FDGFG_FAF Pharmacognosy and Phytochemistry

Faculty of Pharmacy
Spring 2020
Extent and Intensity
1/1/0. 30 credit(s). Type of Completion: zk (examination).
Teacher(s)
doc. PharmDr. Renata Kubínová, Ph.D. (lecturer)
prof. RNDr. Václav Suchý, DrSc., dr. h.c. (lecturer)
prof. PharmDr. Karel Šmejkal, Ph.D. (lecturer)
Guaranteed by
prof. PharmDr. Karel Šmejkal, Ph.D.
Faculty of Pharmacy
Prerequisites
The knowledge of organic chemistry, inorganic chemistry, physical chemistry, phytochemistry, pharmacology.
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
Learning outcomes of the course aim on the subject of focusing the students of DSP on the problems of drugs and auxiliary substances of natural origin used in human and veterinary medicine. Pharmacognosy focuses on the study of bioactive natural materials sources and the possibilities of their biotechnological acquisition. The DSP student will learn in detail the interrelationships and the conditionality of the production of secondary metabolites, the mechanism of their effect and the possibilities of practical use. Within the study of phytochemistry, the subject describes substances, defines their structure in relation to biological properties, deals with their qualitative and quantitative analysis and biological activity. It uses the procedures and methods described in

scientific and professional publications with an emphasis on the knowledge of science and research contained in world databases containing knowledge from scientific publications and is necessary to increase the student's ability to gain knowledge from the described field of knowledge in the research texts.
Learning outcomes
From the point of view of professional knowledge and skills, the graduate has the knowledge of Pharmacognosy and areas related to the emphasis on knowledge in national and world scientific databases and other scientific and professional literature and should be able to present them to the professional public.
Syllabus
  • The content of the subject is the issue of pharmaceuticals and auxiliary substances of natural origin used in human and veterinary medicine. Pharmacognosy deals with the search and study of the sources of bioactive natural substances and the possibilities of their extraction, separation, identification and biotechnological preparation. It explains the interrelationship and the conditionality of the formation of secondary metabolites, the mechanism of their effect and possibilities of practical use. Within the framework of phytochemistry, the subject also describes the content of substances, defines their structure, which determines the biological properties, deals with their qualitative and quantitative analysis and biological activity. It uses the procedures and methods described in scientific and professional publications with an emphasis on the knowledge of science and research contained in world databases containing knowledge from scientific publications and is necessary to increase the student's ability to gain knowledge from the described field of knowledge in the research texts.
    Syllabus of the course:
    Natural medicines and raw materials for their preparation. Phytopharmaceuticals, phytotherapy. From plants to phytopharmaceuticals. Registration requirements. Homeopathy, natural healing.
    Types of natural medicines, requirements for their quality. Systems for separating drugs of biogenic origin.
    Methodology of pharmacognosis.
    Natural medicines in relation to Pharmacopoeia and mass-produced medicinal products. Pharmacological methods for drug evaluation. Normatives.
    Biosynthesis of natural substances, primary and secondary metabolites, precursors, interactions.
    Sugars and their derivatives. Mono-, oligo- and polysaccharides (starches, mucilages, gums), specific sugars. Glycoconjugates.
    Glycosides, essential oils, steroids, lipids, mustards, alkaloids, tannins, flavonoids, dyes, substances with hormonal action, proteins, peptides, vitamins.
    Antibiotics, macrolides, cytostatic, fungal components, animal drugs.
    Natural substances derived from shikimic acid.
    Natural substances derived from acetic acid.
    Natural substances derived from mevalonic acid.
    Natural substances derived from amino acids.
    Pharmacotherapeutic groups including natural substances.
    Pharmacokinetics, elimination, interaction potential.
    Toxicity of natural substances.
    The subject is taught in the form of personal consultations, self-study and dialogue with the teacher.
    Teaching includes participation in educational events organized by the Department of Natural Drugs.
Literature
    recommended literature
  • European Pharmacopoeia (Ph. Eur.) 9th. info
  • Samuelsson G., Bohlin L. Drugs of Natural Origin. A Treatise of Pharmacognosy. 7th revised edition. 2015. info
  • Wichtl M. Herbal Drugs and Phytopharmaceuticals. 2002. info
  • Dewick P.M. Medicinal Natural Products. 2002. info
  • Bruneton J. Pharmacognosy, Phytochemistry, Medicinal Plants. 1999. info
Teaching methods (in Czech)
Dialogická (diskuze, rozhovor, brainstorming)
Demonstrace
Assessment methods (in Czech)
Ústní zkouška
Language of instruction
Czech
Further comments (probably available only in Czech)
The course can also be completed outside the examination period.
Teacher's information
Deep knowledge of the subject Pharmacognosy, with a special focus on areas close to the dissertation.
  • Enrolment Statistics (recent)
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