Životopis

Curriculum Vitae

Personal Information

• Mgr. Pavel Dobeš, Ph.D.
  
  
• Date of Birth: November 11, 1984
• Place of Birth: Valasske Mezirici, Czech Republic

Contact Information

• E-mail: pavel.dobes.sci@gmail.com
• Section of Animal Physiology and Immunology, Department of Experimental Biology, Faculty of Science, Masaryk University, Brno, Czech Republic

Current position

• Assistant professor

Education and Academic Qualifications

• From 2015
  Faculty of Science, Masaryk University, Brno
  Assistant professor
  
• 2012 – 2015
  Faculty of Science, Masaryk University, Brno
  Postdoc
  Molecular mechanism of insects' immune and neurophysiological response to biotic and abiotic factors
  
• 2009 – 2012
  Faculty of Science, Masaryk University, Brno
  Doctoral degree programme
  Programme: Biology; Study field: Physiology of Animals
  Thesis: The nematobacterial complex Heterorhabditis – Photorhabdus and its influence on G. mellonella and D. melanogaster immunity
  
• 2007 – 2009
  Faculty of Science, Masaryk University, Brno
  Master's degree programme
  Programme: Biology; Study field: General Biology
  Thesis: Phenoloxidase system in insects
  
• 2004 – 2007
  Faculty of Science, Masaryk University, Brno
  Bachelor's degree programme
  Programme: Biology; Study field: General Biology
  Thesis: Humoral immunity of invertebrates
  
• 2000 – 2004
  Gymnazium Frantiska Palackeho in Valasske Mezirici
  Four-year study programme
  

Employment

• From 2018 assistant professor
  National Centre for Biomolecular Research, Faculty of Science, Masaryk University, Brno
  
• From 2015 assistant professor
  Department of Experimental Biology, Faculty of Science, Masaryk University, Brno
  
• 2012 - 2015 postdoc
  Department of Experimental Biology, Faculty of Science, Masaryk University, Brno
  

Teaching Activities

• Animal Biology - practical course (Bi6790c)
• Animal Physiology - practical course (Bi3030c)
• Animal Physiology Demonstrations (Bi3031)
• Developmental and Comparative Immunology - practical course (Bi8250c)
• Immunology - practical course (Bi5220c)
• Journal club of animal physiology (Bi9904, Bi9905)
• Mechanisms of hormonal regulation (Bi1100)
• Information technology in biology (Bi5610)
• supervisor of bachelor and diploma theses

Professional Stays

• 1.9.2009 – 22.12.2009 Stockholm University, Sweden
• 9.5.2011 – 14.5.2011 Zonguldak Karaelmas University, Turkey
• 3.6.2011 – 5.9.2011 Stockholm University, Sweden
• 15.2.2012 – 19.2.2012 Stockholm University, Sweden
• 12.5.2012 – 17.5.2012 University of Bari, Italy
• 2.7.2012 – 5.8.2012 Stockholm University, Sweden
• 3.9.2012 – 7.9.2012 University of Turku, Finland
• 2.1.2013 – 14.2.2013 Stockholm University, Sweden
• 15.7.2013 – 31.8.2013 Stockholm University, Sweden
• 1.1.2015 – 25.1.2015 University of Azores, Portugal
• 29.1.2015 – 12.2.2015 Mississippi State University, USA
• 7.6.2016 – 12.6.2016 Stockholm University, Sweden
• 26.4.2017 – 29.4.2017 Maynooth University, Ireland
• 17.2.2018 – 26.2.2018 University of Azores, Portugal
• 5.8.2018 – 10.8.2018 Stockholm University, Sweden

Awards and Certificates Related to Science and Research

• 2019 Accredited Qualification Course: Professional medical laboratory methods (AKK Odborné zdravotnické laboratorní metody
• 2013 Dean's Award for outstanding dissertation work

