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@inbook{984809,
author = {Slabý, Ondřej and Svoboda, Marek and Vyzula, Rostislav},
address = {New York},
booktitle = {MicroRNAs in Solid Cancer: From Biomarkers to Therapeutic Targets},
editor = {Ondrej Slaby},
keywords = {microRNAs; colorectal cancer},
howpublished = {tištěná verze "print"},
language = {eng},
location = {New York},
isbn = {978-1-61324-514-9},
pages = {65-80},
publisher = {Nova Science Publishers, Inc.},
title = {MicroRNAs and Colorectal Cancer},
year = {2012}
}
TY - CHAP
ID - 984809
AU - Slabý, Ondřej - Svoboda, Marek - Vyzula, Rostislav
PY - 2012
TI - MicroRNAs and Colorectal Cancer
VL - Neuveden
PB - Nova Science Publishers, Inc.
CY - New York
SN - 9781613245149
KW - microRNAs
KW - colorectal cancer
N2 - Colorectal cancer (CRC) represents one of the most frequent causes of death for cancer. CRC has been recently defined as the third most common cancer. Polymorphisms within microRNAs binding regions have been described as new risk factors for CRC. Several genome-wide profiling studies have identified miRNAs deregulated in CRC tissue. Furthermore, number of experimental studies on these miRNAs revealed insight into miRNA-mediated, regulatory links to well-known oncogenic and tumor suppressor signaling pathways. Several investigations have also described the ability of specific miRNA expression profiles to predict prognosis and therapy response, and potential of selected miRNAs as therapeutical targets in CRC patients.
ER -
SLABÝ, Ondřej, Marek SVOBODA and Rostislav VYZULA. MicroRNAs and Colorectal Cancer. In Ondrej Slaby. \textit{MicroRNAs in Solid Cancer: From Biomarkers to Therapeutic Targets}. New York: Nova Science Publishers, Inc. p.~65-80. ISBN~978-1-61324-514-9. 2012.
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