C8967 15N NMR Spectroscopy
Faculty of ScienceAutumn 2007 - for the purpose of the accreditation
- Extent and Intensity
- 1/0/0. 1 credit(s) (plus 1 credit for an exam). Type of Completion: k (colloquium).
- Teacher(s)
- prof. RNDr. Radek Marek, Ph.D. (lecturer)
- Guaranteed by
- prof. RNDr. Radek Marek, Ph.D.
National Centre for Biomolecular Research – Faculty of Science - Prerequisites (in Czech)
- Target group: advanced undergraduates and Ph.D. students Prerequisites: basic knowledge of high-resolution NMR spectroscopy
- Course Enrolment Limitations
- The course is offered to students of any study field.
- Course objectives (in Czech)
- Nitrogen atom is an important element in organic, organometallic, and inorganic chemistry as well as in biochemistry. NMR spectroscopy is a sensitive method for studying bonding and electronic properties of nitrogen atom. Various aspects of NMR spectroscopy of N-15 isotope will be discussed.
- Syllabus
- 1.-2. Basics of NMR spectroscopy: general considerations, 14N vs. 15N, natural abundance, line shape, relaxation, NOE, polarization transfer, 1H-15N correlation experiments 3.-4. NMR in solution: 15N NMR chemical shift, X-15N coupling constants, magnetic field gradients, optimization of experiments, probeheads 5.-6. Solid-state NMR: 15N chemical shift tensor (CST), chemical shift anisotropy, principal components of CST, 15N CP/MAS, 1H-15N dipolar couplings, interatomic distances 7.-8. Quantum chemical calculations of 15N NMR parameters: geometry, chemical shielding, indirect spin-spin couplings 9.-10. Structural problems: regioisomerism, rotational isomerism, tautomerism, protonation, complexation, N-oxidation 11.-14: Applications: Interpretation of high-resolution 1H-15N NMR spectra, practical aspects
- Literature
- MAREK, Radek and Antonín LYČKA. 15N NMR Spectroscopy in Structural Analysis. Current Organic Chemistry. BR Hilversum: Bentham Science Publishers, 2002, vol. 6, No 1, p. 35-66. ISSN 1385-2728. Available from: https://dx.doi.org/10.2174/1385272023374643. DOI: 10.2174/1385272023374643 info
- MAREK, Radek, Antonín LYČKA, Erkki KOLEHMAINEN, Elina SIEVÄNEN and Jaromír TOUŠEK. 15N NMR Spectroscopy in Structural Analysis: An Update (2001-2005). Current Organic Chemistry. Hilversum: Bentham Science Publishers Ltd., 2007, vol. 11, No 13, p. 1154-1205. ISSN 1385-2728. Available from: https://dx.doi.org/10.2174/138527207781662519. DOI: 10.2174/138527207781662519 info
- Language of instruction
- English
- Further comments (probably available only in Czech)
- The course is taught once in two years.
The course is taught: in blocks.
- Enrolment Statistics (Autumn 2007 - for the purpose of the accreditation, recent)
- Permalink: https://is.muni.cz/course/sci/autumn2007-forthepurposeoftheaccreditation/C8967