Course Information

aVLBI0222c Medical Biology II - practice

Extent and Intensity

0/3/0. 3 credit(s). Type of Completion: z (credit).
Taught in person.

Teacher(s)

prof. RNDr. Ondřej Slabý, Ph.D. (lecturer)
Mgr. et Mgr. Marie Boudná (seminar tutor)
Mgr. Kateřina Cetkovská, Ph.D. (seminar tutor)
Ing. Lívia Eiselleová, Ph.D. (seminar tutor)
Felicity Anne Feiser (seminar tutor)
Mgr. Kateřina Francová, Ph.D. (seminar tutor)
Monica Medappa (seminar tutor)
Roberto Pivato (seminar tutor)
Sara Poovakulathu Abraham, MSc (seminar tutor)
Mgr. Petra Pospíšilová, Ph.D. (seminar tutor)
Ing. Mgr. Michaela Ručková (seminar tutor)
Mgr. Marek Večeřa (seminar tutor)
Mgr. Simona Vochyánová (seminar tutor)
Jana Růžičková (assistant)

Guaranteed by

prof. RNDr. Ondřej Slabý, Ph.D.
Department of Biology – Theoretical Departments – Faculty of Medicine
Contact Person: Ing. Lívia Eiselleová, Ph.D.
Supplier department: Department of Biology – Theoretical Departments – Faculty of Medicine

Timetable of Seminar Groups

aVLBI0222c/28: Mon 14. 2. to Tue 10. 5. Tue 7:30–8:00 B07/214, Tue 8:00–9:30 B07/217, Tue 8:00–9:30 B07/214, Tue 9:30–10:00 B07/214
aVLBI0222c/29: Mon 14. 2. to Mon 9. 5. Mon 14:00–14:30 B07/214, Mon 14:30–16:00 B07/214, Mon 14:30–16:00 B07/217, Mon 16:00–16:30 B07/214
aVLBI0222c/30: Mon 14. 2. to Mon 9. 5. Mon 8:00–8:30 B07/214, Mon 8:30–10:00 B07/214, Mon 8:30–10:00 B07/217, Mon 10:00–10:30 B07/214
aVLBI0222c/31: Mon 14. 2. to Thu 12. 5. Thu 15:00–15:30 B07/214, Thu 15:30–17:00 B07/217, Thu 15:30–17:00 B07/214, Thu 17:00–17:30 B07/214
aVLBI0222c/32: Mon 14. 2. to Wed 11. 5. Wed 11:30–12:00 B07/214, Wed 12:00–13:30 B07/214, Wed 12:00–13:30 B07/217, Wed 13:30–14:00 B07/214
aVLBI0222c/33: Mon 14. 2. to Thu 12. 5. Thu 12:00–12:30 B07/214, Thu 12:30–14:00 B07/214, Thu 12:30–14:00 B07/217, Thu 14:00–14:30 B07/214
aVLBI0222c/34: Mon 14. 2. to Wed 11. 5. Wed 8:00–8:30 B07/214, Wed 8:30–10:00 B07/217, Wed 8:30–10:00 B07/214, Wed 10:00–10:30 B07/214
aVLBI0222c/35: Mon 14. 2. to Tue 10. 5. Tue 10:30–11:00 B07/214, Tue 11:00–12:30 B07/217, Tue 11:00–12:30 B07/214, Tue 12:30–13:00 B07/214
aVLBI0222c/36: Mon 14. 2. to Tue 10. 5. Tue 15:30–16:00 B07/214, Tue 16:00–17:30 B07/217, Tue 16:00–17:30 B07/214, Tue 17:30–18:00 B07/214
aVLBI0222c/37: Mon 14. 2. to Fri 13. 5. Fri 8:30–9:00 B07/214, Fri 9:00–10:30 B07/214, Fri 9:00–10:30 B07/217, Fri 10:30–11:00 B07/214
aVLBI0222c/38: Mon 14. 2. to Fri 13. 5. Fri 11:30–12:00 B07/214, Fri 12:00–13:30 B07/217, Fri 12:00–13:30 B07/214, Fri 13:30–14:00 B07/214
aVLBI0222c/39: Mon 14. 2. to Thu 12. 5. Thu 9:00–9:30 B07/214, Thu 9:30–11:00 B07/217, Thu 9:30–11:00 B07/214, Thu 11:00–11:30 B07/214

Prerequisites (in Czech)

aVLBI0121c Biology I - pract.

