PĚNČÍKOVÁ, Kristýna, Jana URBANOVÁ and Eva TÁBORSKÁ. Occurrence of quaternary benzo[c]phenanthridine alkaloids in Stylophorum lasiocarpum (Oliv.) fedde. In International Congress Natural Anticancer Drugs. 2012. ISSN 1213-8118.
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Original name Occurrence of quaternary benzo[c]phenanthridine alkaloids in Stylophorum lasiocarpum (Oliv.) fedde
Authors PĚNČÍKOVÁ, Kristýna (203 Czech Republic, belonging to the institution), Jana URBANOVÁ (203 Czech Republic, belonging to the institution) and Eva TÁBORSKÁ (203 Czech Republic, guarantor, belonging to the institution).
Edition International Congress Natural Anticancer Drugs, 2012.
Other information
Original language English
Type of outcome Conference abstract
Field of Study 10600 1.6 Biological sciences
Country of publisher Czech Republic
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 0.990
RIV identification code RIV/00216224:14110/12:00060640
Organization unit Faculty of Medicine
ISSN 1213-8118
Keywords in English Stylophorum lasiocarpum; QBA; sanguinarine; chelerythrine
Tags International impact
Changed by Changed by: Mgr. Michal Petr, učo 65024. Changed: 23. 8. 2012 10:02.
Abstract
For a long time, quaternary benzo[c]phenanthridine alkaloids (QBAs) are known to exhibit diverse biological effects. A great deal of attention is devoted to the main alkaloids sanguinarine (SA ) and chelerythrine (CHE) and their cytotoxicity and induction of apoptosis. These alkaloids also display important anti-proliferative activities against cancer cell lines and have been discussed as potential cytostatic drugs for cancer treatment. In the last years also the other QBAs have received increased attention and new information regarding their biological activities has been published.
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LH12176, research and development projectName: Benzofenanthridinové alkaloidy - studium účinků na celulární a molekulární úrovni (Acronym: KBF)
Investor: Ministry of Education, Youth and Sports of the CR, KONTAKT II
MUNI/A/0831/2011, internal MU codeName: Příspěvek chemických a biochemických metodik ke studiu molekulární podstaty vybraných patologických stavů a onemocnění
Investor: Masaryk University, Grant Agency of Masaryk University, Category A
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konferencni_prispevky_Olomouc.pdf   File version Petr, M. 22. 8. 2012

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  • a concrete person prof. RNDr. Eva Táborská, CSc., učo 1068
  • a concrete person PharmDr. Kristýna Šebrlová, Ph.D., učo 107479
  • a concrete person Mgr. Jana Kantorová, učo 151188
  • a concrete person Mgr. Michal Petr, učo 65024
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