Publication Records

FISCHMANN, Thierry, Alan HRUZA, Jose DUCA, Lata RAMANATHAN, Todd MAYHOOD, William WINDSOR, Hung LE, Timothy GUZI, Michael DWYER, Kamil PARUCH, Ronald DOLL, Emma LEES, David PARRY, Wolfgang SEGHEZZI and Vincent MADISON. Structure-guided discovery of cyclin-dependent kinase inhibitors. Biopolymers. 2008, vol. 2008, No 89, p. 372-379. ISSN 0006-3525.

VAŇHARA, Petr, Vítězslav BRYJA, Viktor HORVÁTH, Alois KOZUBÍK, Aleš HAMPL and Jan ŠMARDA. c-Jun induces apoptosis of serum-deprived BM2 monoblasts by activating cyclin A-associated CDK2 kinase. In Analytical Cytometry IV. Brno: Czech Society for Analytical Cytology, 2007, p. 138-139. ISBN 978-80-239-9591-6.

VAŇHARA, Petr, Vítězslav BRYJA, Viktor HORVÁTH, Alois KOZUBÍK, Aleš HAMPL and Jan ŠMARDA. c-Jun induces apoptosis of starved BM2 monoblasts by activating cyclin A-CDK2. Biochemical and Biophysical Research Communications. San Diego (USA): Academic Press, 2007, vol. 353, No 1, p. 92-97. ISSN 0006-291X.

DWYER, Michael, Kamil PARUCH, Carmen ALVAREZ, Ronald DOLL, Kerry KEERTIKAR, Jose DUCA, Thierry FISCHMANN, Alan HRUZA, Vincent MADISON, Emma LEES, David PARRY, Wolfgang SEGHEZZI, Nicole SGAMBELLONE, Frances SHANAHAN, Derek WISWELL and Timothy GUZI. Versatile templates for the development of novel kinase inhibitors: Discovery of novel CDK inhibitors. Bioorganic & Medicinal Chemistry Letters. 2007, vol. 2007, No 17, p. 6216-6219. ISSN 0960-894X.

PARUCH, Kamil, Timothy GUZI, Michael DWYER and Gerald SHIPPS. Pyrazolopyrimidines as Protein Kinase Inhibitors. 2006.

OTYEPKA, Michal, Iveta BÁRTOVÁ, Zdeněk KŘÍŽ and Jaroslav KOČA. Dynamics of human CDK2 and CDK5 studied by computer simulations. In Cellular and Molecular Biology Letters. Wroclaw: Department of Genetic Biochemistry, Institute of Biochemistry, University of Wroclaw, 2005, p. 116-117. ISBN 1425-8153.

OTYEPKA, Michal, Iveta BÁRTOVÁ, Zdeněk KŘÍŽ and Jaroslav KOČA. Dynamika regulačních enzymů buněčných procesů CDK2 a CDK5 studovaná molekulovou dynamikou (Dynamics of human CDK2 and CDK5 studied by computer simulations). In ChemZi. Bratislava: Slovenská chemická spoločnosť, 2005, p. 277-277. ISBN 1336 - 7242.

BÁRTOVÁ, Iveta, Michal OTYEPKA, Zdeněk KŘÍŽ and Jaroslav KOČA. Molecular Dynamics Simulations on Cyclin Dependent Kinase 2. Solvent Behavior Analysis and Activation and Inhibition by Phosphorylation -Tools to Design New Inhibitors and Contribute to Understanding Mechanism. In WATOC 2005. Modeling Structure and Reactivity. Cape Town: WATOC 2005., 2005, p. 83-83.

KŘÍŽ, Zdeněk, Michal OTYEPKA and Jaroslav KOČA. Hydratace aktivniho mista enzymu CDK2. Studium pomoci molekulove dynamiky. (Hydration of the CDK2 active site. Molecular dynamics study.). In Chemicke listy 6. Praha: 54. Sjezd chemickych spolecnosti, 2002, p. 424.