HÉŽOVÁ, Renata, Alena KOVAŘÍKOVÁ, Julie BIENERTOVÁ VAŠKŮ, Milana ŠACHLOVÁ, Martina RÉDOVÁ, Anna VAŠKŮ, Marek SVOBODA, Lenka RADOVÁ, Igor KISS, Rostislav VYZULA and Ondřej SLABÝ. Evaluation of SNPs in miR-196-a2, miR-27a and miR-146a as risk factors of colorectal cancer. World Journal of Gastroenterology. Beijing, China: Baishideng, 2012, vol. 18, No 22, p. 2827-2831. ISSN 1007-9327. Available from: https://dx.doi.org/10.3748/wjg.v18.i22.2827. |
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@article{985898, author = {Héžová, Renata and Kovaříková, Alena and Bienertová Vašků, Julie and Šachlová, Milana and Rédová, Martina and Vašků, Anna and Svoboda, Marek and Radová, Lenka and Kiss, Igor and Vyzula, Rostislav and Slabý, Ondřej}, article_location = {Beijing, China}, article_number = {22}, doi = {http://dx.doi.org/10.3748/wjg.v18.i22.2827}, keywords = {Association study; Colorectal cancer; MicroRNA; Single nucleotide polymorphism}, language = {eng}, issn = {1007-9327}, journal = {World Journal of Gastroenterology}, title = {Evaluation of SNPs in miR-196-a2, miR-27a and miR-146a as risk factors of colorectal cancer}, url = {http://www.wjgnet.com/1007-9327/full/v18/i22/2827.htm}, volume = {18}, year = {2012} }
TY - JOUR ID - 985898 AU - Héžová, Renata - Kovaříková, Alena - Bienertová Vašků, Julie - Šachlová, Milana - Rédová, Martina - Vašků, Anna - Svoboda, Marek - Radová, Lenka - Kiss, Igor - Vyzula, Rostislav - Slabý, Ondřej PY - 2012 TI - Evaluation of SNPs in miR-196-a2, miR-27a and miR-146a as risk factors of colorectal cancer JF - World Journal of Gastroenterology VL - 18 IS - 22 SP - 2827-2831 EP - 2827-2831 PB - Baishideng SN - 10079327 KW - Association study KW - Colorectal cancer KW - MicroRNA KW - Single nucleotide polymorphism UR - http://www.wjgnet.com/1007-9327/full/v18/i22/2827.htm L2 - http://www.wjgnet.com/1007-9327/full/v18/i22/2827.htm N2 - In order to investigate the effect of selected single nucleotide polymorphisms (SNPs) in miR-196a2, miR-27a and miR-146a genes in CRC, we performed a case-control study of 197 cases of sporadic CRC and 212 cancer-free controls originating from the Central-European Caucasian population using TaqMan Real-Time polymerase chain reaction and allelic discrimination analysis.The genotype and allele frequencies of SNPs were compared between the cases and the controls. Unfortunately, none of the performed analysis showed any statistically significant results. Our data suggest a lack of association between rs11614913, rs895819 and rs2910164 and colorectal cancer risk in the Central-European Caucasian population, a population with an extremely high incidence of sporadic colorectal cancer. ER -
HÉŽOVÁ, Renata, Alena KOVAŘÍKOVÁ, Julie BIENERTOVÁ VAŠKŮ, Milana ŠACHLOVÁ, Martina RÉDOVÁ, Anna VAŠKŮ, Marek SVOBODA, Lenka RADOVÁ, Igor KISS, Rostislav VYZULA and Ondřej SLABÝ. Evaluation of SNPs in miR-196-a2, miR-27a and miR-146a as risk factors of colorectal cancer. \textit{World Journal of Gastroenterology}. Beijing, China: Baishideng, 2012, vol.~18, No~22, p.~2827-2831. ISSN~1007-9327. Available from: https://dx.doi.org/10.3748/wjg.v18.i22.2827.
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