Curriculum Vitae

Curriculum Vitae

Person Identification

• Prof. Zbynek Prokop, Ph.D.
  born May 07, 1974 in Brno, Czech Republic

Affiliation and Address

• Loschmidt Laboratories, Institute of Experimental Biology and RECETOX, Faculty of Science, Masaryk University, Kamenice 5/A13, 625 00 Brno,Czech Republic

Professor

• Head, Laboratory of Kinetics and Microfluidics

Education and Academic Qualifications

• 2011: Prof., Environmental Chemistry, Masaryk University, Brno, Czech Republic
• 2011: Assoc. Prof., Environmental Chemistry, Masaryk University, Brno, Czech Republic
• 2001: Ph.D., Environmental Chemistry, Masaryk University, Brno, Czech Republic

Employment Summary

• 2000 – present: Faculty of Science, Masaryk University, Brno, Czech Republic
• 2013 – present: International Clinical Research Center, St. Anne's University Hospital Brno

Pedagogical Activities

• Bi7430 Molecular biotechnology
• Bi7430c Molecular biotechnology - practice
• Bi5111, Bi6009, Bi7623, Bi8624, Bi9625, Bi0626 Seminar of microbiology
• Bi9280 Summer school of protein engineering
• Bi7893 Seminar of Loschmidt laboratories
• Bi7894 Seminar of research teams in Loschmidt laboratories

Research Projects

• Enzyme Mechanism and Kinetics
• Enzyme-Based Technologies
• Protein Engineering
• Microfluidics

Academical Stays

• 4-5/2016: Technische Universität Wien, Austria
• 7-9/2014: ETH Zurich, Switzerland (EU-ERA Grant)
• 2/2012: University of Cambridge, United Kingdom
• 8/2011: University of Cambridge, United Kingdom
• 1/2010: Eötvös University, Hungary (EMBO Networking Grant)
• 2/2005: University of Hannover, Germany (NATO Collaborative Linkage Grant)
• 11/2004: EMBL Heidelberg, Germany (EMBO Networking Grant)
• 2-4/2004: University of Groningen, The Netherlands (EMBO Fellowship)
• 1-2/2002: University of Groningen, The Netherlands (NATO Science Fellowship)
• 10-11/2001: University of Groningen, The Netherlands (FEMS Fellowship)
• 3-5/1999: University of Ghent, Belgium (EU Socrates Student Exchange Program)

International Courses

• 2019: 13th New enzymology kinetics workshop, Brno, Czech Republic
• 2017: EMBO Course of Transient Kinetics, University of Kent, United Kingdom
• 2016: Time-resolved Fluorescence Spectroscopy, Berlin, Germany
• 2016: Time-resolved microscopy and correlation spectroscopy, Berlin, Germany
• 2014: Course on modern enzyme kinetics, University of Texas, Austin, USA
• 2011: EMBO Laboratory Management Course, DE-Leimen, Germany
• 2008: EMBO Course of Transient Kinetic Methods, University of Kent, United Kingdom
• 2006: Advanced Course on Biocatalysis, Technical University of Delft, The Netherlands
• 2002: Course on CD-Spectrometry, University of Warwick, United Kingdom
• 2001: Course on CD-Spectrometry, University of Budapest, Hungary

Membership in Scientific Organizations

• Czech Society or Biochemistry and Molecular Biology
• Czech Chemical Society
• Czechoslovak Society of Microbiology
• Czech Society for Analytical Cytology

Appreciation by Scientific Community

• 2015: The best technology paper in 2014, Environmental Science & Technology, ACS
• 2015: Werner von Siemens Award for Excellence in Innovation, Siemens
• 2014: The Best Academy/Industry Collaboration of The Year, 2nd Price, American Chamber of Commerce and Czech Association for Foreign Investment
• 2008: J. V. Kostir Prize for Biochemistry, Czech Society of Biochememistry and Molecular Biology
• 2005: Alfred Bader Prize for Bioorganic Chemistry, Czech Chemical Society
• 2005: Excellence in Inovation Award of the Rector of Masaryk University
• 2002: Award for the Young Czech and Slovak Microbiologist of the Year, Czechoslovak Microbiological Society
• 2000: First place, Student Poster Competition, 5-th Internation Symposium on Environmental Contamination in Central and Eastern Europe