Course Enrolment Limitations

The course is only offered to the students of the study fields the course is directly associated with.

fields of study / plans the course is directly associated with

there are 6 fields of study the course is directly associated with, display

Course objectives

The main objectives of the course are:
- learning the methods of risk evaluation for hereditary diseases of various molecular background in patients based on family anamneses
- understanding the basic principles of gene engineering
- understanding and practicing selected molecular methods used for examination of some cancers or hereditary and infectious diseases with regard to the selection of appropriate therapy

Learning outcomes

After completing the course, the student will be able to:
- evaluate the risk of hereditary diseases of various molecular background in patients based on assigned family anamneses of the diseases
- describes the basic principles of genetic prognosis and genetic counseling
- suggest and perform basic molecular-genetic diagnostic examinations of some hereditary, tumour and infectious diseases (PCR, restriction digest, gel electrophoresis), and to interpret the obtained results
- explain selected basic techniques of gene engineering and their application in medicine, and, with knowledge of the used method, to select the clones of cells with an inserted gene

Syllabus

• Week 1: Genetic disorders - autosomal inheritance
• Week 2: Genetic disorders - gonosomal inheritance
• Week 3: Extensions to basic genetics
• Week 4: Genetic prognosis and genetic counselling
• Week 5: Human population genetics
• Week 6: Control test 3 (knowledge from week 1 to week 5 of the spring semester - lectures, practices)
• Week 7: Molecular diagnostics of human pathogenic bacteria (1st half of the group)
• Week 8: Molecular diagnostics of human pathogenic bacteria (2nd half of the group)
• Week 9: Gene engineering – production of human proteins in bacterial cells (1st half of the group)
• Week 10: Gene engineering – production of human proteins in bacterial cells (2nd half of the group)
• Week 11: Molecular diagnostics of cancer (1st half of the group)
• Week 12: Molecular diagnostics of cancer (2nd half of the group)
• Week 13: Control test 4 (knowledge from week 7 to week 12 of the spring semester - lectures, practices)
• Week 14: no practices, Re-sit test
• Week 15: no practices, credit awarding

Literature

required literature
• Protocols for practices are provided in electronic form in the Information System of the Masaryk University in the Study Materials of the course aVLBI0222c

Teaching methods

laboratory practice, class discussion

Assessment methods

Practical classes are mandatory.
Requirements for course completion: full attendance in the practices (1 absence, excused or unexcused, is allowed); all protocols completed (also for missed lessons) and checked and signed by appropriate teachers; successfully passed 2 written control tests during the semester (knowledge from lectures and practices, 20 questions in each test, 1 answer correct to be chosen from 4 possibilities, student needs to reach at least 24 points out of 40 from both of the tests). In case you do not pass control tests (you have less than 24 points), you write a re-sit of control test (knowledge from lectures and practices of entire semester, 20 questions, 1 answer correct to be chosen from 4 possibilities, student needs to reach at least 12 points). If you do not pass the re-sit of control test, you have to write the final test (Credit test) based on knowledge of the entire semester lectures and practices. Credit test comprises 20 questions: 10 test questions (multiple answers can be correct, negative marking is obtained for incorrect answers) + 10 given terms for a written explanation. At least 10 points out of 20 are needed to pass.
In case of a student’s late arrival to the practice or poor activity at the practice, the student is required to write an essay in the length of 2 pages on a given topic. Same for the case of two absences in practices (excused or unexcused). Find the instructions for essay writing in the Instructions for the course in Interactive syllabus in the IS. Bring the essay printed to the teacher who specified the topic (after making an appointment in consulting hours), and be ready to answer the teacher's questions regarding the topic.
In case of 3 absences (excused or unexcused), (or more than 3 absences all excused by the Office for Studies within 5 days from the beginning of the absence and introduced to the Information System), it is addressed individually and course-unit credit is awarded only after the proof of the student's knowledge of the entire semester topics (Credit test, see above).
In the case of 4 or more unexcused absences, the course-unit credit is not awarded.

