| DEMO, Gabriel, Veronika PAPOUŠKOVÁ, Hana ŠANDEROVÁ, Lukáš ŽÍDEK and Michaela WIMMEROVÁ. Significant changes between the Xray structure and NMR structure of delta subunit of RNA polymerase (Significant changes between the X-ray structure and NMR structure of delta subunit of RNA polymerase). In Struktura 2012, Cesko-slovenska krystalograficka spolecnost. 2012. ISSN 1211-5894. |
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@proceedings{986112,
author = {Demo, Gabriel and Papoušková, Veronika and Šanderová, Hana and Žídek, Lukáš and Wimmerová, Michaela},
booktitle = {Struktura 2012, Cesko-slovenska krystalograficka spolecnost},
keywords = {delta subunit comparism NMR Xray structure},
language = {cze},
title = {Significant changes between the Xray structure and NMR structure of delta subunit of RNA polymerase},
year = {2012}
}
TY - CONF
ID - 986112
AU - Demo, Gabriel - Papoušková, Veronika - Šanderová, Hana - Žídek, Lukáš - Wimmerová, Michaela
PY - 2012
TI - Significant changes between the Xray structure and NMR structure of delta subunit of RNA polymerase
KW - delta subunit comparism NMR Xray structure
N2 - RNA polymerase is an essential enzyme. RNAP from gram negative bacteria contain two additional subunits. The delta subunit is 173 aminoacids long and comes from Bacillus subtilis. The N terminal domain displays an ordered structure and the C terminal domain appears to be flexible and unstructured. The N terminal domain was solved either with NMR and Xray. The Xray structure showed completely different behaviour in the region corresponding to beta sheets present in NMR structure. In the Xray structure were found nickel ions which may have a significant effect on the folding of the protein. This is a strong proof that some of the proteins can be differently structured in the solution as in the crystalline phase.
ER -
DEMO, Gabriel, Veronika PAPOUŠKOVÁ, Hana ŠANDEROVÁ, Lukáš ŽÍDEK and Michaela WIMMEROVÁ. Significant changes between the Xray structure and NMR structure of delta subunit of RNA polymerase (Significant changes between the X-ray structure and NMR structure of delta subunit of RNA polymerase). In \textit{Struktura 2012, Cesko-slovenska krystalograficka spolecnost}. 2012. ISSN~1211-5894.
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