Curriculum Vitae

Person Identification

• Eva Šebestová (née: Chovancová)

Affiliation and Address

• Loschmidt Laboratories
  Department of Experimental Biology
  Faculty of Science, Masaryk University
  Kamenice 5/A13, 625 00 Brno, Czech Republic

Education and Academic Qualifications

• 2011: Ph.D., Environmental Chemistry, Faculty of Science, Masaryk University, Brno, Czech Republic
• 2004: M.Sc., Molecular Biology and Genetics, Faculty of Science, Masaryk University, Brno, Czech Republic

Employment Summary

• 2014-present: maternity leave
• 2012-2013: Research Centre for Toxic Compounds in the Environment, Faculty of Science, Masaryk University, Brno, Czech Republic
• 2009-2011: Department of Experimental Biology, Faculty of Science, Masaryk University, Brno, Czech Republic
• 2006-2008: National Centre for Biomolecular Research, Faculty of Science, Masaryk University, Brno, Czech Republic

Pedagogical Activities

• Bioinformatics - practice
• Structural biology
• Structural biology - practice
• Protein engineering

Research Activities

• molecular phylogenetics
• protein evolution
• bioinformatics
• protein engineering

Academical Stays

• 11/2005: CEMBM, International Institute of Molecular and Cell Biology, Warsaw, Poland
• 4/2005: EMBO Fellowship, International Institute of Molecular and Cell Biology, Warsaw, Poland
• 3-4/2003: Austria Grant, Institute of Cancer Research, University of Vienna, Vienna, Austria

Attended Courses

• 02/2010: Programmatic Access To Biological Databases (Perl), Hinxton, United Kingdom
• 03/2005: Molecular Phylogenetic Reconstruction Course, Tuebingen, Germany
• 09/2004: Summer School of Theoretical and Computational Chemistry, Prague, Czech Republic

