MicroRNAs and Gastric Cancer

SLABÝ, Ondřej. MicroRNAs and Gastric Cancer. In Ondrej Slaby. MicroRNAs in Solid Cancer: From Biomarkers to Therapeutic Targets. New York: Nova Science Publishers, Inc., 2012, p. 149-160. ISBN 978-1-61324-514-9.

Basic information

Original name

MicroRNAs and Gastric Cancer

Authors

SLABÝ, Ondřej (203 Czech Republic, guarantor, belonging to the institution)

Edition

New York, MicroRNAs in Solid Cancer: From Biomarkers to Therapeutic Targets, p. 149-160, 12 pp. 2012

Publisher

Nova Science Publishers, Inc.

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Other information

Language

English

Type of outcome

Kapitola resp. kapitoly v odborné knize

Field of Study

30200 3.2 Clinical medicine

Country of publisher

United States of America

Confidentiality degree

není předmětem státního či obchodního tajemství

Publication form

printed version "print"

RIV identification code

RIV/00216224:14740/12:00060176

Organization unit

Central European Institute of Technology

ISBN

978-1-61324-514-9

Keywords in English

microRNAs; gastric cancer

Tags

ok, rivok

Tags

International impact, Reviewed

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Abstract

V originále

Gastric cancer is the fourth most common cancer in the world. Polymorphisms within miRNA genes have been described as new risk factors for atrophic gastritis and gastric cancer. A substantial number of miRNAs show differential expression in gastric cancer tissues. Genes coding for these miRNAs have been characterized as novel protooncogenes and tumor-suppressor genes based on findings that these miRNAs control malignant phenotypes of gastric cancer cells and the carcinogenic effect of Helicobacter pylori infection. Several investigations have also described the ability of specific miRNA expression profiles to predict prognosis, and potential of selected miRNAs as therapeutic targets in gastric cancer patients.

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Links

ED1.1.00/02.0068, research and development project

Name: CEITEC - central european institute of technology