C2132 Introduction to bioinformatics - seminar

Faculty of Science
Spring 2025
Extent and Intensity
0/1/0. 1 credit(s). Type of Completion: z (credit).
In-person direct teaching
Teacher(s)
prof. RNDr. Michaela Wimmerová, Ph.D. (lecturer)
Mgr. Lenka Malinovská, Ph.D. (lecturer)
Mgr. Josef Houser, Ph.D. (lecturer)
Mgr. Tereza Buráňová (assistant)
Guaranteed by
prof. RNDr. Michaela Wimmerová, Ph.D.
National Centre for Biomolecular Research – Faculty of Science
Supplier department: National Centre for Biomolecular Research – Faculty of Science
Prerequisites
Basic knowledge of biomacromolecules (proteins, nucleic acids).
Course Enrolment Limitations
The course is offered to students of any study field.
Course objectives
The goal of this seminar is practical exercising of knowledges obtained in the course C2131 Introduction to bioinformatics.
Learning outcomes
At the end of the course students should be able to: 1) Predict genes in DNA sequence. 2) Work with DNA and protein sequences. 3) Use prediction tools. 4) Use visualization tools.
Syllabus
  • 1) Main sources of bioinformatic data.
    2) Genetic information, genetic code, codon table. DNA translation.
    3) Amino acid nomenclature, single-letter and three-letter abbreviations.
    4) Alignment. Matrix. Local and global alignment.
    5) Identification of ORF within sequence.
    6) Identification of palindromes.
    7) RNA.
    8) Distance matrix. Creation of phylogenetic trees.
    9) Basic protein properties. Prediction tools.
    10) Protein secondary structure prediction.
    11) Bioinformatic tools for glycosylation prediction.
    12-13) Visiting laboratories in the MUNI campus area.
Teaching methods
Group exercises, homeworks.
Assessment methods
Final written test.
Language of instruction
Czech
The course is also listed under the following terms Spring 2020, Spring 2021, Spring 2022, Spring 2023, Spring 2024.
  • Enrolment Statistics (recent)
  • Permalink: https://is.muni.cz/course/sci/spring2025/C2132