BIENERTOVÁ VAŠKŮ, Julie, Petr BIENERT, Filip ZLÁMAL, Josef TOMANDL, Martin FOREJT, Marie TOMANDLOVÁ, Martin VAVŘINA, Jana KUDĚLKOVÁ, Zbyněk ŠPLÍCHAL and Anna VAŠKŮ. B-cell activating factor (BAFF) – a new factor linking immunity to diet? Central European Journal of Medicine. 2012, vol. 7, No 3, p. 275-283. ISSN 1895-1058. doi:10.2478/s11536-011-0153-7.
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Basic information
Original name B-cell activating factor (BAFF) – a new factor linking immunity to diet?
Authors BIENERTOVÁ VAŠKŮ, Julie (203 Czech Republic, guarantor, belonging to the institution), Petr BIENERT (203 Czech Republic, belonging to the institution), Filip ZLÁMAL (203 Czech Republic, belonging to the institution), Josef TOMANDL (203 Czech Republic, belonging to the institution), Martin FOREJT (203 Czech Republic, belonging to the institution), Marie TOMANDLOVÁ (203 Czech Republic, belonging to the institution), Martin VAVŘINA (203 Czech Republic, belonging to the institution), Jana KUDĚLKOVÁ (203 Czech Republic, belonging to the institution), Zbyněk ŠPLÍCHAL (203 Czech Republic, belonging to the institution) and Anna VAŠKŮ (203 Czech Republic, belonging to the institution).
Edition Central European Journal of Medicine, 2012, 1895-1058.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30000 3. Medical and Health Sciences
Country of publisher Poland
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 0.262
RIV identification code RIV/00216224:14110/12:00060623
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.2478/s11536-011-0153-7
UT WoS 000304396200001
Keywords in English BAFF; Obesity; Dietary composition; Diet; Anthropometry
Tags International impact
Changed by Changed by: Mgr. Michal Petr, učo 65024. Changed: 20. 8. 2012 11:26.
Abstract
B cell activation factor (BAFF) is a recently discovered member of the TNF ligand superfamily secreted by adipocytes, previously linked to autoimmune and lymphoproliferative disease. The aim of this study was to investigate the relationship between BAFF plasma levels and the non-modified, usual dietary composition as well as obesity-related anthropometric parameters in a cohort of 58 obese and non-obese Central-European Caucasian individuals. We found that BAFF had an independent predictive role for percentage of body fat; moreover, BAFF levels were correlated with waist and hip circumference. BAFF plasma levels were also significantly correlated with investigated dietary composition based on the 7-day food records, as the BAFF levels correlated with the percentage of energy derived from the carbohydrates and with energy derived from the dietary fat. Our results suggest that BAFF may play a role in linking the immune status and metabolic response to diet.
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CEJMED_BAFF.pdf   File version Petr, M. 20. 8. 2012

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  • a concrete person prof. MUDr. Anna Vašků, CSc., učo 122
  • a concrete person Mgr. Zbyněk Šplíchal, Ph.D., učo 151051
  • a concrete person Mgr. Martin Forejt, Ph.D., učo 16739
  • a concrete person Mgr. Marie Tomandlová, Ph.D., učo 1693
  • a concrete person doc. RNDr. Josef Tomandl, Ph.D., učo 47
  • a concrete person prof. MUDr. Julie Dobrovolná, Ph.D., učo 4805
  • a concrete person Bc. Petr Bienert, učo 50773
  • a concrete person MUDr. Jana Kudělková, učo 51995
  • a concrete person Mgr. Michal Petr, učo 65024
  • a concrete person MUDr. Martin Vavřina, učo 73806
  • a concrete person Mgr. et Mgr. Filip Zlámal, Ph.D., učo 78448
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