Selected Publications

• KUNC, Martin, Pavel DOBEŠ, Rachel WARD, Saetbyeol LEE, Radim ČEGAN, Silvie DOSTÁLKOVÁ, Kateřina HOLUŠOVÁ, Jana HURYCHOVÁ, Sara ELIÁŠ, Eliška PINĎÁKOVÁ, Eliška ČUKANOVÁ, Jana PRODĚLALOVÁ, Marek PETŘIVALSKÝ, Jiří DANIHLÍK, Jaroslav HAVLÍK, Roman HOBZA, Kevin KAVANAGH a Pavel HYRŠL. Omics-based analysis of honey bee (Apis mellifera) response to Varroa sp. parasitisation and associated factors reveals changes impairing winter bee generation. Insect Biochemistry and Molecular Biology. Elsevier, 2023, roč. 152, January, s. 1-19. ISSN 0965-1748. Dostupné z: https://dx.doi.org/10.1016/j.ibmb.2022.103877. URL info
• BEANI POIANI, Silvana, Pavel DOBEŠ, Martin KUNC, Mayara Cristina PEREIRA, Odair Correa BUENO a Pavel HYRŠL. The Influence of Selected Insecticides on the Oxidative Response of Atta sexdens (Myrmicinae, Attini) Workers. Neotropical Entomology. Springer, 2023, roč. 52, č. 6, s. 1088-1099. ISSN 1519-566X. Dostupné z: https://dx.doi.org/10.1007/s13744-023-01077-7. URL info
• LEE, Saetbyeol, Filip KALCIC, Iola F. DUARTE, Dalibor TITERA, Martin KAMLER, Pavel MRNA, Pavel HYRŠL, Jiri DANIHLIK, Pavel DOBEŠ, Martin KUNC, Anna PUDLO a Jaroslav HAVLIK. 1H NMR Profiling of Honey Bee Bodies Revealed Metabolic Differences between Summer and Winter Bees. Insects. MDPI, 2022, roč. 13, č. 2, s. 1-13. ISSN 2075-4450. Dostupné z: https://dx.doi.org/10.3390/insects13020193. URL info
• DOBEŠ, Pavel, Martin KUNC, Jana HURYCHOVÁ, Sara ELIÁŠ a Pavel HYRŠL. Omics-based approach to study honey bee (Apis mellifera) response to parasitic mite Varroa sp. and associated pathogens. In Frontiers in Physiology and Disease. 2022. info
• FUJDIAROVÁ, Eva, Josef HOUSER, Pavel DOBEŠ, Gita PAULÍKOVÁ, Nikolaj KONDAKOV, Leonid KONONOV, Pavel HYRŠL a Michaela WIMMEROVÁ. Heptabladed b-propeller lectins PLL2 and PHL from Photorhabdus spp. recognize O-methylated sugars and influence the host immune system. The FEBS Journal. Hoboken: Wiley, 2021, roč. 288, č. 4, s. 1343-1365. ISSN 1742-464X. Dostupné z: https://dx.doi.org/10.1111/febs.15457. URL info
• DOBEŠ, Pavel, Martin KUNC, Jana HURYCHOVÁ, Alena VOTAVOVÁ, Olga KOMZÁKOVÁ a Pavel HYRŠL. The Effect of Foraging on Bumble Bees, Bombus terrestris, Reared under Laboratory Conditions. Insects. Basel: MDPI, 2020, roč. 11, č. 5, s. 1-15. ISSN 2075-4450. Dostupné z: https://dx.doi.org/10.3390/insects11050321. URL info
• ELIÁŠ, Sara, Jana HURYCHOVÁ, Duarte Nuno TOUBARRO TIAGO, Jorge FRIAS, Martin KUNC, Pavel DOBEŠ, Nelson SIMÕES a Pavel HYRŠL. Bioactive Excreted/Secreted Products of Entomopathogenic Nematode Heterorhabditis bacteriophora Inhibit the Phenoloxidase Activity during the Infection. Insects. Basel: MDPI, 2020, roč. 11, č. 6, s. 1-19. ISSN 2075-4450. Dostupné z: https://dx.doi.org/10.3390/insects11060353. URL info
• DOBEŠ, Pavel, Eva FUJDIAROVÁ, Josef HOUSER, Gita JANČAŘÍKOVÁ, Pavel HYRŠL a Michaela WIMMEROVÁ. Photorhabdus lectins disrupt the activity of insect and human immune system. In International Congress on Invertebrate Pathology and Microbial Control & 52nd Annual Meeting of the Society for Invertebrate Pathology & 17th Meeting of the IOBC‐WPRS Working Group “Microbial and Nematode Control of Invertebrate Pests”. 2019. info
