FALTEJSKOVÁ, Petra and Ondřej SLABÝ. Non-coding RNAs in Gastrointestinal Cancer: Novel Biomarkers and Therapeutic Targets. první. Germany: LAP LAMBERT Academic Publishing, 2012, 104 pp. ISBN 978-3-659-18971-5.
Other formats:   BibTeX LaTeX RIS
Basic information
Original name Non-coding RNAs in Gastrointestinal Cancer: Novel Biomarkers and Therapeutic Targets
Name in Czech Nekódující RNA u nádorů gastrointestinálního traktu
Authors FALTEJSKOVÁ, Petra (203 Czech Republic, belonging to the institution) and Ondřej SLABÝ (203 Czech Republic, guarantor, belonging to the institution).
Edition první. Germany, 104 pp. 2012.
Publisher LAP LAMBERT Academic Publishing
Other information
Original language English
Type of outcome Book on a specialized topic
Field of Study 30200 3.2 Clinical medicine
Country of publisher Germany
Confidentiality degree is not subject to a state or trade secret
Publication form printed version "print"
WWW URL
RIV identification code RIV/00216224:14740/12:00064867
Organization unit Central European Institute of Technology
ISBN 978-3-659-18971-5
Keywords (in Czech) mikroRNA; nekódující RNA; gastrointestinální nádory; prognóza; predikce; jednonukleotidové polymorfizmy; expresní profilování
Keywords in English microRNAs; non-coding RNAs; gastrointestinal tumours; prognosis; prediction; single nucleotide polymorphisms; expression profiling
Tags ok, rivok
Tags International impact, Reviewed
Changed by Changed by: Olga Křížová, učo 56639. Changed: 10/4/2013 00:52.
Abstract
Digestive tumours are the most frequent malignant tumours in the world and the leading cause of a cancer-related death. They are tough to treat once they have formed and many are not found until they have already spread to other parts of the body. Therefore, new biomarkers enabling early diagnosis of asymptomatic disease, accurate differentiation among particular clinical stages and individualization of therapy are sorely needed. With improved methods to explore the transcriptome, different types of non-coding RNAs have been identified. It was proved that these molecules are highly deregulated in cancer tissue and involved in important molecular and biological processes such as differentiation, proliferation, apoptosis, migration or cell cycle. Moreover, detailed analyses revealed that they could serve as new molecular markers useful for cancer classification, prognostic stratification, and drug response prediction. Non-coding RNAs in Gastrointestinal Cancer offers a comprehensive collection of current information about the role of non coding RNAs in gastrointestinal cancer pathogenesis and illustrates, how this knowledge may be useful in medical practice.
Links
NT13549, research and development projectName: Vytvoření diagnostické sady cirkulujících mikroRNA pro neinvazivní časnou diagnostiku a sledování pacientů s kolorektálním karcinomem
PrintDisplayed: 26/4/2024 08:10