BÜCHLER, Tomáš, Kateřina SIMONOVÁ, Pavel FENCL, Jiří JARKOVSKÝ and Jitka ABRAHÁMOVÁ. Clinical Outcomes of Patients with Nonseminomatous Germ Cell Tumours and Negative Postchemotherapy Positron Emission Tomography. Cancer Investigation. LONDON: INFORMA HEALTHCARE, 2012, vol. 30, No 6, p. 487-492. ISSN 0735-7907. doi:10.3109/07357907.2012.679347. |
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@article{987427, author = {Büchler, Tomáš and Simonová, Kateřina and Fencl, Pavel and Jarkovský, Jiří and Abrahámová, Jitka}, article_location = {LONDON}, article_number = {6}, doi = {http://dx.doi.org/10.3109/07357907.2012.679347}, keywords = {Positron emission tomography; Germ cell tumour; Testicular cancer; Diagnosis; Relapse}, language = {eng}, issn = {0735-7907}, journal = {Cancer Investigation}, title = {Clinical Outcomes of Patients with Nonseminomatous Germ Cell Tumours and Negative Postchemotherapy Positron Emission Tomography}, volume = {30}, year = {2012} }
TY - JOUR ID - 987427 AU - Büchler, Tomáš - Simonová, Kateřina - Fencl, Pavel - Jarkovský, Jiří - Abrahámová, Jitka PY - 2012 TI - Clinical Outcomes of Patients with Nonseminomatous Germ Cell Tumours and Negative Postchemotherapy Positron Emission Tomography JF - Cancer Investigation VL - 30 IS - 6 SP - 487-492 EP - 487-492 PB - INFORMA HEALTHCARE SN - 07357907 KW - Positron emission tomography KW - Germ cell tumour KW - Testicular cancer KW - Diagnosis KW - Relapse N2 - Univariate and multivariate analyses were carried out to identify factors associated with the failure of 18-fluorodeoxyglucose positron emission tomography (FDG-PET) to correctly predict relapse-free survival in patients with nonseminomatous germ cell tumours. Ninety-three patients with negative postchemotherapy FDG-PET scan were analyzed in the retrospective study. The FDG-PET result was validated by long-term follow-up and, in some patients, by resection of the residual tumour mass. The negative predictive value of FDG-PET was 81.7%. Higher tumour marker levels and nodal stage at diagnosis, presence of residual mass, and teratoma or teratocarcinoma in the primary histology were associated with FDG-PET failure. ER -
BÜCHLER, Tomáš, Kateřina SIMONOVÁ, Pavel FENCL, Jiří JARKOVSKÝ and Jitka ABRAHÁMOVÁ. Clinical Outcomes of Patients with Nonseminomatous Germ Cell Tumours and Negative Postchemotherapy Positron Emission Tomography. \textit{Cancer Investigation}. LONDON: INFORMA HEALTHCARE, 2012, vol.~30, No~6, p.~487-492. ISSN~0735-7907. doi:10.3109/07357907.2012.679347.
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