FAOC1_15 Organic Chemistry

Faculty of Pharmacy
Spring 2024
Extent and Intensity
5/4/0. 10 credit(s). Type of Completion: zk (examination).
Teacher(s)
doc. Ing. Pavel Bobáľ, CSc. (lecturer)
doc. Ing. Pavel Bobáľ, CSc. (seminar tutor)
Mgr. Hana Pížová, Ph.D. (seminar tutor)
PharmDr. Jan Otevřel, Ph.D. (alternate examiner)
Mgr. Aleš Kroutil, Ph.D. (seminar tutor)
Guaranteed by
doc. Ing. Pavel Bobáľ, CSc.
Department of Chemical Drugs – Departments – Faculty of Pharmacy
Timetable
Tue 8:30–10:35 44-249, Wed 8:30–10:35 44-249
  • Timetable of Seminar Groups:
FAOC1_15/01: Tue 11:00–14:20 44-342, P. Bobáľ, H. Pížová
Prerequisites
The knowledge of basics of inorganic chemistry.
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
Organic chemistry gives students information about the fundamentals of organic compounds structure, their reactions, and underling reaction mechanism. Organic chemistry is essential for many other disciplines, such as biochemistry, analytical chemistry, pharmaceutical chemistry, physiology, pharmacology and other health and biological studies. Close attention is paid to the interrelation between organic chemistry and these disciplines.
Learning outcomes
Understanding of fundamentals of organic chemistry, understanding of structure and reactivity of organic compounds, knowledge of the basis of IUPAC nomenclature of organic compounds and principals of stereochemistry.
Syllabus
  • 1 Structure and Bonding
    2 Polar Covalent Bonds, Acids and Bases
    3 Organic Compounds: Alkanes and Their Stereochemistry
    4 Organic Compounds: Cycloalkanes and Their Stereochemistry
    5 An Overview of Organic Reactions
    6 Alkenes: Structure Reactivity and reactions
    7 Alkynes: An Introduction to Organic Synthesis
    8 Stereochemistry at Tetrahedral Centers
    9 Organohalides, Reactions of Alkyl Halides: Nucleophilic Substitutions and Eliminations
    10 Structure Determination: MS, IR and NMR
    11 Conjugated Compounds and Ultraviolet Spectroscopy
    12 Benzene and Aromaticity, Chemistry of Benzene: Electrophilic Aromatic Substitution
    13 Alcohols and Phenols
    14 Ethers and Epoxides, Thiols and Sulfides
    15 Carbonyl Compounds, Aldehydes and Ketones: Nucleophilic Addition Reactions
    16 Carboxylic Acids and Nitriles
    17 Carboxylic Acid Derivatives: Nucleophilic Acyl Substitution Reactions
    18 Carbonyl Alpha-Substitution Reactions, Carbonyl Condensation Reactions
    19. Carbonic acid derivatives
    20 Nitrogen Compounds
    21 Organometallic Compounds
    22 Heterocycles: 3-,4-,7- and more membered
    23 Heterocycles: 5- and 6-membered
    24 Photochemistry, Orbitals and Organic Chemistry: Pericyclic Reactions
    25 Biomolecules: Carbohydrates
    26 Biomolecules: Amino Acids, Peptides, and Proteins
    27 Biomolecules: Lipids
    28 Biomolecules: Nucleic Acids
    29 Synthetic Polymers
    30 Nomenclature of Organic Compounds
Literature
    required literature
  • McMurry J. Organic Chemistry International Ed., 8th Revised Ed. Cengage Learning, Inc. (United States), 2011. ISBN 9780840054531. info
  • Williamson K.L., Masters K.M. Techniques Labs for Macroscale and Microscale Organic Experiments, 6th Ed. Brooks/Cole, Cangage Learning, 2011. ISBN 978-1-111-43041-2. info
Teaching methods
Lectures - on-line - MS Teams Lab. excercises - full-time
Assessment methods
Conditions for granting credit from lab. exercises: - Completion of all laboratory tasks; participation according to the MU study regulations, - Elaboration and submission of protocols from laboratory exercises (writing by hand according to the available template), including submission of prepared substances and their corresponding characterization, - At least 60% success in regular weekly tests. The tests will focus not only on checking practical skills, but also theoretical ones given at least one week in advance. Conditions for successful completion of the exam: - Credit from laboratory exercise, - Completion of the written part of the exam in the given term with at least 60% success
Language of instruction
English
Further comments (probably available only in Czech)
Study Materials
The course can also be completed outside the examination period.
Teacher's information
https://moodlinka.ics.muni.cz
Credits can be earned only upon completion of laboratory course work (100% attendance + compound characterization + lab reports). Students must achieve a grade point average of 60% or greater on weekly tests at the beginning of lab. exercises. ¨

Student must achieve a grade point average of 60% or greater on the final written exam.
The course is also listed under the following terms Spring 2020, Spring 2021, Spring 2022, Spring 2023, Spring 2025.
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