PřF:C5241 Analysis of Org.Compounds I - Course Information
C5241 Analysis of Organic Compounds I
Faculty of ScienceAutumn 2005
- Extent and Intensity
- 2/0/0. 2 credit(s) (fasci plus compl plus > 4). Recommended Type of Completion: zk (examination). Other types of completion: k (colloquium).
- Teacher(s)
- doc. RNDr. Bc. Jiří Pazourek, Ph.D. (lecturer)
- Guaranteed by
- prof. RNDr. Josef Havel, DrSc.
Chemistry Section – Faculty of Science - Timetable
- Mon 18:00–19:50 02004
- Prerequisites
- C2021 - Organic chemistry I C3100 + C4050 Analytical chemistry (at least C1660)
- Course Enrolment Limitations
- The course is also offered to the students of the fields other than those the course is directly associated with.
- fields of study / plans the course is directly associated with
- Analytical Chemistry (programme PřF, M-CH)
- Analytical Chemistry (programme PřF, N-CH)
- Inorganic Chemistry (programme PřF, M-CH)
- Biochemistry (programme PřF, M-CH)
- Chemistry (programme PřF, M-CH)
- Environmental Chemistry (programme PřF, M-CH)
- Macromolecular Chemistry (programme PřF, M-CH)
- Organic Chemistry (programme PřF, M-CH)
- Upper Secondary School Teacher Training in Chemistry (programme PřF, M-CH)
- Upper Secondary School Teacher Training in Chemistry (programme PřF, M-SS)
- Course objectives
- Classical organic analysis = characteristic physical properties of organic compounds, elemental analysis of organic compounds, analytical identification and determination of important functional groups of organic compounds, mainly by colour reactions in solution. Interpretation of spectra of simple organic compounds obtained by instrumental methods: UV-VIS, IR, NMR, MS.
- Syllabus
- Characteristics of analysis of organic compounds. The methodology of the analysis, development and trends. Determination of physical constants: melting and boiling point, refractivity, optical activity, partition coefficients of extraction, molecular weight, spectral constants. Elemental analysis. Sample decomposition, detection and determination of C, H, O, N, Cl, Br, I, S, P, F. Automatic methods of elemental analysis. Functional groups identification: classes of dissolution, classification reactions for carbohydrates, alcohols, phenols, aldehydes, ketons, carboxylic acids, acid anhydrides, esters, amides, imides, ethers, epoxides, peroxides, amines, nitriles, isonitriles, nitro-, nitroso-, azo-, azoxy-, hydrazo- and diazo- compounds, thiols, sulphonic and sulphinic acids, halogenic compounds. Determination of organic compounds based on their functional groups reactions. Determination of active hydrogen, determination of hydroxy-, carbonyl-, carboxyl-, amino-, nitro-, nitroso-, thio- a halogeno-compounds. Liquid-liquid extraction, thin layer chromatography (TLC). Instrumental methods of organic analysis - principles (gas chromatography (GC), liquid chromatography (LC), spectroscopy, optical rotation dispersion (ORD), nuclear magnetic resonance (NMR) and mass spectrometry (MS)). Spectra interpretation in organic analysis UV-VIS spectroscopy: sigma and pi orbitals, chromophores, allowed and disallowed electron transitions, Woodward-Fieser rules, examples. Infra red (IR) spectroscopy: models of fundamental and normal vibration, procedure of IR spectra interpretation with tables of characteristic vibrations. Nuclear magnetic resonance (NMR): chemical shift, first order spectra and their interpretation, spin interaction constant, decoupling, examples. Mass spectrometry (MS): specifics of the spectra, determination of summary formula from the natural nuclides distribution, fragments analysis of organic molecules, ionradical, molecular ion, empirical rules, carbcation stability, nitrogen rules, examples.
- Literature
- STRÁNSKÝ, Zdeněk. Analýza organických sloučenin. 1. vyd. Olomouc: Univerzita Palackého, 1981, 235 s. info
- STRÁNSKÝ, Zdeněk. Analýza organických sloučenin b. 1. vyd. Olomouc: Univerzita Palackého, 1981, 235 s. info
- KALOUS, Vítěz. Jak moderní chemie zkoumá strukturu molekul. 1. vyd. Praha: SNTL - Nakladatelství technické literatury, 1983, 150 s. URL info
- HOLZBECHER, Záviš. Analytická chemie. 2., přeprac. vyd. Praha: SNTL - Nakladatelství technické literatury, 1974, 506 s. info
- STUŽKA, Václav. Instrumentální metody chemické analysy. 1. vyd. Olomouc: Univerzita Palackého, 1974, 111 s. info
- STUŽKA, Václav. Instrumentální metody chemické analysy. 1. vyd. Olomouc: Univerzita Palackého, 1975, 128 s. info
- STUŽKA, Václav. Instrumentální metody chemické analýzy. 1. vyd. Olomouc: Univerzita Palackého, 1976, 146 s. info
- Assessment methods (in Czech)
- přednáška zkouška
- Language of instruction
- Czech
- Follow-Up Courses
- Further comments (probably available only in Czech)
- The course can also be completed outside the examination period.
The course is taught annually. - Teacher's information
- http://www.chemi.muni.cz/~pazourek/
- Enrolment Statistics (Autumn 2005, recent)
- Permalink: https://is.muni.cz/course/sci/autumn2005/C5241