Language of instruction

English

Follow-Up Courses

• aVLBC0321c Biochemistry I - practice
• aVLBC0321p Biochemistry I - lecture
• aVLBC0321s Biochemistry I - seminar
• aVLHE0322c Histology and Embryology II - practice
• aVLHE0322p Histology and Embryology II - lecture

Further comments (probably available only in Czech)

The course is taught annually.
Information on the extent and intensity of the course: 45.

Teacher's information

https://is.muni.cz/auth/el/med/jaro2022/aVLBI0222c/index.qwarp
Interactive syllabus of the course:
https://is.muni.cz/auth/el/med/jaro2022/aVLBI0222c/index.qwarp

What to bring to each practice: printed protocol for the respective practice, your own writing materials. Download the protocol for each practice from the Study materials or Interactive syllabus in the IS, and study it in advance. Lab shoes required, lab coats and disposable gloves are not required, but for the tasks with staining lab coats are recommended.

Substitution of practices: In exceptional cases (illness, appointment at the doctor’s or foreign policy, 1 or 2 times per semester as maximum) students can arrange a substitution with another group. To arrange a substitution, write an e-mail to the contact person of the course at least 24 hours before your planned substitution and specify the group (date and time) you would like to attend instead (see Interactive syllabus - Instructions for the course - Timetable). Substitution is only possible on the same teaching week. When the capacity of the group you intended to substitute with is fully used, the substitution does not need to be approved. Repeated substitution with other groups is not allowed.

Complete Biology instructions to be found at the following link: https://is.muni.cz/auth/el/med/jaro2022/aVLBI0222c/op/Biology_practices_instructions_2021_2022.pdf?predmet=1414977

aVLBI0222c Medical Biology II - practice

Extent and Intensity

0/3/0. 3 credit(s). Type of Completion: z (credit).
Taught in person.

Teacher(s)

prof. RNDr. Ondřej Slabý, Ph.D. (lecturer)
Mgr. Kateřina Cetkovská, Ph.D. (seminar tutor)
Ing. Lívia Eiselleová, Ph.D. (seminar tutor)
Felicity Anne Feiser (seminar tutor)
Mgr. Kateřina Francová, Ph.D. (seminar tutor)
Sebastiano Giallongo, Ph.D. (seminar tutor)
Monica Medappa (seminar tutor)
Master Alexandru Nită (seminar tutor)
Mgr. Markéta Nováková, Ph.D. (seminar tutor)
Daniel Pereira de Sousa, MSc (seminar tutor)
Sara Poovakulathu Abraham, MSc (seminar tutor)
Mgr. Petra Pospíšilová, Ph.D. (seminar tutor)
prof. MUDr. Iva Slaninová, Ph.D. (seminar tutor)
Mgr. Barbora Valčíková (seminar tutor)
Jana Růžičková (assistant)

Guaranteed by

prof. RNDr. Ondřej Slabý, Ph.D.
Department of Biology – Theoretical Departments – Faculty of Medicine
Contact Person: Ing. Lívia Eiselleová, Ph.D.
Supplier department: Department of Biology – Theoretical Departments – Faculty of Medicine

