FDTSM_FAF Special Analytical Methods in Medicaments Manufacture and Quality Control

Faculty of Pharmacy
Spring 2024
Extent and Intensity
1/1/0. 25 credit(s). Type of Completion: zk (examination).
Teacher(s)
doc. Mgr. Jan Muselík, Ph.D. (lecturer)
Guaranteed by
doc. Mgr. Jan Muselík, Ph.D.
Faculty of Pharmacy
Prerequisites (in Czech)
FAKULTA(FaF)
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
Expanding the knowledge of the student focusing on modern methods used in pharmaceutical development as well as quality control, obtained mainly from world databases containing knowledge from scientific publications especially of foreign research experts and institutions and increasing the ability of the student to process this knowledge into research texts focusing on the content of the study program.
Learning outcomes
After completing the course, the student will be able to: - summarize the main methods used in the analysis of solid dosage forms; - understand the theoretical basis of these methods; - describe the main applications of these methods in pharmaceutical research and industry.
Syllabus
  • 1 Middle and near infrared spectroscopy, principles, instrumentation, measurement techniques. Lecturer: doc. Mgr. Jan Muselík, Ph.D. 2 Applications of infrared spectroscopy, evaluation of spectra Lecturer: doc. Mgr. Jan Muselík, Ph.D. 3 Dissolution test, methods of determination of active compound content (UV/VIS spectrophotometry). Lecturer: doc. Mgr. Jan Muselík, Ph.D. 4 Methods of determination of active compound content (HPLC). Lecturer: doc. Mgr. Jan Muselík, Ph.D 5 Light microscopy. Lecturer: Mgr. Sylvie Pavloková, Ph.D. 6 Scanning, transmission and environmental electron microscopy. Lecturer: Mgr. Sylvie Pavloková, Ph.D. 7 Scanning probe microscopy. Lecturer: Mgr. Sylvie Pavloková, Ph.D. 8 Methods of particle size determination (light microscopy, sedimentation analysis, sieve analysis, Coulter counter). Lecturer: Mgr. Sylvie Pavloková, Ph.D. 9 Methods of particle size determination - laser diffraction Lecturer: Mgr. Sylvie Pavloková, Ph.D. 10 X-ray analysis, instrumentation and applications in pharmaceutical technology. Lecturer: doc. Mgr. Jan Muselík, Ph.D. 11 Methods of thermal analysis (differential thermal analysis - DTA, thermogravimetry - TGA). Lecturer: doc. Mgr. Jan Muselík, Ph.D. 12 Methods of thermal analysis (differential scanning calorimetry - DSC). Lecturer: doc. Mgr. Jan Muselík, Ph.D.
Literature
    recommended literature
  • Muselík J. Vybrané instrumentální metody ve farmaceutické technologii. ISBN 978-80-7305-640-7. info
  • MUSELÍK, Jan, Jakub VYSLOUŽIL and Kateřina KUBOVÁ. Modern Instrumental Methods in Solid Dosage Form Analysis. 1st ed. Brno: Masarykova univerzita, 2021, 231 pp. ISBN 978-80-210-9723-0. info
Teaching methods
consultation
Assessment methods
oral exam
Language of instruction
Czech
Further Comments
The course can also be completed outside the examination period.
The course is taught each semester.
The course is also listed under the following terms Spring 2020, Autumn 2020, Spring 2021, Autumn 2021, Spring 2022, Autumn 2022, Spring 2023, Autumn 2023, Autumn 2024, Spring 2025.
  • Enrolment Statistics (Spring 2024, recent)
  • Permalink: https://is.muni.cz/course/pharm/spring2024/FDTSM_FAF