Selected Publications

• MAZURENKO, Stanislav, Zbyněk PROKOP and Jiří DAMBORSKÝ. Machine Learning in Enzyme Engineering. ACS Catalysis. Washington, D.C.: American Chemical Society, 2020, vol. 10, No 2, p. 1210-1223. ISSN 2155-5435. Available from: https://dx.doi.org/10.1021/acscatal.9b04321. URL info
• JINDAL, Garima, Kateřina SLÁNSKÁ, Veselin KOLEV, Jiří DAMBORSKÝ, Zbyněk PROKOP and Arieh WARSHEL. Exploring the challenges of computational enzyme design by rebuilding the active site of a dehalogenase. Proceedings of the National Academy of Sciences of the United States of America. WASHINGTON: NATL ACAD SCIENCES, 2019, vol. 116, No 2, p. 389-394. ISSN 0027-8424. Available from: https://dx.doi.org/10.1073/pnas.1804979115. URL info
• KOKKONEN, Piia Pauliina, J. SYKORA, Zbyněk PROKOP, A. GHOSE, David BEDNÁŘ, M. AMARO, Koen BEERENS, Šárka NEVOLOVÁ, Michaela SLÁNSKÁ, Jan BREZOVSKÝ, Jiří DAMBORSKÝ and M. HOF. Molecular Gating of an Engineered Enzyme Captured in Real Time. Journal of the American Chemical Society. Washington: American Chemical Society, 2018, vol. 140, No 51, p. 17999-18008. ISSN 0002-7863. Available from: https://dx.doi.org/10.1021/jacs.8b09848. URL info
• MAZURENKO, Stanislav, Antonín KUNKA, Koen BEERENS, Christopher M. JOHNSON, Jiří DAMBORSKÝ and Zbyněk PROKOP. Exploration of Protein Unfolding by Modelling Calorimetry Data from Reheating. Scientific Reports. London: NATURE PUBLISHING GROUP, 2017, vol. 7, November, p. nestránkováno, 14 pp. ISSN 2045-2322. Available from: https://dx.doi.org/10.1038/s41598-017-16360-y. URL info
• GIELEN, Fabrice, Tomáš BURYŠKA, Liisa VAN VLIET, Maren BUTZ, Jiří DAMBORSKÝ, Zbyněk PROKOP and Florian HOLLFELDER. Interfacing Microwells with Nanoliter Compartments: A Sampler Generating High-Resolution Concentration Gradients for Quantitative Biochemical Analyses in Droplets. Analytical Chemistry. 2015, vol. 87, No 1, p. 624-632. ISSN 0003-2700. Available from: https://dx.doi.org/10.1021/ac503336g. URL info
• DVOŘÁK, Pavel, Šárka BIDMANOVÁ, Jiří DAMBORSKÝ and Zbyněk PROKOP. Immobilized Synthetic Pathway for Biodegradation of Toxic Recalcitrant Pollutant 1,2,3-Trichloropropane. Environmental Science & Technology. 2014, vol. 48, No 12, p. 6859-6866. ISSN 0013-936X. Available from: https://dx.doi.org/10.1021/es500396r. info
• SYKORA, J., Jan BREZOVSKÝ, Táňa KOUDELÁKOVÁ, M. LAHODA, Andrea FOŘTOVÁ, T. CHERNOVETS, Radka CHALOUPKOVÁ, Veronika ŠTĚPÁNKOVÁ, Zbyněk PROKOP, I. KUTA SMATANOVA, M. HOF and Jiří DAMBORSKÝ. Dynamics and Hydration Explain Failed Functional Transformation in Dehalogenase Design. Nature Chemical Biology. 2014, vol. 10, No 6, p. 428-430. ISSN 1552-4450. info
• PROKOP, Zbyněk, Yukari SATO, Jan BREZOVSKÝ, Tomáš MOZGA, Radka CHALOUPKOVÁ, Táňa KOUDELÁKOVÁ, Petr JEŘÁBEK, Veronika ŠTĚPÁNKOVÁ, Rio NATSUME, J.G.E. LEEWEN, D,B. JANSSEN, J. FLORIAN, Yuji NAGATA, T. SENDA and Jiří DAMBORSKÝ. Enantioselectivity of Haloalkane Dehalogenases and its Modulation by Surface Loop Engineering. Angewandte Chemie International Edition. Wiley-VCH Verlag GmbH & Co. KGaA, Weinhe, 2010, vol. 49, No 35, p. 6111-6115. ISSN 1433-7851. URL info
• PROKOP, Zbyněk, Andrea FOŘTOVÁ, Radka CHALOUPKOVÁ, Martina PAVLOVÁ, Eva CHOVANCOVÁ, Jan BREZOVSKÝ, Martin KLVAŇA, Táňa KOUDELÁKOVÁ, Tomáš MOZGA, Antonín PAVELKA, Pavel DVOŘÁK, Monika STRAKOVÁ and Jiří DAMBORSKÝ. Engineering of Biocatalysts by Modification of Access Tunnels. In Novel Enzymes. 2010. info
• PROKOP, Zbyněk, Marta MONINCOVÁ, Radka CHALOUPKOVÁ, Martin KLVAŇA, Yuji NAGATA, Dick B. JANSSEN and Jiří DAMBORSKÝ. Catalytic mechanism of the haloalkane dehalogenase LinB from Sphingomonas paucimobilis UT26. Journal of Biological Chemistry. 2003, vol. 278, No 46, p. 45094-45100. ISSN 0021-9258. URL info

2020/06/18