• ŘEŘICHA, Michal, Pavel DOBEŠ, Pavel HYRŠL a Michal KNAPP. Ontogeny of protein concentration, haemocyte concentration and antimicrobial activity against Escherichia coli in haemolymph of the invasive harlequin ladybird Harmonia axyridis (Coleoptera: Coccinellidae). Physiological Entomology. Wiley-Blackwell, The Royal Entomological Society, 2018, roč. 43, č. 2, s. 51-59. ISSN 0307-6962. Dostupné z: https://dx.doi.org/10.1111/phen.12224. URL info
• KNAPP, Michal, Pavel DOBEŠ, Michal ŘEŘICHA a Pavel HYRŠL. Puncture vs. reflex bleeding: Haemolymph composition reveals significant differences among ladybird species (Coleoptera: Coccinellidae), but not between sampling methods. European Journal of Entomology. AV ČR, Institute of Entomology of the Czech Academy of Sciences, 2018, roč. 115, č. 1, s. 1-6. ISSN 1802-8829. Dostupné z: https://dx.doi.org/10.14411/eje.2018.001. URL info
• IBRAHIM, Emad, Pavel DOBEŠ, Martin KUNC, Pavel HYRŠL a Dalibor KODRÍK. Adipokinetic hormone and adenosine interfere with nematobacterial infection and locomotion in Drosophila melanogaster. Journal of Insect Physiology. Kidlington, England: Elsevier, 2018, roč. 107, č. 4, s. 167-174. ISSN 0022-1910. Dostupné z: https://dx.doi.org/10.1016/j.jinsphys.2018.04.002. URL info
• DOBEŠ, Pavel, Gita JANČAŘÍKOVÁ, Atul KUMAR, Eva FUJDIAROVÁ, Josef HOUSER, Pavel HYRŠL a Michaela WIMMEROVÁ. Biological role of PLL and PHL – lectins produced by entomopathogenic bacteria Photorhabdus luminescens and Photorhabdus asymbiotica. In XI European Congress of Entomology. 2018. info
• HYRŠL, Pavel, Pavel DOBEŠ, Jaroslav HAVLÍK, Jiří DANIHLÍK, Dalibor TITĚRA, Hana VINŠOVÁ a František KAMLER. Správná praxe a kvalita krmení včel pro úspěšné přezimování. 2018. Certifikovaná metodika ke stažení info
• JANČAŘÍKOVÁ, Gita, Josef HOUSER, Pavel DOBEŠ, Gabriel DEMO, Pavel HYRŠL a Michaela WIMMEROVÁ. Characterization of novel bangle lectin from Photorhabdus asymbiotica with dual sugar-binding specificity and its effect on host immunity. PLoS Pathogens. San Francisco: Public Library of Science, 2017, roč. 13, č. 8, s. 1-28. ISSN 1553-7366. Dostupné z: https://dx.doi.org/10.1371/journal.ppat.1006564. URL info
• PANZARINO, Onofrio, Pavel HYRŠL, Pavel DOBEŠ, Libor VOJTEK, Pasqua VERNILE, Giuseppe BARI, Roberto TERZANO, Matteo SPAGNUOLO a Enrico DE LILLO. Rank-based biomarker index to assess cadmium ecotoxicity on the earthworm Eisenia andrei. Chemosphere. Elsevier Science, 2016, roč. 145, February, s. 480-486. ISSN 0045-6535. Dostupné z: https://dx.doi.org/10.1016/j.chemosphere.2015.11.077. URL info
• ŘEŘICHA, Michal, Pavel DOBEŠ, Pavel HYRŠL a Michal KNAPP. Ontogeny of the immune system in harlequin ladybird, Harmonia axyridis. In 49th Annual Meeting of the Society for Invertebrate Pathology. 2016. info
• DOBEŠ, Pavel, Libor VOJTEK, Zuzana HRONCOVÁ, Jan TYL, Jiří KILLER, Peter ČERNOCH a Pavel HYRŠL. Honey bee immunity: Its modulation by dietary supplements and probiotics. In 49th Annual Meeting of the Society for Invertebrate Pathology. 2016. info
• IBRAHIM, Emad, Pavel DOBEŠ, Pavel HYRŠL a Dalibor KODRÍK. Defence reaction against nematobacterial infection in Drosophila melanogaster: a role for the adipokinetic hormone and adenosine. In 28th Conference of European Comparative Endocrinologists. 2016. info
