POLANSKÁ, Eva, Zuzana DOBŠÁKOVÁ, Martina DVOŘÁČKOVÁ, Jiří FAJKUS and Michal ŠTROS. HMGB1 gene knockout in mouse embryonic fibroblasts results in reduced telomerase activity and telomere dysfunction. Chromosoma. New York: Springer, 2012, vol. 121, No 4, p. 419-431. ISSN 0009-5915. Available from: https://dx.doi.org/10.1007/s00412-012-0373-x. |
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@article{990390, author = {Polanská, Eva and Dobšáková, Zuzana and Dvořáčková, Martina and Fajkus, Jiří and Štros, Michal}, article_location = {New York}, article_number = {4}, doi = {http://dx.doi.org/10.1007/s00412-012-0373-x}, keywords = {REPEAT AMPLIFICATION PROTOCOL; CHROMOSOMAL-PROTEIN HMG1; DNA-DAMAGE; CHROMATIN; MAINTENANCE; BINDING; EXPRESSION; COMPLEXES; GENOME; GROWTH}, language = {eng}, issn = {0009-5915}, journal = {Chromosoma}, title = {HMGB1 gene knockout in mouse embryonic fibroblasts results in reduced telomerase activity and telomere dysfunction}, url = {http://link.springer.com/article/10.1007%2Fs00412-012-0373-x}, volume = {121}, year = {2012} }
TY - JOUR ID - 990390 AU - Polanská, Eva - Dobšáková, Zuzana - Dvořáčková, Martina - Fajkus, Jiří - Štros, Michal PY - 2012 TI - HMGB1 gene knockout in mouse embryonic fibroblasts results in reduced telomerase activity and telomere dysfunction JF - Chromosoma VL - 121 IS - 4 SP - 419-431 EP - 419-431 PB - Springer SN - 00095915 KW - REPEAT AMPLIFICATION PROTOCOL KW - CHROMOSOMAL-PROTEIN HMG1 KW - DNA-DAMAGE KW - CHROMATIN KW - MAINTENANCE KW - BINDING KW - EXPRESSION KW - COMPLEXES KW - GENOME KW - GROWTH UR - http://link.springer.com/article/10.1007%2Fs00412-012-0373-x L2 - http://link.springer.com/article/10.1007%2Fs00412-012-0373-x N2 - Telomere repeats are added onto chromosome ends by telomerase, consisting of two main core components: a catalytic protein subunit (telomerase reverse trancriptase, TERT), and an RNA subunit (telomerase RNA, TR). The ability of HMGB1 to modulate cellular activity of telomerase and to maintain telomere integrity can help to understand some aspects of the protein involvement in chromosome stability and cancer. ER -
POLANSKÁ, Eva, Zuzana DOBŠÁKOVÁ, Martina DVOŘÁČKOVÁ, Jiří FAJKUS and Michal ŠTROS. HMGB1 gene knockout in mouse embryonic fibroblasts results in reduced telomerase activity and telomere dysfunction. \textit{Chromosoma}. New York: Springer, 2012, vol.~121, No~4, p.~419-431. ISSN~0009-5915. Available from: https://dx.doi.org/10.1007/s00412-012-0373-x.
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