MNBS081c Biostatistics - practice

Faculty of Medicine
spring 2025
Extent and Intensity
0/1/0. 1 credit(s). Type of Completion: z (credit).
In-person direct teaching
Teacher(s)
prof. RNDr. Ladislav Dušek, Ph.D. (lecturer)
RNDr. Jiří Jarkovský, Ph.D. (lecturer)
RNDr. Michal Svoboda (lecturer)
RNDr. Danka Haruštiaková, Ph.D. (seminar tutor)
MVDr. Halina Matějová (assistant)
Guaranteed by
prof. RNDr. Ladislav Dušek, Ph.D.
Institute of Biostatistics and Analyses – Other Departments for Educational and Scientific Research Activities – Faculty of Medicine
Supplier department: Institute of Biostatistics and Analyses – Other Departments for Educational and Scientific Research Activities – Faculty of Medicine
Prerequisites
none - basic course
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
The course is basic introduction into practical data analysis. The course accompanies lectures of MNBS081 and shows the computation of presented methods on PC using statistical software (descriptive statistics, one sample and two sample tests, categorical data analysis, ANOVA, correlation analysis, data visualisation).
Learning outcomes
Students will be able after the course to use the folowing data analysis methods:
- Descriptive statistics, data visualisation.
- Distribution of continuous variables.
- One sample tests - parametrical and nonparametrical.
- Two sample tests - parametrical and nonparametrical.
- Analysis of variance (ANOVA), Kruskal-Wallis test.
- Analysis of contingency table.
- Corelation, linear regression.
Syllabus
  • 1. Data processing – principles of correct data manipulation. MS Office Excel – appropriate tool for storing, organizing, and manipulating data.
  • 2. Introduction to statistics. Data types in medicine and biology; nominal, ordinal, continuous variable. Visualization of quantitative and qualitative (categorical) variables.
  • 3. Descriptive statistics. Mean, median, quantiles, variance. Frequency table.
  • 4. Distribution of continuous variables. Normal distribution, log-normal distribution.
  • 5. Principles of hypotheses testing. Definition of null and alternative hypothesis. Significance level. Type I and type II error.
  • 6. Graphical examining of normal distribution (histogram, normal-probability plot). Shapiro-Wilk test – a test of normality.
  • 7. Parametrical tests: t-tests. One-sample t-test, two-sample t-test, t-test for dependent samples.
  • 8. Analysis of variance ANOVA.
  • 9. Nonparametrical tests: one-sample Wilcoxon test, Mann-Whitney U test, Wilcoxon test for dependent samples, Kruskal-Wallis test.
  • 10. Definition of contingency table and its analysis: Pearson chi-square test, Fisher exact test, McNemar test.
  • 11. Correlation. Pearson correlation coefficient, Spearman correlation coefficient.
  • 12. Introduction to regression analysis. Linear regression.
Teaching methods
Practical training using computers
Assessment methods
Exam based on correct application of statistical methods.
Language of instruction
Czech
Follow-Up Courses
Further comments (probably available only in Czech)
The course is taught annually.
The course is taught: in blocks.
Information on the extent and intensity of the course: 15.
The course is also listed under the following terms Spring 2011, Spring 2012, Spring 2013, Spring 2014, Spring 2015, Spring 2016, Spring 2017, Spring 2018, spring 2019, spring 2020, spring 2021, spring 2022, spring 2023, spring 2024.
  • Enrolment Statistics (spring 2025, recent)
  • Permalink: https://is.muni.cz/course/med/spring2025/MNBS081c