MicroRNAs and Breast Cancer

RÉDOVÁ, Martina, Marek SVOBODA and Rostislav VYZULA. MicroRNAs and Breast Cancer. In Ondrej Slaby. MicroRNAs in Solid Cancer: From Biomarkers to Therapeutic Targets. New York: Nova Science Publishers, Inc., 2012, p. 81-94. ISBN 978-1-61324-514-9.

Basic information

Original name

MicroRNAs and Breast Cancer

Authors

RÉDOVÁ, Martina, Marek SVOBODA and Rostislav VYZULA

Edition

New York, MicroRNAs in Solid Cancer: From Biomarkers to Therapeutic Targets, p. 81-94, 14 pp. 2012

Publisher

Nova Science Publishers, Inc.

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Other information

Language

English

Type of outcome

Kapitola resp. kapitoly v odborné knize

Field of Study

30200 3.2 Clinical medicine

Country of publisher

United States of America

Confidentiality degree

není předmětem státního či obchodního tajemství

Publication form

printed version "print"

Organization unit

Central European Institute of Technology

ISBN

978-1-61324-514-9

Keywords in English

microRNAs; breast cancer

Tags

ne MU

Tags

International impact, Reviewed

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Abstract

V originále

Breast cancer is a heterogeneous disease, comprising multiple entities associated with distinctive histological and biological features, clinical presentations and behaviours and responses to therapy. It is the second leading cause of cancer death in women. Despite improvement in treatment over the past few decades, there is an urgent need for development of targeted therapies. MicroRNAs (miRNAs) regulate diverse cellular processes and play an integral role in cancer pathogenesis. Emerging evidences suggest the involvement of altered regulation of miRNAs in the pathogenesis of breast cancer. MiRNAs are therefore thought to be functional as tumor suppressors or oncogenes, and as a consequence not only potential effective biomarkers, but also novel class of therapeutic targets.