ŠÁNA, Jiří, Radek LAKOMÝ, Marian HAJDÚCH and Ondřej SLABÝ. MicroRNAs and Glioblastoma. In Ondrej Slaby. MicroRNAs in Solid Cancer: From Biomarkers to Therapeutic Targets. New York: Nova Science Publishers, Inc., 2012, p. 169-176. ISBN 978-1-61324-514-9.
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Basic information
Original name MicroRNAs and Glioblastoma
Authors ŠÁNA, Jiří, Radek LAKOMÝ, Marian HAJDÚCH and Ondřej SLABÝ.
Edition New York, MicroRNAs in Solid Cancer: From Biomarkers to Therapeutic Targets, p. 169-176, 8 pp. 2012.
Publisher Nova Science Publishers, Inc.
Other information
Original language English
Type of outcome Chapter(s) of a specialized book
Field of Study 30200 3.2 Clinical medicine
Country of publisher United States of America
Confidentiality degree is not subject to a state or trade secret
Publication form printed version "print"
Organization unit Central European Institute of Technology
ISBN 978-1-61324-514-9
Keywords in English microRNAs; glioblastoma
Tags ne MU
Tags International impact, Reviewed
Changed by Changed by: Olga Křížová, učo 56639. Changed: 19/3/2013 09:11.
Abstract
Glioblastoma is the highly malignant brain tumor with very poor prognosis. Despite great progress, current therapeutic approaches are insufficient for total cure of patients afflicted with this malignity. MiRNAs represent promising therapeutic targets in glioblastoma. In this chapter we summarize the current knowledge about miRNAs significance in glioblastoma, with special focus on their involvement in core signaling pathways, their roles in drug resistance and potential clinical implications.
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