RÉDOVÁ, Martina. MicroRNAs and Hepatocellular Carcinoma. In Ondrej Slaby. MicroRNAs in Solid Cancer: From Biomarkers to Therapeutic Targets. New York: Nova Science Publishers, Inc., 2012, p. 129-140. ISBN 978-1-61324-514-9.
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Basic information
Original name MicroRNAs and Hepatocellular Carcinoma
Authors RÉDOVÁ, Martina.
Edition New York, MicroRNAs in Solid Cancer: From Biomarkers to Therapeutic Targets, p. 129-140, 12 pp. 2012.
Publisher Nova Science Publishers, Inc.
Other information
Original language English
Type of outcome Chapter(s) of a specialized book
Field of Study 30200 3.2 Clinical medicine
Country of publisher United States of America
Confidentiality degree is not subject to a state or trade secret
Publication form printed version "print"
Organization unit Central European Institute of Technology
ISBN 978-1-61324-514-9
Keywords in English microRNAs; hepatocellular cancer
Tags ne MU
Tags International impact, Reviewed
Changed by Changed by: Olga Křížová, učo 56639. Changed: 19/3/2013 09:02.
Abstract
Hepatocellular carcinoma (HCC) is the fifth most prevalent cancer in the world and is the third leading cause of cancer-related death. Because of its high fatality rates, the incidence and mortality rates are almost equal. From these reasons, it is necessary to identify powerful biological markers that can be used to screen high-risk patients in order to allow better HCC detection, earlier intervention, and to increase the likelihood of successful treatment. Accumulating evidence has linked the dysregulated miRNA levels to a variety of malignancies, including HCC. Several investigations have also described the ability of specific miRNA expression profiles to predict prognosis, and potential of selected miRNAs as novel therapeutic targets in HCC patients.
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