• KUMAR, Atul, Petra SÝKOROVÁ, Gabriel DEMO, Pavel DOBEŠ, Pavel HYRŠL a Michaela WIMMEROVÁ. A Novel Fucose-Binding Lectin from Photorhabdus luminescens (PLL) with an Unusual Heptabladed beta-Propeller Tetrameric Structure. The Journal of Biological Chemistry. Bethesda: American Society for Biochemistry and Molecular Biology, 2016, roč. 291, č. 48, s. 25032-25049. ISSN 0021-9258. Dostupné z: https://dx.doi.org/10.1074/jbc.M115.693473. URL info
• HRONCOVÁ, Zuzana, Jaroslav HAVLÍK, Martin KAMLER, Dalibor TITĚRA, Pavel HYRŠL a Pavel DOBEŠ. Responses of honey bee colonies to supplemental feeding with probiotic bacteria. In 44th APIMONDIA International Apicultural Congress. 2015. info
• AREFIN, Badrul, Lucie KUČEROVÁ, Pavel DOBEŠ, Robert MARKUS, Hynek STRNAD, Zhi WANG, Pavel HYRŠL, Michal ŽUROVEC a Ulrich THEOPOLD. Genome-wide transcriptional analysis of Drosophila larvae infected by entomopathogenic nematodes shows involvement of complement, recognition and extracellular matrix proteins. Journal of Innate Immunity. Basel: Karger Publishers, 2014, roč. 6, č. 2, s. 192-204. ISSN 1662-811X. Dostupné z: https://dx.doi.org/10.1159/000353734. URL info
• VOJTEK, Libor, Pavel DOBEŠ, Ender BÜYÜKGÜZEL, Janne ATOSUO a Pavel HYRŠL. Bioluminescent assay for evaluating antimicrobial activity in insect haemolymph. European Journal of Entomology. 2014, roč. 111, č. 3, s. 335-340. ISSN 1210-5759. Dostupné z: https://dx.doi.org/10.14411/eje.2014.045. info
• VOJTEK, Libor, Pavel DOBEŠ, Lucie PROKOPOVÁ, Jitka VINKLEROVA, Michal VINKLER a Pavel HYRŠL. Chemiluminescent determination of reactive oxygen species using Pholasin luminophore in birds and insect phagocytes. In 18th International Symposium on Bioluminescence and Chemiluminescence. 2014. ISSN 1522-7235. info
• DOBEŠ, Pavel, Jakub BERKA, Jana HURYCHOVÁ, Libor VOJTEK a Pavel HYRŠL. Pathogenicity of nematobacterial complexes and its development. In International Congress on Invertebrate Pathology and Microbial Control & 47th Annual Meeting of the Society for Invertebrate Pathology. 2014. ISSN 1866-590X. info
• HYRŠL, Pavel, Pavel DOBEŠ, Libor VOJTEK a Jakub BERKA. Infection of honeybee larvae by entomopathogenic nematodes - natural model to study honeybee immunity. In Sixth European Conference of Apidology. 2014. ISBN 978-84-697-0855-2. info
• VOJTEK, Libor, Pavel DOBEŠ, Ender BÜYÜKGÜZEL a Pavel HYRŠL. Bioluminescence determination of antibacterial activity of Bombyx mori and Galleria mellonella haemolymph. In Insect pathogens and entomoparasitic nematodes. Darmstadt: IOBC-WPRS 2013, 2013, s. 333-338. ISBN 978-92-9067-268-5. info
• HYRŠL, Pavel, Pavel DOBEŠ, Badrul AREFIN, Lucie KUČEROVÁ, Robert MARKUS, Zhi WANG, Michal ŽUROVEC a Ulrich THEOPOLD. New insights to insect response to the infection by nematobacterial complex. In 14th Meeting of the IOBS/wprs Insect pathogens and entomoparasitic nematodes. 2013. ISBN 978-92-9067-268-5. info
• PAVLIŇÁK, David, Veronika ŠVACHOVÁ, Milan ALBERTI, Monika DUŠKOVÁ, Pavel HYRŠL, Libor VOJTEK, Pavel DOBEŠ a Helena NEJEZCHLEBOVÁ. Plasmachemical modifications of cellulose for biomedical application. In 5th Central European Symposium on Plasma Chemistry. 2013. ISBN 978-615-5270-04-8. info
• FLÖSSLER, Jaromír, Pavel DOBEŠ, Libor VOJTEK, Martin KAMLER, Jan TYL, Dalibor TITĚRA a Pavel HYRŠL. Bee immune system and methods evaluating its immune parameters. In XXXXIII. International Apicultural Congress Apimondia. 2013. info
