SOŠKA, Vladimír, Petr DOBŠÁK, Ladislav DUŠEK, Kohji SHIRAI, Jiří JARKOVSKÝ, Marie NOVÁKOVÁ, Petr BRHEL, Jana ŠŤASTNÁ, Lenka FAJKUSOVÁ, Tomáš FREIBERGER and Tomoyuki YAMBE. Cardio-Ankle Vascular Index in Heterozygous Familial Hypercholesterolemia. JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS. TOKYO: JAPAN ATHEROSCLEROSIS SOC, 2012, vol. 19, No 5, p. 453-461. ISSN 1340-3478.
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Basic information
Original name Cardio-Ankle Vascular Index in Heterozygous Familial Hypercholesterolemia
Authors SOŠKA, Vladimír (203 Czech Republic, guarantor, belonging to the institution), Petr DOBŠÁK (203 Czech Republic, belonging to the institution), Ladislav DUŠEK (203 Czech Republic, belonging to the institution), Kohji SHIRAI (392 Japan), Jiří JARKOVSKÝ (203 Czech Republic, belonging to the institution), Marie NOVÁKOVÁ (203 Czech Republic, belonging to the institution), Petr BRHEL (203 Czech Republic, belonging to the institution), Jana ŠŤASTNÁ (203 Czech Republic, belonging to the institution), Lenka FAJKUSOVÁ (203 Czech Republic), Tomáš FREIBERGER (203 Czech Republic) and Tomoyuki YAMBE (392 Japan).
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30201 Cardiac and Cardiovascular systems
Country of publisher Japan
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 2.933
RIV identification code RIV/00216224:14110/12:00064863
Organization unit Faculty of Medicine
UT WoS 000304754500005
Keywords in English Atherosclerosis; Cardio-ankle vascular index; Familial hypercholesterolemia; Statins; Ezetimibe
Tags International impact, Reviewed
Changed by Changed by: Soňa Böhmová, učo 232884. Changed: 22. 4. 2013 18:33.
Aim: The cardio-ankle vascular index (CAVI) is a new non-invasive marker of arterial stiffness and atherosclerosis. The purpose of this study was to compare CAVI in patients with heterozygous familial hypercholesterolemia (FH) and in healthy controls. Methods: 82 FH subjects (27 males, 65 females), aged 53.7 +/- 13.6 years without clinical symptoms of cardiovascular diseases and 359 healthy controls (121 males, 238 females), aged 43.9 +/- 14.9 years, were examined. CAVI was measured using the system VaSera (R) 1500. Results: CAVI in FH patients was significantly higher (8.0 +/- 1.4) than in healthy subjects (7.5 +/- 1.3) p=0.002; however, age, sex and BMI adjusted CAVI did not differ significantly (p=0.061) between the FH group (7.5, CI: 7.3; 7.7) and control group (7.7, CI: 7.6; 7.7). Conclusion: The study showed no significant difference in CAVI between heterozygous FH and healthy controls.
NS10096, research and development projectName: Zvýšení účinnosti rehabilitace vlivem kombinovaného aerobního tréninku doplněného o elektromyostimulaci u nemocných s chronickým srdečním selháním
Investor: Ministry of Health of the CR
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