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    2024

    1. FoxO1/Rictor axis induces a non-genetic adaptation to Ibrutinib via Akt activation in chronic lymphocytic leukemia
      ONDRIŠOVÁ, Laura, Václav ŠEDA, Kryštof HLAVÁČ, Petra PAVELKOVÁ, Eva HOFERKOVÁ, Giorgia CHIODIN, Lenka KOŠŤÁLOVÁ, Gabriela MLADONICKÁ PAVLASOVÁ, Daniel FILIP, Josef VEČEŘA, Pedro FARIA ZENI, Jan OPPELT, Zuzana KAHOUNOVÁ, Rachel VICHOVA, Karel SOUČEK, Anna PANOVSKÁ, Karla PLEVOVÁ, Šárka POSPÍŠILOVÁ, Martin ŠIMKOVIČ, Filip VRBACKÝ, Daniel LYSÁK, Stacey M. FERNANDES, M.S. DAVIDS, Alba MAIQUES-DIAZ, Stella CHARALAMPOPOULOU, Jose I. MARTIN-SUBERO, Jenifer R. BROWN, Michael DOUBEK, Jiří MAYER and Marek MRÁZ. FoxO1/Rictor axis induces a non-genetic adaptation to Ibrutinib via Akt activation in chronic lymphocytic leukemia. The Journal of Clinical Investigation. 2024. Available from: https://dx.doi.org/10.1172/JCI173770.
      More: https://is.muni.cz/publication/2446258/en
    2. Integrative NGS testing reveals clonal dynamics of adverse genomic defects contributing to a natural progression in treatment-naïve CLL patients
      NAVRKALOVÁ, Veronika, Karla PLEVOVÁ, Lenka RADOVÁ, Jakub Paweł PORC, Karol PÁL, Jitka MALČÍKOVÁ, Šárka PAVLOVÁ, Michael DOUBEK, Anna PANOVSKÁ, Jana KOTAŠKOVÁ and Šárka POSPÍŠILOVÁ. Integrative NGS testing reveals clonal dynamics of adverse genomic defects contributing to a natural progression in treatment-naïve CLL patients. British journal of haematology. Hoboken: Wiley-Blackwell, 2024, vol. 204, No 1, p. 240-249. ISSN 0007-1048. Available from: https://dx.doi.org/10.1111/bjh.19191.
      More: https://is.muni.cz/publication/2372237/en
    3. The Genomic Landscape of Lymphomas Invading the Central Nervous System Inferred from Cell-Free DNA by Integrative NGS Analysis and the Diagnostic Benefit Compared to Flow Cytometry
      NAVRKALOVÁ, Veronika, Andrea MARECKOVA, Viera HRABCAKOVA, Samuel HRICKO, Jakub Paweł PORC, Martina FILIPOVÁ, Andrea JANÍKOVÁ and Jana KOTAŠKOVÁ. The Genomic Landscape of Lymphomas Invading the Central Nervous System Inferred from Cell-Free DNA by Integrative NGS Analysis and the Diagnostic Benefit Compared to Flow Cytometry. In Annual Meeting of the Association-for-Molecular-Pathology (AMP). 2024. ISSN 1525-1578.
      More: https://is.muni.cz/publication/2431608/en
    4. The non-canonical BAF chromatin remodeling complex is a novel target of spliceosome dysregulation in SF3B1-mutated chronic lymphocytic leukemia
      HAGERSTRAND, Daniel, Blaz ODER, Diego CORTESE, Ying QU, Amrei BINZER-PANCHAL, Cecilia OSTERHOLM, Teresa Del Peso SANTOS, Leily RABBANI, Hassan Foroughi ASL, Aron SKAFTASON, Viktor LJUNGSTROM, August LUNDHOLM, Maria KOUTROUMANI, Zahra HAIDER, Cecilia JYLHA, John MOLLSTEDT, Larry MANSOURI, Karla PLEVOVÁ, Andreas AGATHANGELIDIS, Lydia SCARFO, Marine ARMAND, Alice F MUGGEN, Neil E KAY, Tait SHANAFELT, Davide ROSSI, Lukas M ORRE, Šárka POSPÍŠILOVÁ, Konstantin BARYLYUK, Frederic DAVI, Mattias VESTERLUND, Anton W LANGERAK, Janne LEHTIO, Paolo GHIA, Kostas STAMATOPOULOS, Lesley-Ann SUTTON and Richard ROSENQUIST. The non-canonical BAF chromatin remodeling complex is a novel target of spliceosome dysregulation in SF3B1-mutated chronic lymphocytic leukemia. Leukemia. LONDON: SPRINGERNATUR, 2024, 14 pp. ISSN 0887-6924. Available from: https://dx.doi.org/10.1038/s41375-024-02379-4.
      More: https://is.muni.cz/publication/2447550/en
    5. The 1+Million Genomes Minimal Dataset for Cancer
      RIBA, Michela, Cinzia SALA, Aedin C CULHANE, Asmund FLOBAK, Attila PATOCS, Kjetil BOYE, Karla PLEVOVÁ, Šárka POSPÍŠILOVÁ, Giorgia GANDOLFI, Marco J MORELLI, Gabriele BUCCI, Anders EDSJO, Ulrik LASSEN, Fatima AL-SHAHROUR, Nuria LOPEZ-BIGAS, Randi HOVLAND, Edwin CUPPEN, Alfonso VALENCIA, Helene A POIREL, Richard ROSENQUIST, Serena SCOLLEN, Juan Arenas MARQUEZ, Jeroen BELIEN, De Nicolo ARCANGELA, De Maria RUGGERO, David TORRENTS and Giovanni TONON. The 1+Million Genomes Minimal Dataset for Cancer. Nature genetics. Berlin: Nature Publishing Group, 2024, vol. 56, No 5, p. 733-736. ISSN 1061-4036. Available from: https://dx.doi.org/10.1038/s41588-024-01721-x.
      More: https://is.muni.cz/publication/2407780/en
    6. Unveiling the dynamics and molecular landscape of a rare chronic lymphocytic leukemia subpopulation driving refractoriness: insights from single-cell RNA sequencing
      KURUCOVÁ, Terézia, Kamila RÉBLOVÁ, Pavlína JANOVSKÁ, Jakub Paweł PORC, Veronika NAVRKALOVÁ, Šárka PAVLOVÁ, Jitka MALČÍKOVÁ, Karla PLEVOVÁ, Boris TICHÝ, Michael DOUBEK, Vítězslav BRYJA, Jana KOTAŠKOVÁ and Šárka POSPÍŠILOVÁ. Unveiling the dynamics and molecular landscape of a rare chronic lymphocytic leukemia subpopulation driving refractoriness: insights from single-cell RNA sequencing. Molecular oncology. Hoboken: Wiley, 2024, 13 pp. ISSN 1574-7891. Available from: https://dx.doi.org/10.1002/1878-0261.13663.
      More: https://is.muni.cz/publication/2407762/en
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