J 2012

Advances in patch clamp technique: towards higher quality and quantity

BÉBAROVÁ, Markéta

Basic information

Original name

Advances in patch clamp technique: towards higher quality and quantity

Authors

BÉBAROVÁ, Markéta (203 Czech Republic, guarantor, belonging to the institution)

Edition

General physiology and biophysics, GENERAL PHYSIOL AND BIOPHYSICS, 2012, 0231-5882

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30105 Physiology

Country of publisher

Slovakia

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 0.852

RIV identification code

RIV/00216224:14110/12:00060414

Organization unit

Faculty of Medicine

DOI

UT WoS

000305315600002

Keywords in English

Action potential clamp; Dynamic clamp; Cell-type transforming clamp; High-resolution scanning patch clamp; Automated patch clamp

Tags

International impact, Reviewed
Změněno: 17/8/2017 17:40, doc. MUDr. Markéta Bébarová, Ph.D.

Abstract

V originále

The patch clamp technique, developed in late 1970s, started a new period of experimental cardiac electrophysiology enabling measurement of ionic currents on isolated cardiomyocytes down to the level of single channels. Since that time, the technique has been substantially improved by development of several upgraded modifications providing so far unavailable data (e.g. action potential clamp, dynamic clamp, high-resolution scanning patch clamp), or facilitating the patch clamp technique by increasing its efficiency (planar patch clamp, automated patch clamp). The current review summarizes the leading new patch clamp based techniques used in cardiac cellular electrophysiology, their principles and prominent related papers.

Links

MSM0021622402, plan (intention)
Name: Časná diagnostika a léčba kardiovaskulárních chorob
Investor: Ministry of Education, Youth and Sports of the CR, Early diagnostics and treatment of cardiovascular diseases