Non-coding RNAs in Gastrointestinal Cancer: Novel Biomarkers
and Therapeutic Targets

B 2012

Non-coding RNAs in Gastrointestinal Cancer: Novel Biomarkers and Therapeutic Targets

FALTEJSKOVÁ, Petra and Ondřej SLABÝ

Basic information

Original name

Non-coding RNAs in Gastrointestinal Cancer: Novel Biomarkers and Therapeutic Targets

Name in Czech

Nekódující RNA u nádorů gastrointestinálního traktu

Authors

FALTEJSKOVÁ, Petra (203 Czech Republic, belonging to the institution) and Ondřej SLABÝ (203 Czech Republic, guarantor, belonging to the institution)

Edition

první. Germany, 104 pp. 2012

Publisher

LAP LAMBERT Academic Publishing

Other information

Language

English

Type of outcome

Odborná kniha

Field of Study

30200 3.2 Clinical medicine

Country of publisher

Germany

Confidentiality degree

není předmětem státního či obchodního tajemství

Publication form

printed version "print"

References:

URL

RIV identification code

RIV/00216224:14740/12:00064867

Organization unit

Central European Institute of Technology

ISBN

978-3-659-18971-5

Keywords (in Czech)

mikroRNA; nekódující RNA; gastrointestinální nádory; prognóza; predikce; jednonukleotidové polymorfizmy; expresní profilování

Keywords in English

microRNAs; non-coding RNAs; gastrointestinal tumours; prognosis; prediction; single nucleotide polymorphisms; expression profiling

Abstract

V originále

Digestive tumours are the most frequent malignant tumours in the world and the leading cause of a cancer-related death. They are tough to treat once they have formed and many are not found until they have already spread to other parts of the body. Therefore, new biomarkers enabling early diagnosis of asymptomatic disease, accurate differentiation among particular clinical stages and individualization of therapy are sorely needed. With improved methods to explore the transcriptome, different types of non-coding RNAs have been identified. It was proved that these molecules are highly deregulated in cancer tissue and involved in important molecular and biological processes such as differentiation, proliferation, apoptosis, migration or cell cycle. Moreover, detailed analyses revealed that they could serve as new molecular markers useful for cancer classification, prognostic stratification, and drug response prediction. Non-coding RNAs in Gastrointestinal Cancer offers a comprehensive collection of current information about the role of non coding RNAs in gastrointestinal cancer pathogenesis and illustrates, how this knowledge may be useful in medical practice.

Links

NT13549, research and development project

Name: Vytvoření diagnostické sady cirkulujících mikroRNA pro neinvazivní časnou diagnostiku a sledování pacientů s kolorektálním karcinomem

Citovat

FALTEJSKOVÁ, Petra and Ondřej SLABÝ. Non-coding RNAs in Gastrointestinal Cancer: Novel Biomarkers and Therapeutic Targets. první. Germany: LAP LAMBERT Academic Publishing, 2012, 104 pp. ISBN 978-3-659-18971-5.

@book{987947,
   author = {Faltejsková, Petra and Slabý, Ondřej},
   address = {Germany},
   edition = {první},
   keywords = {microRNAs; non-coding RNAs; gastrointestinal tumours; prognosis; prediction; single nucleotide polymorphisms; expression profiling},
   howpublished = {tištěná verze "print"},
   language = {eng},
   location = {Germany},
   isbn = {978-3-659-18971-5},
   publisher = {LAP LAMBERT Academic Publishing},
   title = {Non-coding RNAs in Gastrointestinal Cancer: Novel Biomarkers and Therapeutic Targets},
   url = {http://www.amazon.com/Non-coding-RNAs-Gastrointestinal-Cancer-Therapeutic/dp/3659189715},
   year = {2012}
}

TY  - BOOK
ID  - 987947
AU  - Faltejsková, Petra - Slabý, Ondřej
PY  - 2012
TI  - Non-coding RNAs in Gastrointestinal Cancer: Novel Biomarkers and Therapeutic Targets
VL  - Neuveden
PB  - LAP LAMBERT Academic Publishing
CY  - Germany
SN  - 9783659189715
KW  - microRNAs
KW  - non-coding RNAs
KW  - gastrointestinal tumours
KW  - prognosis
KW  - prediction
KW  - single nucleotide polymorphisms
KW  - expression profiling
UR  - http://www.amazon.com/Non-coding-RNAs-Gastrointestinal-Cancer-Therapeutic/dp/3659189715
L2  - http://www.amazon.com/Non-coding-RNAs-Gastrointestinal-Cancer-Therapeutic/dp/3659189715
N2  - Digestive tumours are the most frequent malignant tumours in the world and the leading cause of a cancer-related death. They are tough to treat once they have formed and many are not found until they have already spread to other parts of the body. Therefore, new biomarkers enabling early diagnosis of asymptomatic disease, accurate differentiation among particular clinical stages and individualization of therapy are sorely needed. With improved methods to explore the transcriptome, different types of non-coding RNAs have been identified. It was proved that these molecules are highly deregulated in cancer tissue and involved in important molecular and biological processes such as differentiation, proliferation, apoptosis, migration or cell cycle. Moreover, detailed analyses revealed that they could serve as new molecular markers useful for cancer classification, prognostic stratification, and drug response prediction. Non-coding RNAs in Gastrointestinal Cancer offers a comprehensive collection of current information about the role of non coding RNAs in gastrointestinal cancer pathogenesis and illustrates, how this knowledge may be useful in medical practice.
ER  -

FALTEJSKOVÁ, Petra and Ondřej SLABÝ. \textit{Non-coding RNAs in Gastrointestinal Cancer: Novel Biomarkers and Therapeutic Targets}. první. Germany: LAP LAMBERT Academic Publishing, 2012, 104 pp. ISBN~978-3-659-18971-5.

Detailed Information on Publication Record