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@article{991721, author = {Přikryl, Radovan}, article_location = {Praha}, article_number = {1}, keywords = {case report; clinical experience; extrapyr amidal side effects; paliperidone; treatment}, language = {eng}, issn = {1337-933X}, journal = {Activitas Nervosa Superior Rediviva}, title = {Alleviation of extrapyramidal side effects upon switching from risperidone to paliperidone}, url = {http://www.rediviva.sav.sk/53i1/14.pdf}, volume = {53}, year = {2011} }
TY - JOUR ID - 991721 AU - Přikryl, Radovan PY - 2011 TI - Alleviation of extrapyramidal side effects upon switching from risperidone to paliperidone JF - Activitas Nervosa Superior Rediviva VL - 53 IS - 1 SP - 14-16 EP - 14-16 PB - Collegium Internationale Activitatis N.S SN - 1337933X KW - case report KW - clinical experience KW - extrapyr amidal side effects KW - paliperidone KW - treatment UR - http://www.rediviva.sav.sk/53i1/14.pdf L2 - http://www.rediviva.sav.sk/53i1/14.pdf N2 - Paliperidone is a new second generation antipsychotic; in terms of pharmacology, it is an active metabolite of risperidone. Compared to risperidone, paliperidone should thus show more stable occupation of dopamine receptors in the brain, which on one the hand may lead to increased antipsychotic efficacy, and on the other hand to reduced incidence of adverse extrapyramidal effects. The case report describes alleviation of Parkinson’s syndrome induced by risperidone by switching to paliperidone in a young man with a new occurrence of a paranoid schizophrenia episode. Thanks to its clinical efficacy, paliperi- done is ranked among the most successful second generation antipsychotics with reduced extrapyramidal symptomatology ER -
PŘIKRYL, Radovan. Alleviation of extrapyramidal side effects upon switching from risperidone to paliperidone. \textit{Activitas Nervosa Superior Rediviva}. Praha: Collegium Internationale Activitatis N.S, 2011, vol.~53, No~1, p.~14-16. ISSN~1337-933X.
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