Diploma Thesis deals first of all with spectrophotometric and
mass-spectrometric study of the reaction of thymin containing
oligonucleotides (AAAAT, AATAA, AAAATT, AATTAA, ATATAA, ATAATA)
with OsO4-bipyridin (OsBipy) complex. It was confirmed via
spectrophotometry that more products are formed. MALDI TOF MS
study shows that OsBipy is reacting  first of all with thymin
which is oxidized to di-hydroxy product. But beside expected
products, e.g.	 AAAATT.OsBiPy, also other Os-containing
compounds are formed. Probable structures of some of the
products are proposed. MALDI TOF MS study is highly complicated
by formation of adducts with sodium and the matrices used.
In the second part, the preliminary results dealing with MS
detection of compounds eluted from walls of commerical PET
bottles are given and author’s extensive results concerning the
use of MALDI TOF MS for inorganic nano-materials(AgSbS2,
Ge2Sb2Te5, nanodiamonds) analysis are briefly commented.