Non-coding RNAs in Gastrointestinal Cancer: Novel Biomarkers
and Therapeutic Targets

B 2012

Non-coding RNAs in Gastrointestinal Cancer: Novel Biomarkers and Therapeutic Targets

FALTEJSKOVÁ, Petra a Ondřej SLABÝ

Základní údaje

Originální název

Non-coding RNAs in Gastrointestinal Cancer: Novel Biomarkers and Therapeutic Targets

Název česky

Nekódující RNA u nádorů gastrointestinálního traktu

Autoři

FALTEJSKOVÁ, Petra (203 Česká republika, domácí) a Ondřej SLABÝ (203 Česká republika, garant, domácí)

Vydání

první. Germany, 104 s. 2012

Nakladatel

LAP LAMBERT Academic Publishing

Další údaje

Jazyk

angličtina

Typ výsledku

Odborná kniha

Obor

30200 3.2 Clinical medicine

Stát vydavatele

Německo

Utajení

není předmětem státního či obchodního tajemství

Forma vydání

tištěná verze "print"

Odkazy

URL

Kód RIV

RIV/00216224:14740/12:00064867

Organizační jednotka

Středoevropský technologický institut

ISBN

978-3-659-18971-5

Klíčová slova česky

mikroRNA; nekódující RNA; gastrointestinální nádory; prognóza; predikce; jednonukleotidové polymorfizmy; expresní profilování

Klíčová slova anglicky

microRNAs; non-coding RNAs; gastrointestinal tumours; prognosis; prediction; single nucleotide polymorphisms; expression profiling

Štítky

ok, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 10. 4. 2013 00:52, Olga Křížová

Anotace

V originále

Digestive tumours are the most frequent malignant tumours in the world and the leading cause of a cancer-related death. They are tough to treat once they have formed and many are not found until they have already spread to other parts of the body. Therefore, new biomarkers enabling early diagnosis of asymptomatic disease, accurate differentiation among particular clinical stages and individualization of therapy are sorely needed. With improved methods to explore the transcriptome, different types of non-coding RNAs have been identified. It was proved that these molecules are highly deregulated in cancer tissue and involved in important molecular and biological processes such as differentiation, proliferation, apoptosis, migration or cell cycle. Moreover, detailed analyses revealed that they could serve as new molecular markers useful for cancer classification, prognostic stratification, and drug response prediction. Non-coding RNAs in Gastrointestinal Cancer offers a comprehensive collection of current information about the role of non coding RNAs in gastrointestinal cancer pathogenesis and illustrates, how this knowledge may be useful in medical practice.

Návaznosti

NT13549, projekt VaV

Název: Vytvoření diagnostické sady cirkulujících mikroRNA pro neinvazivní časnou diagnostiku a sledování pacientů s kolorektálním karcinomem

Citovat

FALTEJSKOVÁ, Petra a Ondřej SLABÝ. Non-coding RNAs in Gastrointestinal Cancer: Novel Biomarkers and Therapeutic Targets. první. Germany: LAP LAMBERT Academic Publishing, 2012, 104 s. ISBN 978-3-659-18971-5.

@book{987947,
   author = {Faltejsková, Petra and Slabý, Ondřej},
   address = {Germany},
   edition = {první},
   keywords = {microRNAs; non-coding RNAs; gastrointestinal tumours; prognosis; prediction; single nucleotide polymorphisms; expression profiling},
   howpublished = {tištěná verze "print"},
   language = {eng},
   location = {Germany},
   isbn = {978-3-659-18971-5},
   publisher = {LAP LAMBERT Academic Publishing},
   title = {Non-coding RNAs in Gastrointestinal Cancer: Novel Biomarkers and Therapeutic Targets},
   url = {http://www.amazon.com/Non-coding-RNAs-Gastrointestinal-Cancer-Therapeutic/dp/3659189715},
   year = {2012}
}

TY  - BOOK
ID  - 987947
AU  - Faltejsková, Petra - Slabý, Ondřej
PY  - 2012
TI  - Non-coding RNAs in Gastrointestinal Cancer: Novel Biomarkers and Therapeutic Targets
VL  - Neuveden
PB  - LAP LAMBERT Academic Publishing
CY  - Germany
SN  - 9783659189715
KW  - microRNAs
KW  - non-coding RNAs
KW  - gastrointestinal tumours
KW  - prognosis
KW  - prediction
KW  - single nucleotide polymorphisms
KW  - expression profiling
UR  - http://www.amazon.com/Non-coding-RNAs-Gastrointestinal-Cancer-Therapeutic/dp/3659189715
L2  - http://www.amazon.com/Non-coding-RNAs-Gastrointestinal-Cancer-Therapeutic/dp/3659189715
N2  - Digestive tumours are the most frequent malignant tumours in the world and the leading cause of a cancer-related death. They are tough to treat once they have formed and many are not found until they have already spread to other parts of the body. Therefore, new biomarkers enabling early diagnosis of asymptomatic disease, accurate differentiation among particular clinical stages and individualization of therapy are sorely needed. With improved methods to explore the transcriptome, different types of non-coding RNAs have been identified. It was proved that these molecules are highly deregulated in cancer tissue and involved in important molecular and biological processes such as differentiation, proliferation, apoptosis, migration or cell cycle. Moreover, detailed analyses revealed that they could serve as new molecular markers useful for cancer classification, prognostic stratification, and drug response prediction. Non-coding RNAs in Gastrointestinal Cancer offers a comprehensive collection of current information about the role of non coding RNAs in gastrointestinal cancer pathogenesis and illustrates, how this knowledge may be useful in medical practice.
ER  -

FALTEJSKOVÁ, Petra a Ondřej SLABÝ. \textit{Non-coding RNAs in Gastrointestinal Cancer: Novel Biomarkers and Therapeutic Targets}. první. Germany: LAP LAMBERT Academic Publishing, 2012, 104 s. ISBN~978-3-659-18971-5.

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