Timetable of Seminar Groups

aVLBI0222c/28: Mon 1. 3. to Thu 27. 5. Thu 12:00–12:30 B07/214, Thu 12:30–14:00 B07/214, Thu 12:30–14:00 B07/217, Thu 14:00–14:30 B07/214
aVLBI0222c/29: Mon 1. 3. to Tue 25. 5. Tue 10:00–10:30 B07/214, Tue 10:30–12:00 B07/214, Tue 10:30–12:00 B07/217, Tue 12:00–12:30 B07/214
aVLBI0222c/30: Mon 1. 3. to Wed 26. 5. Wed 11:00–11:30 B07/214, Wed 11:30–13:00 B07/214, Wed 11:30–13:00 B07/217, Wed 13:00–13:30 B07/214
aVLBI0222c/31: Mon 1. 3. to Tue 25. 5. Tue 7:00–7:30 B07/214, Tue 7:30–9:00 B07/217, Tue 7:30–9:00 B07/214, Tue 9:00–9:30 B07/214
aVLBI0222c/32: Mon 1. 3. to Mon 24. 5. Mon 8:00–8:30 B07/214, Mon 8:30–10:00 B07/217, Mon 8:30–10:00 B07/214, Mon 10:00–10:30 B07/214
aVLBI0222c/33: Mon 1. 3. to Tue 25. 5. Tue 13:00–13:30 B07/214, Tue 13:30–15:00 B07/217, Tue 13:30–15:00 B07/214, Tue 15:00–15:30 B07/214
aVLBI0222c/34: Mon 1. 3. to Wed 26. 5. Wed 15:30–16:00 B07/214, Wed 16:00–17:30 B07/217, Wed 16:00–17:30 B07/214, Wed 17:30–18:00 B07/214
aVLBI0222c/35: Mon 1. 3. to Thu 27. 5. Thu 15:00–15:30 B07/214, Thu 15:30–17:00 B07/217, Thu 15:30–17:00 B07/214, Thu 17:00–17:30 B07/214
aVLBI0222c/36: Mon 1. 3. to Fri 28. 5. Fri 8:30–9:00 B07/214, Fri 9:00–10:30 B07/217, Fri 9:00–10:30 B07/214, Fri 10:30–11:00 B07/214
aVLBI0222c/37: Mon 1. 3. to Wed 26. 5. Wed 8:00–8:30 B07/214, Wed 8:30–10:00 B07/217, Wed 8:30–10:00 B07/214, Wed 10:00–10:30 B07/214
aVLBI0222c/38: Mon 1. 3. to Mon 24. 5. Mon 14:00–14:30 B07/214, Mon 14:30–16:00 B07/217, Mon 14:30–16:00 B07/214, Mon 16:00–16:30 B07/214
aVLBI0222c/39: Mon 1. 3. to Fri 28. 5. Fri 11:30–12:00 B07/214, Fri 12:00–13:30 B07/217, Fri 12:00–13:30 B07/214, Fri 13:30–14:00 B07/214

Prerequisites (in Czech)

aVLBI0121c Biology I - pract.

Course Enrolment Limitations

The course is only offered to the students of the study fields the course is directly associated with.

fields of study / plans the course is directly associated with

there are 6 fields of study the course is directly associated with, display

Course objectives

The main objectives of the course are:
- learning the methods of risk evaluation for hereditary diseases of various molecular background in patients based on family anamneses
- understanding the basic principles of gene engineering
- understanding and practicing selected molecular methods used for examination of some cancers or hereditary and infectious diseases with regard to the selection of appropriate therapy

Learning outcomes

After completing the course, the student will be able to:
- evaluate the risk of hereditary diseases of various molecular background in patients based on assigned family anamneses of the diseases
- describes the basic principles of genetic prognosis and genetic counseling
- suggest and perform basic molecular-genetic diagnostic examinations of some hereditary, tumour and infectious diseases (PCR, restriction digest, gel electrophoresis), and to interpret the obtained results
- explain selected basic techniques of gene engineering and their application in medicine, and, with knowledge of the used method, to select the clones of cells with an inserted gene
- explain the basic laboratory tests used in genetic toxicology and the overall use of genetic toxicology, and to interpret the results obtained by selected methods