Awards

• 2009: Award of the Dean of the Faculty of Science, Masaryk University

Publications

• PAVELKA, Antonín, Eva ŠEBESTOVÁ, Barbora KOZLÍKOVÁ, Jan BREZOVSKÝ, Jiří SOCHOR and Jiří DAMBORSKÝ. CAVER: Algorithms for Analyzing Dynamics of Tunnels in Macromolecules. IEEE/ACM Transactions on Computational Biology and Bioinformatics. IEEE Computer Society, 2016, vol. 13, No 3, p. 505 - 517. ISSN 1545-5963. Available from: https://dx.doi.org/10.1109/TCBB.2015.2459680. URL info
• LIŠKOVÁ, Veronika, David BEDNÁŘ, T. PRUDNIKOVA, P. REZACOVA, Táňa KOUDELÁKOVÁ, Eva ŠEBESTOVÁ, I., KUTA- SMATANOVÁ, Jan BREZOVSKÝ, Radka CHALOUPKOVÁ and Jiří DAMBORSKÝ. Balancing the Stability-Activity Trade-off by Fine-Tuning Dehalogenase Access Tunnels. ChemCatChem. 2015, vol. 7, No 4, p. 648-659. ISSN 1867-3880. Available from: https://dx.doi.org/10.1002/cctc.201402792. URL info
• BEDNÁŘ, David, Koen BEERENS, Eva ŠEBESTOVÁ, Jaroslav BENDL, S. KHARE, Radka CHALOUPKOVÁ, Zbyněk PROKOP, Jan BREZOVSKÝ, D. BAKER and Jiří DAMBORSKÝ. FireProt: Energy- and Evolution-Based Computational Design of Thermostable Multiple-Point Mutants. PLOS COMPUTATIONAL BIOLOGY. 2015, vol. 11, No 11, p. "nestrankovano", 20 pp. ISSN 1553-734X. Available from: https://dx.doi.org/10.1371/journal.pcbi.1004556. URL info
• KOZLÍKOVÁ, Barbora, Eva ŠEBESTOVÁ, Vilém ŠUSTR, Jan BREZOVSKÝ, Ondřej STRNAD, Lukáš DANIEL, David BEDNÁŘ, Antonín PAVELKA, Martin MANAK, Martin BEZDĚKA, Petr BENEŠ, Matúš KOTRY, Artur Wiktor GORA, Jiří DAMBORSKÝ and Jiří SOCHOR. CAVER Analyst 1.0: Graphic tool for interactive visualization and analysis of tunnels and channels in protein structures. Bioinformatics. Oxford University Press, 2014, vol. 30, No 18, p. 2684-2685. ISSN 1367-4803. Available from: https://dx.doi.org/10.1093/bioinformatics/btu364. info
• FOŘTOVÁ, Andrea, Eva ŠEBESTOVÁ, Veronika ŠTĚPÁNKOVÁ, Táňa KOUDELÁKOVÁ, Lenka PÁLKOVÁ, Jiří DAMBORSKÝ and Radka CHALOUPKOVÁ. DspA from Strongylocentrotus purpuratus: the First Biochemically Characterized Haloalkane Dehalogenase of Non-Microbial Origin. Biochimie. Elsevier, 2013, vol. 95, No 11, p. 2091-2096. ISSN 0300-9084. Available from: https://dx.doi.org/10.1016/j.biochi.2013.07.025. info
• BREZOVSKÝ, Jan, Eva ŠEBESTOVÁ, Artur Wiktor GORA, Antonín PAVELKA, Lada BIEDERMANNOVÁ and Jiří DAMBORSKÝ. Software tools for identification, visualization and analysis of protein tunnels and channels. BIOTECHNOLOGY ADVANCES. OXFORD: PERGAMON-ELSEVIER SCIENCE LTD, 2013, vol. 31, No 1, p. 38-49. ISSN 0734-9750. Available from: https://dx.doi.org/10.1016/j.biotechadv.2012.02.002. info
• KOUDELÁKOVÁ, Táňa, Radka CHALOUPKOVÁ, Jan BREZOVSKÝ, Zbyněk PROKOP, Eva ŠEBESTOVÁ, M. HESSELER, M. KHABIRI, M. PLEVAKA, D. KULIK, I. KUTA SMATANOVA, P. REZACOVA, R. ETTRICH, U.T. BORNSCHEUER and Jiří DAMBORSKÝ. Engineering Enzyme Stability and Resistance to an Organic Cosolvent by Modification of Residues in the Access Tunnel. Angewandte Chemie International Edition. Verlag Chemie, 2013, vol. 52, No 7, p. 1959-1963. ISSN 1433-7851. Available from: https://dx.doi.org/10.1002/anie.201206708. info
• CHOVANCOVÁ, Eva, Antonín PAVELKA, Petr BENEŠ, Ondřej STRNAD, Jan BREZOVSKÝ, Barbora KOZLÍKOVÁ, Artur Wiktor GORA, Vilém ŠUSTR, Martin KLVAŇA, Petr MEDEK, Lada BIEDERMANNOVÁ, Jiří SOCHOR and Jiří DAMBORSKÝ. CAVER 3.0: A Tool for the Analysis of Transport Pathways in Dynamic Protein Structures. PLoS Computational Biology. 2012, vol. 8, No 10, p. "nestránkováno", 12 pp. ISSN 1553-7358. Available from: https://dx.doi.org/10.1371/journal.pcbi.1002708. URL info
• BALONOVÁ, Lucie, B.F. MANN, Lukáš ČERVENÝ, W.R.Jr ALLEY, Eva CHOVANCOVÁ, Anna-Lena FORSLUND, E.N. SOLOMONSSON, A. FORSBEG, Jiří DAMBORSKÝ, L.V. NOVOTNÝ, Lenka HENRYCHOVÁ and Jiří STULÍK. Characterization of Protein Glycosylation in Francisella tularensis subsp. holarctica. Molecular and Cellurar Proteomic. Bethesda: Amer Soc Biochem Biol, 2012, vol. 11, No 7, p. 1-12. ISSN 1535-9476. Available from: https://dx.doi.org/10.1074/mcp.M111.015016. URL info
• BIEDERMANNOVÁ, Lada, Zbyněk PROKOP, Artur Wiktor GORA, Eva CHOVANCOVÁ, Mihály KOVÁCS, Jiří DAMBORSKÝ and Rebecca C. WADE. A Single Mutation in a Tunnel to the Active Site Changes the Mechanism and Kinetics of Product Release in Haloalkane Dehalogenase LinB. The Journal of Biological Chemistry. USA, 2012, vol. 287, No 34, p. 29062-29074. ISSN 0021-9258. Available from: https://dx.doi.org/10.1074/jbc.M112.377853. info
• DRIENOVSKÁ, Ivana, Eva CHOVANCOVÁ, Táňa KOUDELÁKOVÁ, Jiří DAMBORSKÝ and Radka CHALOUPKOVÁ. Biochemical Characterization of a Novel Haloalkane Dehalogenase from a Cold-Adapted Bacterium. APPLIED AND ENVIRONMENTAL MICROBIOLOGY. 2012, vol. 78, No 14, p. 4995-4998. ISSN 0099-2240. Available from: https://dx.doi.org/10.1128/AEM.00485-12. info
• KOUDELÁKOVÁ, Táňa, Eva CHOVANCOVÁ, Jan BREZOVSKÝ, Marta MONINCOVÁ, Andrea FOŘTOVÁ, Jiří JARKOVSKÝ and Jiří DAMBORSKÝ. Substrate Specificity of Haloalkane Dehalogenases. Biochemical Journal. 2011, vol. 435, No 435, p. 345-354. ISSN 0264-6021. Available from: https://dx.doi.org/10.1042/BJ20101405. info
• PAVELKA, Antonín, Eva CHOVANCOVÁ and Jiří DAMBORSKÝ. HotSpot Wizard: a Web Server for Identification of Hot Spots in Protein Engineering. NUCLEIC ACIDS RESEARCH. 2009, vol. 2009, No 37, p. 376-383. ISSN 0305-1048. URL info
• CHOVANCOVÁ, Eva, Jan KOSINSKI, Janusz M. BUJNICKI and Jiří DAMBORSKÝ. Phylogenetic Analysis of Haloalkane Dehalogenases. Proteins: Structure, Function, and Bioinformatics. 2007, vol. 67, No 2, p. 305-316. ISSN 0887-3585. URL info

2019/02/16