F1FM1_14 Pharmacogenomics

Faculty of Pharmacy
Autumn 2022
Extent and Intensity
2/0/0. 3 credit(s). Type of Completion: zk (examination).
Taught in person.
Teacher(s)
PharmDr. Mgr. Alžběta Kružicová, Ph.D. (lecturer)
Guaranteed by
PharmDr. Mgr. Alžběta Kružicová, Ph.D.
Department of Pharmacology and Toxicology – Departments – Faculty of Pharmacy
Timetable
Mon 14:55–16:35 44-037
Prerequisites (in Czech)
FAKULTA ( FaF ) || OBOR ( MUSFaF )
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.

The capacity limit for the course is 25 student(s).
Current registration and enrolment status: enrolled: 5/25, only registered: 0/25
fields of study / plans the course is directly associated with
Course objectives
Pharmacogenomics deals with the study of genetic sources of drug response variability. In this subject the students have chance to learn basic genetic factors which determine both drug effectiveness and side effects of this drug. Then genetic factors adjudicate the successfullness of chosen pharmacotherapy.
Learning outcomes
Pharmacogenomics deals with the study of genetic sources of drug response variability. In this subject the students have chance to learn basic genetic factors which determine both drug effectiveness and side effects of this drug. Then genetic factors adjudicate the successfullness of chosen pharmacotherapy.
Syllabus
  • 1. Introduction to the Pharmacogenomics. Overview of the subject, basic terms 2. Basics of Human Genetics/Genomics 3. Genetics and Human Diseases 4. Genetic polymorphism - clinical relevance 5. Pharmacogenetics and Pharmacokinetics I 6. Pharmacogenetics and Pharmacokinetics II 7. Pharmacogenetics and Pharmacodynamics I 8. Pharmacogenetics and Pharmacodynamics II 9. Public/National Holiday - The Lecture is canceled 10. Pharmacogenetics and Pharmacodynamics III 11. Modern methods in Pharmacogenomics, bioinformatics 12. Consultation 13. Exam (test of knowledge)
Literature
    recommended literature
  • Strachan a kol. Human Molecular Genetics 3. ISBN 0-8153-4184-9. info
  • Nussbaum a kol. Klinická genetika. ISBN 80-7254-475-6. info
  • Šmarda J. a kol. Metody molekulární biologie. ISBN 80-210-3841-1. info
  • Altman a kol. Principles of Pharmacogenetics and Pharmacogenomics. 2012. ISBN 978-0521885379. info
  • Innocenti Federico a kol. Genomics and Pharmacogenomics in Anticancer Drug Development and Clinical Response. 2008. ISBN 978-1588296467. info
  • Innocenti Federico. Pharmacogenomics. 2005. ISBN 9781588294401. info
Teaching methods
Lectures
Assessment methods
final exam
Language of instruction
Czech
Further Comments
Study Materials
The course can also be completed outside the examination period.
Teacher's information
Subject is finished by exam (multiple choice test).
The course is also listed under the following terms Autumn 2023, Autumn 2024.
  • Enrolment Statistics (Autumn 2022, recent)
  • Permalink: https://is.muni.cz/course/pharm/autumn2022/F1FM1_14