Syllabus

• Week 1: Genetic disorders - autosomal inheritance
• Week 2: Genetic disorders - gonosomal inheritance
• Week 3: Extensions to basic genetics
• Week 4: Genetic prognosis and genetic counselling
• Week 5: Human population genetics
• Week 6: Control test 3 (knowledge from week 1 to week 5 of the spring semester - practices only)
• Week 7: Molecular diagnostics of cancer
• Week 8: Molecular diagnostics of cancer
• Week 9: Gene engineering – production of human proteins in bacterial cells
• Week 10: Gene engineering – production of human proteins in bacterial cells
• Week 11: Molecular diagnostics of human pathogenic bacteria
• Week 12: Molecular diagnostics of human pathogenic bacteria
• Week 13: Control test 4 (knowledge from week 7 to week 12 of the spring semester - practices only)
• Week 14: dissection week - no practices Re-sit test
• Week 15: dissection week - no practices, credit awarding

Literature

required literature
• Protocols for practices are provided in electronic form in the Information System of the Masaryk University in the Study Materials of the course aVLBI0222c

Teaching methods

laboratory practice, class discussion

Assessment methods

Practical classes are mandatory.
Requirements for course completion: full attendance in the practices (1 absence, excused or unexcused, is allowed); all protocols completed (also for missed lessons) and checked and signed by appropriate teachers; successfully passed 2 written control tests during the semester (20 questions each, 4 possibilities, 1 answer correct, student need to reach at least 24 points out of 40 from both of the tests). In case you do not pass control tests and their re-sit, you have to pass the final test (Credit test) based on knowledge of the entire semester lectures and practices. The test comprises of 20 questions: 10 test questions (multiple answers can be correct, negative marking is obtained for incorrect answers) + 10 given terms for a written explanation. At least 10 points out of 20 are needed to pass.
In case of a student’s late arrival to the practice or poor activity at the practice, the student is required to write an essay in the length of 2 pages on a given topic. Same for the case of 2nd and any additional absence in practices (excused or unexcused). Find the instructions for essay writing in the Course-related instructions in the IS. Bring the essay printed to the teacher who specified the topic, and be ready to answer the teacher's questions regarding the topic.
In case of 3 absences, (or more than 3 absences all excused by the Office for Studies within 5 days from the beginning of the absence and introduced to the Information System), it is addressed individually and course-unit credit is awarded only after the proof of the student's knowledge of the entire semester topics (Credit test, see above).
In the case of 4 or more unexcused absences, the course-unit credit is not awarded.

Language of instruction

English

Follow-Up Courses

• aVLBC0321c Biochemistry I - practice
• aVLBC0321p Biochemistry I - lecture
• aVLBC0321s Biochemistry I - seminar
• aVLHE0322c Histology and Embryology II - practice
• aVLHE0322p Histology and Embryology II - lecture

Further comments (probably available only in Czech)

Study Materials
The course is taught annually.
Information on the extent and intensity of the course: 45.

Teacher's information

https://is.muni.cz/auth/el/1411/jaro2018/aVLBI0222c/index.qwarp
What to bring to each practice: printed protocol for the respective practice, your own writing materials. Download the protocol for each practice from the Study materials in the IS, and study it in advance. Lab shoes required, lab coats and disposable gloves are not required, but for the tasks with staining lab coats are recommended.

Substitution of practices: In exceptional cases (illness, appointment at the doctor’s or foreign policy, 1 or 2 times per semester as maximum) students can arrange a substitution with another group. To arrange a substitution, write an e-mail to the contact person of the course at least 24 hours before your planned substitution and specify the group (date and time) you would like to attend instead. Substitution is only possible on the same teaching week. When the capacity of the group you intended to substitute with is fully used, the substitution does not need to be approved. Repeated substitution with other groups is not allowed.

Complete Biology instructions to be found at the following link: https://is.muni.cz/auth/el/1411/jaro2021/aVLBI0222c/op/Biology_practices_instructions.pdf

aVLBI0222c Biology II - practice

Extent and Intensity

0/3/0. 3 credit(s). Type of Completion: z (credit).

