Operace mízních uzlin u karcinomů prsu - současný pohled.

COUFAL, Oldřich, Pavlína VRTĚLOVÁ and Petr KRSIČKA. Operace mízních uzlin u karcinomů prsu - současný pohled. (Lymphatic node surgery in breast carcinoma therapy, Current view.). Postgraduální medicína. Praha: Mladá fronta, 2012, vol. 14, No 4, p. 376-383. ISSN 1212-4184.

Basic information

• Original name: Operace mízních uzlin u karcinomů prsu - současný pohled.
• Name (in English): Lymphatic node surgery in breast carcinoma therapy, Current view.
• Authors: COUFAL, Oldřich (203 Czech Republic, guarantor, belonging to the institution), Pavlína VRTĚLOVÁ (203 Czech Republic) and Petr KRSIČKA (203 Czech Republic).
• Edition: Postgraduální medicína, Praha, Mladá fronta, 2012, 1212-4184.

Other information

• Original language: Czech
• Type of outcome: Article in a journal
• Field of Study: 30200 3.2 Clinical medicine
• Country of publisher: Czech Republic
• Confidentiality degree: is not subject to a state or trade secret
• RIV identification code: RIV/00216224:14110/12:00060860
• Organization unit: Faculty of Medicine
• Keywords (in Czech): karcinom prsu; biopsie sentinelové uzliny; disekce axily
• Keywords in English: breast carcinoma; sentinel node biopsy; axillar dissection

Abstract

Nedílnou součástí chirurgické léčby karcinomů prsu je operace spádových mízních uzlin. Jejich odstranění lze považovat za kurativní, pokud jsou výrazně metastaticky postiženy. V ostatních případech má zákrok smysl především pro posouzení rozsahu onemocnění a volbu adjuvantní terapie.

Abstract (in English)

Surgery of associated lymphatic nodes is an inseparable part of breast carcinoma therapy. Their removal can be considered curative if they are significantly affected by metastases. In other cases, the surgery is meaningful mostly in terms of determining the disease's extent and choosing an adjuvant therapy. Non-selective dissection of the axilla performed in all patients without any distinction can no longer be accepted, because this procedure carries a high risk of both short-term and long-term complications. Biopsy of the sentinel node has become a clear first choice among this type of procedures. Possible contraindifocuscourses of action in cases of unsuccessful identification and the importance of extra-axillar locations are however also being discussed. New data shows that not even in the case of the sentinel node being affected by a tumour, axillar dissection is necessarily desirable in all patients. A gradual decrease in how radical the surgical solutions are can be observed, it does not seem however that the local surgical intervention would be poised to lose its important place in breast carcinoma therapy. The role of surgical procedures to the lymphatic nodes remains crucial and their correct indication requires increasing amounts of experience and theoretical knowledge.