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@inbook{987445,
author = {Doubek, Michael and Mayer, Jiří},
address = {New York},
booktitle = {Acute Lymphoblastic Leukemia: Etiology, Pathogenesis and Treatments},
editor = {Severo Vecchione, Luigi Tedesco},
keywords = {acute lymphoblastic leukemia; therapy; maintenance},
howpublished = {tištěná verze "print"},
language = {eng},
location = {New York},
isbn = {978-1-61470-872-8},
pages = {197-204},
publisher = {Nova Science Publishers},
title = {Maintenance therapy in Ph negative adult acute lymphoblastic leukemia},
year = {2011}
}
TY - CHAP
ID - 987445
AU - Doubek, Michael - Mayer, Jiří
PY - 2011
TI - Maintenance therapy in Ph negative adult acute lymphoblastic leukemia
VL - Cancer Etiology, Diagnosis and Treatments
PB - Nova Science Publishers
CY - New York
SN - 9781614708728
KW - acute lymphoblastic leukemia
KW - therapy
KW - maintenance
N2 - Maintenance therapy means long-term administration of low-dose chemotherapy or other drugs. With the exception of patients with mature B-cell acute lymphoblastic leukemia (ALL), long-term maintenance therapy, adapted from its successful use in pediatric ALL, is generally given in adult ALL for one to three years, with a backbone of daily 6-mercaptopurine (MP) and weekly methothrexate (MTX). In the chapter we discuss the role of maintenance in adult ALL, the role of intensification of maintenance, maintenance after autologous stem cell transplantation and the role of minimal residual disease evaluation during maintenance.
ER -
DOUBEK, Michael a Jiří MAYER. Maintenance therapy in Ph negative adult acute lymphoblastic leukemia. In Severo Vecchione, Luigi Tedesco. \textit{Acute Lymphoblastic Leukemia: Etiology, Pathogenesis and Treatments}. New York: Nova Science Publishers, 2011, s.~197-204. Cancer Etiology, Diagnosis and Treatments. ISBN~978-1-61470-872-8.
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