Teacher(s)

Ing. Lívia Eiselleová, Ph.D. (lecturer)
prof. RNDr. Ondřej Slabý, Ph.D. (lecturer)
Mgr. Kateřina Cetkovská, Ph.D. (seminar tutor)
Mgr. Kateřina Francová, Ph.D. (seminar tutor)
Sebastiano Giallongo, Ph.D. (seminar tutor)
Master Alexandru Nită (seminar tutor)
Mgr. Markéta Nováková, Ph.D. (seminar tutor)
Sara Poovakulathu Abraham, MSc (seminar tutor)
Mgr. Petra Pospíšilová, Ph.D. (seminar tutor)
Nicola Silva, PhD. (seminar tutor)
prof. MUDr. Iva Slaninová, Ph.D. (seminar tutor)
Jana Růžičková (assistant)

Guaranteed by

prof. MUDr. David Šmajs, Ph.D.
Department of Biology – Theoretical Departments – Faculty of Medicine
Contact Person: Ing. Lívia Eiselleová, Ph.D.
Supplier department: Department of Biology – Theoretical Departments – Faculty of Medicine

Timetable of Seminar Groups

aVLBI0222c/30: Mon 17. 2. to Fri 15. 5. Fri 10:30–11:00 B07/214, Fri 11:00–12:30 B07/214, Fri 11:00–12:30 B07/217, Fri 12:30–13:00 B07/214
aVLBI0222c/31: Mon 17. 2. to Wed 13. 5. Wed 8:00–8:30 B07/214, Wed 8:30–10:00 B07/217, Wed 8:30–10:00 B07/214, Wed 10:00–10:30 B07/214
aVLBI0222c/32: Mon 17. 2. to Tue 12. 5. Tue 13:00–13:30 B07/214, Tue 13:30–15:00 B07/214, Tue 13:30–15:00 B07/217, Tue 15:00–15:30 B07/214
aVLBI0222c/33: Mon 17. 2. to Thu 14. 5. Thu 9:30–10:00 B07/214, Thu 10:00–11:30 B07/214, Thu 10:00–11:30 B07/217, Thu 11:30–12:00 B07/214
aVLBI0222c/34: Mon 17. 2. to Mon 11. 5. Mon 8:00–8:30 B07/214, Mon 8:30–10:00 B07/217, Mon 8:30–10:00 B07/214, Mon 10:00–10:30 B07/214
aVLBI0222c/35: Mon 17. 2. to Tue 12. 5. Tue 10:00–10:30 B07/214, Tue 10:30–12:00 B07/214, Tue 10:30–12:00 B07/217, Tue 12:00–12:30 B07/214
aVLBI0222c/36: Mon 17. 2. to Fri 15. 5. Fri 12:00–12:30 B07/205a, Fri 12:30–14:00 B07/217, Fri 12:30–14:00 B07/205a, Fri 14:00–14:30 B07/205a
aVLBI0222c/37: Mon 17. 2. to Thu 14. 5. Thu 12:30–13:00 B07/214, Thu 13:00–14:30 B07/214, Thu 13:00–14:30 B07/217, Thu 14:30–15:00 B07/214
aVLBI0222c/38: Mon 17. 2. to Wed 13. 5. Wed 13:00–13:30 B07/214, Wed 13:30–15:00 B07/217, Wed 13:30–15:00 B07/214, Wed 15:00–15:30 B07/214
aVLBI0222c/39: Mon 17. 2. to Mon 11. 5. Mon 14:00–14:30 B07/214, Mon 14:30–16:00 B07/214, Mon 14:30–16:00 B07/217, Mon 16:00–16:30 B07/214

Prerequisites (in Czech)

aVLBI0121c Biology I - pract. && aVLBI0121s Biology I - seminar

Course Enrolment Limitations

The course is only offered to the students of the study fields the course is directly associated with.

fields of study / plans the course is directly associated with

• General Medicine (eng.) (programme LF, M-VL)
• General Medicine (programme LF, M-VL) (2)

Course objectives

The main objectives of the course are:
- learning the methods of risk evaluation for hereditary diseases of various molecular background in patients based on family anamneses
- understanding the basic principles of gene engineering
- understanding and practicing the selected molecular methods used for examination of some cancers or hereditary and infectious diseases with regard to selection of appropriate therapy