• AREFIN, Badrul, Lucie KUČEROVÁ, Pavel DOBEŠ, Robert MARKUS, Hynek STRNAD, Zhi WANG, Pavel HYRŠL, Michal ŽUROVEC a Ulrich THEOPOLD. Functional studies on transcriptone profiles of Drosophila larvae infected by entomopathogenic nematodes. In Integrated Insect Immunology: From Basic Biology To Environmental Applications. 2013. info
• KUČEROVÁ, Lucie, Badrul AREFIN, Pavel DOBEŠ, Robert MARKUS, Hynek STRNAD, Zhi WANG, Pavel HYRŠL, Michal ŽUROVEC a Ulrich THEOPOLD. Genome-wide transcriptional analysis upon entomopathogenic nematode infection of Drosophila. In Integrated Insect Immunology: From Basic Biology To Environmental Applications. 2013. info
• DOBEŠ, Pavel, Zhi WANG, Robert MARKUS, Ulrich THEOPOLD a Pavel HYRŠL. An improved method for nematode infection assays in Drosophila larvae. Fly. Austin (USA): Landes Bioscience, 2012, roč. 6, č. 2, s. 75-79. ISSN 1933-6934. Dostupné z: https://dx.doi.org/10.4161/fly.19553. info
• PANZARINO, Onofrio, Pavel DOBEŠ, Libor VOJTEK, Karel VOSTAL, Giuseppe BARI, Enrico DE LILLO a Pavel HYRŠL. Wax moth (Galleria mellonella) as a bio-indicator model in ecotoxicological studies on cadmium. In Sborník abstraktů Zoologické dny Olomouc 2012. 2012. ISBN 978-80-87189-11-5. info
• THEOPOLD, Ulrich, Zhi WANG, Pavel DOBEŠ, Robert MARKUS a Pavel HYRŠL. Drosophila immune responses against entomopathogenic nematodes. In XXIV International Congress of Entomology. 2012. info
• SÝKOROVÁ, Petra, Pavel DOBEŠ, Pavel HYRŠL a Michaela WIMMEROVÁ. Novel pH dependent lectin from bioluminescent bacterium Photorhabdus luminescens. 2012. info
• HYRŠL, Pavel, Pavel DOBEŠ, Zhi WANG, Thomas HAULING, Christine WILHELMSSON a Ulrich THEOPOLD. Clotting factors and eicosanoids protect against nematode infections. Journal of Innate Immunity. 2011, roč. 3, č. 1, s. 65-70. ISSN 1662-811X. info
• THEOPOLD, Ulrich, Zhi WANG, Pavel DOBEŠ a Pavel HYRŠL. Hemolymph clotting and immunity. In 52nd Annual Drosophila Research Conference. 2011. info
• HYRŠL, Pavel, Pavel DOBEŠ, Zhi WANG a Ulrich THEOPOLD. Nematode infections are affected by insect clotting system. In 13th European Meeting IOBC/WPRS "Biological Control in IPM Systems". 2011. ISBN 978-92-9067-241-8. info
• WANG, Zhi, Christine WILHELMSSON, Pavel HYRŠL, Torsten G. LOOF, Pavel DOBEŠ, Martina KLUPP, Olga LOSEVA, Matthias MÖRGELIN, Jennifer IKLÉ, Richard M. CRIPPS, Heiko HERWALD a Ulrich THEOPOLD. Pathogen entrapment by transglutaminase - a conserved early innate immune mechanism. PLoS Pathogens. San Francisco: Public Library Science, 2010, roč. 6, č. 2, s. 1-9. ISSN 1553-7366. URL info
• VOJTEK, Libor, Pavel DOBEŠ a Pavel HYRŠL. Nematobacterial complex Heterorhabditis-Photorhabdus in immunity studies. In EMBO Young Scientists Forum 2010 Prague. 2010. info
• HYRŠL, Pavel, Pavel DOBEŠ, Zhi WANG a Ulrich THEOPOLD. Clotting factors and eicosanoids protect against nematode infections. In 43rd Annual Meeting SIP 2010 Turkey. 2010. info
• BENEŠOVÁ, Jana, Pavel DOBEŠ a Pavel HYRŠL. Developmental changes in phenol-oxidizing activity in the greater wax moth Galleria mellonella L. Bulletin of Insectology. Bologna, 2009, roč. 62, č. 2, s. 237-243. ISSN 1721-8861. info

2020/10/27