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LF:MIKAM021s Data Manag. and Anal. - pract. - Course Information

## MIKAM021s Data Management and Analysis for Medical branches - practice

**Faculty of Medicine**

spring 2021

**Extent and Intensity**- 0/0.3/0. 1 credit(s). Type of Completion: z (credit).
**Teacher(s)**- RNDr. Jiří Jarkovský, Ph.D. (seminar tutor)

RNDr. Denisa Krejčí (seminar tutor)

Mgr. et Mgr. Jiří Kalina, Ph.D. (seminar tutor)

RNDr. Danka Haruštiaková, Ph.D. (seminar tutor)

Silvie Doubravská (assistant) **Guaranteed by**- prof. RNDr. Ladislav Dušek, Ph.D.

Institute of Biostatistics and Analyses - Other Departments for Educational and Scientific Research Activities - Faculty of Medicine

Contact Person: Silvie Doubravská

Supplier department: Institute of Biostatistics and Analyses - Other Departments for Educational and Scientific Research Activities - Faculty of Medicine **Prerequisites**-
**MIKVO011s**Nursing research - practice

Basic experience with computer. **Course Enrolment Limitations**- The course is only offered to the students of the study fields the course is directly associated with.

**fields of study / plans the course is directly associated with**- Intensive Care (programme LF, N-IP)
- Intensive Care (programme LF, N-SZ)

**Course objectives**- The course introduces practical data analysis to students of clinical study specialisations. The course accompanies lectures of MIKAM021p Data analysis and data management and shows the computation of presented methods on PC using statistical software. Students will be trained in all aspects of data processing and its statistical analysis (descriptive statistics, one sample and two sample tests, categorical data analysis, ANOVA, correlation analysis, data visualisation).
**Learning outcomes**- Students will be able after the course to use the folowing data analysis methods:

- Descriptive statistics, data visualisation.

- Distribution of continuous variables.

- One sample tests - parametrical and nonparametrical.

- Two sample tests - parametrical and nonparametrical.

- Analysis of variance (ANOVA), Kruskal-Wallis test.

- Analysis of contingency table.

- Corelation, linear regression. **Syllabus**- 1. Data processing – principles of correct data manipulation. MS Office Excel – appropriate tool for storing, organizing, and manipulating data.
- 2. Introduction to statistics. Data types in medicine and biology; nominal, ordinal, continuous variable. Visualization of quantitative and qualitative (categorical) variables.
- 3. Descriptive statistics. Mean, median, quantiles, variance. Frequency table.
- 4. Distribution of continuous variables. Normal distribution, log-normal distribution.
- 5. Principles of hypotheses testing. Definition of null and alternative hypothesis. Significance level. Type I and type II error.
- 6. Graphical examining of normal distribution (histogram, normal-probability plot). Shapiro-Wilk test – a test of normality.
- 7. Parametrical tests: t-tests. One-sample t-test, two-sample t-test, t-test for dependent samples.
- 8. Analysis of variance ANOVA.
- 9. Nonparametrical tests: one-sample Wilcoxon test, Mann-Whitney U test, Wilcoxon test for dependent samples, Kruskal-Wallis test.
- 10. Definition of contingency table and its analysis: Pearson chi-square test, Fisher exact test, McNemar test.
- 11. Correlation. Pearson correlation coefficient, Spearman correlation coefficient.
- 12. Introduction to regression analysis. Linear regression.

**Literature**- ZAR, Jerrold H.
*Biostatistical analysis*. 5th ed. Upper Saddle River, N.J.: Prentice Hall, 2010. xiii, 944. ISBN 9780131008465. info - POCOCK, Stuart J.
*Clinical trials : a practical approach*. Chichester: John Wiley & Sons, 1999. xii, 266. ISBN 0471901555. info - MCFADDEN, Eleanor.
*Management of data in clinical trials*. 1st ed. New York: John Wiley & Sons, 1998. xi, 210. ISBN 047130316X. info - HAVRÁNEK, Tomáš.
*Statistika pro biologické a lékařské vědy*. 1. vyd. Praha: Academia, 1993. 476 s. ISBN 8020000801. info - ALTMAN, Douglas G.
*Practical statistics for medical research*. 1st ed. Boca Raton: Chapmann & Hall/CRC, 1991. xii, 611. ISBN 0412276305. info

*recommended literature*- ZAR, Jerrold H.
**Teaching methods**- Theoretical lectures supplemented by commented examples; students are encouraged to ask quaetions about discussed topics.
**Assessment methods**- Credit is given for attendance.
**Language of instruction**- Czech
**Further comments (probably available only in Czech)**- Information on the extent and intensity of the course: 5.

- Enrolment Statistics (spring 2021, recent)
- Permalink: https://is.muni.cz/course/med/spring2021/MIKAM021s