clinical outcomes. However, high levels of nestin expression detected by immunohistochemistry trended towards shorter OS and EFS but did not reach statistical significance. Nestin does not seem to represent a powerful prognostic marker for patients with high-grade osteosarcomas.
Links
MSM0021622415, plan (intention)Name: Molekulární podstata buněčných a tkáňových regulací
Investor: Ministry of Education, Youth and Sports of the CR, Molecular basis of cell and tissue regulations
PrintDisplayed: 21/8/2024 20:10