Cardio-Ankle Vascular Index in Heterozygous Familial Hypercholesterolemia

@article{987425,
   author = {Soška, Vladimír and Dobšák, Petr and Dušek, Ladislav and Shirai, Kohji and Jarkovský, Jiří and Nováková, Marie and Brhel, Petr and Šťastná, Jana and Fajkusová, Lenka and Freiberger, Tomáš and Yambe, Tomoyuki},
   article_location = {TOKYO},
   article_number = {5},
   keywords = {Atherosclerosis; Cardio-ankle vascular index; Familial hypercholesterolemia; Statins; Ezetimibe},
   language = {eng},
   issn = {1340-3478},
   journal = {JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS},
   title = {Cardio-Ankle Vascular Index in Heterozygous Familial Hypercholesterolemia},
   volume = {19},
   year = {2012}
}

TY  - JOUR
ID  - 987425
AU  - Soška, Vladimír - Dobšák, Petr - Dušek, Ladislav - Shirai, Kohji - Jarkovský, Jiří - Nováková, Marie - Brhel, Petr - Šťastná, Jana - Fajkusová, Lenka - Freiberger, Tomáš - Yambe, Tomoyuki
PY  - 2012
TI  - Cardio-Ankle Vascular Index in Heterozygous Familial Hypercholesterolemia
JF  - JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS
VL  - 19
IS  - 5
SP  - 453-461
EP  - 453-461
PB  - JAPAN ATHEROSCLEROSIS SOC
SN  - 13403478
KW  - Atherosclerosis
KW  - Cardio-ankle vascular index
KW  - Familial hypercholesterolemia
KW  - Statins
KW  - Ezetimibe
N2  - Aim: The cardio-ankle vascular index (CAVI) is a new non-invasive marker of arterial stiffness and atherosclerosis. The purpose of this study was to compare CAVI in patients with heterozygous familial hypercholesterolemia (FH) and in healthy controls. Methods: 82 FH subjects (27 males, 65 females), aged 53.7 +/- 13.6 years without clinical symptoms of cardiovascular diseases and 359 healthy controls (121 males, 238 females), aged 43.9 +/- 14.9 years, were examined. CAVI was measured using the system VaSera (R) 1500. Results: CAVI in FH patients was significantly higher (8.0 +/- 1.4) than in healthy subjects (7.5 +/- 1.3) p=0.002; however, age, sex and BMI adjusted CAVI did not differ significantly (p=0.061) between the FH group (7.5, CI: 7.3; 7.7) and control group (7.7, CI: 7.6; 7.7). Conclusion: The study showed no significant difference in CAVI between heterozygous FH and healthy controls.
ER  - 

SOŠKA, Vladimír, Petr DOBŠÁK, Ladislav DUŠEK, Kohji SHIRAI, Jiří JARKOVSKÝ, Marie NOVÁKOVÁ, Petr BRHEL, Jana ŠŤASTNÁ, Lenka FAJKUSOVÁ, Tomáš FREIBERGER and Tomoyuki YAMBE. Cardio-Ankle Vascular Index in Heterozygous Familial Hypercholesterolemia. \textit{JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS}. TOKYO: JAPAN ATHEROSCLEROSIS SOC, 2012, vol.~19, No~5, p.~453-461. ISSN~1340-3478.