Detailed Information on Publication Record
2012
MicroRNAs and Colorectal Cancer
SLABÝ, Ondřej, Marek SVOBODA and Rostislav VYZULABasic information
Original name
MicroRNAs and Colorectal Cancer
Authors
SLABÝ, Ondřej (203 Czech Republic, guarantor, belonging to the institution), Marek SVOBODA (203 Czech Republic) and Rostislav VYZULA (203 Czech Republic)
Edition
New York, MicroRNAs in Solid Cancer: From Biomarkers to Therapeutic Targets, p. 65-80, 16 pp. 2012
Publisher
Nova Science Publishers, Inc.
Other information
Language
English
Type of outcome
Kapitola resp. kapitoly v odborné knize
Field of Study
30200 3.2 Clinical medicine
Country of publisher
United States of America
Confidentiality degree
není předmětem státního či obchodního tajemství
Publication form
printed version "print"
RIV identification code
RIV/00216224:14740/12:00060171
Organization unit
Central European Institute of Technology
ISBN
978-1-61324-514-9
Keywords in English
microRNAs; colorectal cancer
Tags
International impact, Reviewed
Změněno: 13/3/2013 13:38, Olga Křížová
Abstract
V originále
Colorectal cancer (CRC) represents one of the most frequent causes of death for cancer. CRC has been recently defined as the third most common cancer. Polymorphisms within microRNAs binding regions have been described as new risk factors for CRC. Several genome-wide profiling studies have identified miRNAs deregulated in CRC tissue. Furthermore, number of experimental studies on these miRNAs revealed insight into miRNA-mediated, regulatory links to well-known oncogenic and tumor suppressor signaling pathways. Several investigations have also described the ability of specific miRNA expression profiles to predict prognosis and therapy response, and potential of selected miRNAs as therapeutical targets in CRC patients.
Links
| ED1.1.00/02.0068, research and development project |
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