IC167 Open Shell Intermediates - Structure, Reactivity and Application in Modern Chemistry

Faculty of Science
Spring 2025
Extent and Intensity
1/0/0. 1 credit(s) (plus extra credits for completion). Type of Completion: z (credit).
Teacher(s)
Dr. Ullrich Jahn (lecturer), Mgr. Jakub Švenda, PhD. (deputy)
Mgr. Jakub Švenda, PhD. (lecturer)
Guaranteed by
Mgr. Jakub Švenda, PhD.
Department of Chemistry – Chemistry Section – Faculty of Science
Supplier department: Department of Chemistry – Chemistry Section – Faculty of Science
Course Enrolment Limitations
The course is offered to students of any study field.
Course objectives
The course aims to provide the audience (PhD and master students) an advanced understanding of open shell intermediates (radicals, triplet carbenes or nitrenes). Their physical organic chemistry provides the basics for applying them in organic and technical chemistry. The general reactivity patterns of radicals, carbenes and nitrenes will be outlined and illustrated by selected modern lines of research and applications. As a result, the audience will be able to predictively apply the principles to their own research problems.
Syllabus
  • 1) Radicals, carbenes and nitrenes: Generation, electronic structure, thermodynamics, kinetics, general reactivity patterns
  • 2) Radical functionalization reactions, polar effects
  • 3) Radical addition reactions
  • 4) Radical cyclization reactions
  • 5) Radical cascade reactions and applications in total synthesis
  • 6) Radical-radical reactions – the persistent radical effect
  • 7) Redox reactions of radicals
  • 8) Emerging technologies based on radicals
  • 9) Reactivity of triplet carbenes and nitrenes
Language of instruction
English
Further Comments
The course is taught only once.
The course is taught: in blocks.
  • Permalink: https://is.muni.cz/course/sci/spring2025/IC167