BVPF0422p Pathological Physiology II - lecture

Faculty of Medicine
spring 2021
Extent and Intensity
2/0/0. 3 credit(s). Type of Completion: zk (examination).
Taught online.
prof. MUDr. Kateřina Kaňková, Ph.D. (lecturer)
prof. RNDr. Monika Pávková Goldbergová, Ph.D. (lecturer)
prof. MUDr. Anna Vašků, CSc. (lecturer)
prof. MUDr. Julie Dobrovolná, Ph.D. (lecturer)
MUDr. Michal Jurajda, Ph.D. (lecturer)
doc. RNDr. Michal Masařík, Ph.D. (lecturer)
Mgr. Lukáš Pácal, Ph.D. (lecturer)
Mgr. Lukáš Pácal, Ph.D. (seminar tutor)
Věra Ježková (assistant)
MVDr. Halina Matějová (assistant)
Guaranteed by
prof. MUDr. Kateřina Kaňková, Ph.D.
Department of Pathophysiology - Theoretical Departments - Faculty of Medicine
Contact Person: MVDr. Halina Matějová
Supplier department: Department of Pathophysiology - Theoretical Departments - Faculty of Medicine
Mon 1. 3. 13:00–14:40 A21/112, Mon 8. 3. 13:00–14:40 A21/112, Mon 15. 3. 13:00–14:40 A21/112, Mon 22. 3. 13:00–14:40 A21/112, Mon 29. 3. 13:00–14:40 A21/112, Mon 12. 4. 13:00–14:40 A21/112, Mon 19. 4. 13:00–14:40 A21/112, Mon 26. 4. 13:00–14:40 A21/112, Mon 3. 5. 13:00–14:40 A21/112, Mon 10. 5. 13:00–14:40 A21/112, Mon 17. 5. 13:00–14:40 A21/112, Mon 24. 5. 13:00–14:40 A21/112, Mon 31. 5. 13:00–14:40 A21/112, Mon 7. 6. 13:00–14:40 A21/112
Prerequisites (in Czech)
BVPF0321p Pathophysiology I - lecture
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
The main objectives are to understand : 1) the basics of ethiopathogenesis of common diseases, 2) principles of genetic determination of diseases and 3) the role of interindividual variability. The student will learn the basics of the following chapters: Pathophysiology of digestive system / Intermediary metabolism / Disorders of metabolism of main macronutrients (saccharides, lipids, proteins) and micronutrients / Disorders of nutrition (hypo-/malnutrition, malabsorption, catabolic states, metabolic syndrome and obesity) / Pathophysiology of heart and vessels & blood / Pathophysiology of respiratory system / Pathophysiology of renal system / Pathophysiology of nervous, musculosceletal and reproductive systems
Learning outcomes
Student will be able, after completing the course (with account of the width of the subject):
- to characterize the state of health and illness in terms of different concepts
- to distinguish the genetic determinants of disease, the influence of external factors on the occurrence of diseases, the difference between monogenic and multigenic/complex disease
- to orientate in terms: cell, cell cycle
- to characterize the term homeostasis
- to discuss external and internal factors of the disease
- to characterize basic concepts of tissue involvement and wound healing
- to explain the difference between local and systemic inflammation
- to explain the chronobiology function in medicine
- to discuss the etiopathogenesis of the most important disorders of ion equilibrium and regulation of volume and tonicity
- to define basic concepts of acid-base balance
- to evaluate the importance of abnormalities of the most important micronutrients, disorders in vitamin levels and trace elements
- to define the disorders in metabolism of carbohydrates, lipids, proteins and amino acids
- to characterize energy balance disorders.
  • Chronologically (week of the term):
  • 1 Pathophysiology of digestive system I – oral cavity, oesophagus, stomach, liver, billiary system
  • 2 Pathophysiology of digestive system II – pancreas, small and large intestines, malabsorption syndromes
  • 3 Pathophysiology of blood and bone marrow
  • 4 Pathophysiology of blood coagulation
  • 5 Disorders of nutrition I – starvation, malnutrition, malabsorption syndrome, catabolic states, mental anorexia and bulimia, tumor anorexia/cachexia
  • 6 Disorders of nutrition II – obesity and metabolic syndrome
  • 7 Easter (bank holiday)
  • 8 Pathophysiology of vessels I – atherosclerosis - ischemic heart disease – peripheral vessel diseases - shock
  • 9 Pathophysiology of vessels II – hypertension – venous insufficiency
  • 10 Pathophysiology of the heart - congenital and acquired heart disorders - heart failure
  • 11 Pathophysiology of respiratory system
  • 12 Pathophysiology of renal system
  • 13 Pathophysiology of musculosceletal systems
  • 14 Pathophysiology of nervous system I
  • 15 Pathophysiology of nervous system II
    required literature
  • KAŇKOVÁ, Kateřina, Dobroslav HÁJEK, Marcel HORKÝ, Lydie IZAKOVIČOVÁ HOLLÁ, Michal JURAJDA, Vladimír KOTALA, Jiří VÁCHA, Anna VAŠKŮ and Vladimír ZNOJIL. Patologická fyziologie pro bakalářské studijní programy (Pathophysiology for paramedical study programms). 1st ed. Brno: Masarykova univerzita v Brně, 2003. 161 pp. 1. vydání. ISBN 80-210-3112-3. info
  • KAŇKOVÁ, Kateřina. Vybrané kapitoly z patologické fyziologie: Poruchy metabolizmu a výživy. 1. vydání. Brno: Masarykova univerzita v Brně, 2005. 59 pp. ISBN 80-210-3670-2. info
Teaching methods
Assessment methods
oral exam
Language of instruction
Follow-Up Courses
Further comments (probably available only in Czech)
Study Materials
The course is taught annually.
Information on the extent and intensity of the course: 30.
Listed among pre-requisites of other courses
The course is also listed under the following terms Spring 2003, Spring 2004, Spring 2005, Spring 2006, Spring 2007, Spring 2008, Autumn 2008, Spring 2009, Spring 2010, Spring 2011, Spring 2012, Spring 2013, Spring 2014, Spring 2015, Spring 2016, Spring 2017, Spring 2018, spring 2019, spring 2020.
  • Enrolment Statistics (recent)
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