Thesis/Dissertation: Bc. Zuzana Klímová: Effects of endocrine disrupting compounds on in vitro biomarkers of epigenetic toxicity
Master's thesis
Effects of endocrine disrupting compounds on in vitro biomarkers of epigenetic toxicity
Účinky endokrinních disruptorů na in vitro biomarkery epigenetické toxicity
Abstract
Endokrinní disruptory jsou různorodou skupinou látek, které mají schopnost narušovat hormonální systém. Mezi nejvíce studované mechanismy endokrinní disrupce patří interakce kontaminantů s hormonálními receptory a následné ovlivnění genové exprese (genomický mechanismus účinku). Endokrinní disruptory jsou schopny indukovat také rychlé změny v buněčném signálování. Tyto procesy mohou významným způsobem …more
Abstract
Endocrine disruptors are a diverse group of substances which have the ability to interfere with the hormonal system. Among the most studied mechanisms of endocrine disruption contaminants include interaction with hormone receptors and subsequent effect on gene expression (genomic mechanism of action). Endocrine disruptors are also able to induce rapid changes in cellular signaling. These processes …more
21/5/2015 10:12, doc. RNDr. Pavel Babica, Ph.D., UČO 12437
Consultant
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