Learning outcomes

After completing the course, the student will be able to:
- evaluate the risk of hereditary diseases of various molecular background in patients based on assigned family anamneses of the diseases
- describes the basic principles of genetic prognosis and genetic counselling
- suggest and perform basic molecular-genetic diagnostic examinations of some hereditary, tumour and infectious diseases (PCR, restriction digest, gel electrophoresis), and to interpret the obtained results
- explain selected basic techniques of gene engineering and their application in medicine, and, with knowledge of the used method, to select the clones of cells with an inserted gene
- explain the basic laboratory tests used in genetic toxicology and the overall use of genetic toxicology, and to interpret the results obtained by selected methods

Syllabus

• Week 1: Genetic disorders - gonosomal inheritance
• Week 2: Extensions to basic genetics
• Week 3: Genetic prognosis and genetic counselling
• Week 4: Human population genetics
• Week 5: Control test 3 (knowledge from week 13 of the autumn semester to week 4 of the spring semester - lectures, seminar, practices)
• Week 6: Molecular diagnostics of cancer with respect to treatment options
• Week 7: Gene engineering – production of human proteins in bacterial cells
• Week 8: Molecular analysis of predispositions to cardiovascular disease in humans
• Week 9: Molecular diagnostics of human pathogenic bacteria
• Week 10: Restriction mapping of DNA
• Week 11: Genetic toxicology
• Week 12: substitution practices – substitutions for public holidays
• Week 13: Control test 4 (knowledge from week 5 to week 12 of the spring semester - lectures, practices)
• Week 14: dissection week – no practices
• Week 15: dissection week – no practices

Literature

required literature
• Protocols for practices are provided in electronic form in the Information System of the Masaryk University in the Study Materials of the course aVLBI0222c

Teaching methods

laboratory practice, class discussion

Assessment methods

Practical classes are mandatory.
Requirements for the course completion: full attendance in the practices (1 absence, excused or unexcused, is allowed); all protocols completed (also for missed lessons) and checked and signed by appropriate teachers; successfully passed 2 written control tests during the semester (20 questions each, 4 possibilities, 1 answer correct, student need to reach at least 12 points out of 20 in each test). In case you do not pass one of the control tests and its re-sit, you have to pass the final test (Credit test) based on knowledge of the entire semester lectures and practices. The test comprises of 20 questions: 10 test questions (multiple answers can be correct, negative marking is obtained for incorrect answers) + 10 given terms for a written explanation. At least 10 points out of 20 are needed to pass.
In case of student’s late arrival to the practice or poor activity at the practice, the student is required to write an essay in the length of 2 pages on a given topic. Same for the case of 2nd and any additional absence in practices (excused or unexcused). Find the instructions for essay writing in the Course-related instructions in the IS. Bring the essay printed to the teacher who specified the topic, and be ready to answer the teacher's questions regarding the topic.
In case of 3 absences, (or more than 3 absences all excused by the Office for Studies within 5 days from the beginning of the absence and introduced to the Information System), it is addressed individually and course-unit credit is awarded only after the proof of the student's knowledge of the entire semester topics (Credit test, see above).
In the case of 4 or more unexcused absences, the course-unit credit is not awarded.

Language of instruction

English

Follow-Up Courses

• aVLBC0321c Biochemistry I - practice
• aVLBC0321p Biochemistry I - lecture
• aVLBC0321s Biochemistry I - seminar
• aVLHE0322c Histology and Embryology II - practice
• aVLHE0322p Histology and Embryology II - lecture

Further comments (probably available only in Czech)

The course is taught annually.
Information on the extent and intensity of the course: 45.

Teacher's information

https://is.muni.cz/auth/el/1411/jaro2020/aVLBI0222c/index.qwarp
What to bring to each practice: printed protocol for the respective practice, your own writing materials. Download the protocol for each practice from the Study materials in the IS, and study it in advance. Lab shoes, lab coats and disposable gloves are not required, but for the tasks with staining lab coats are recommended.

Substitution of practices: In exceptional cases (illness, appointment at the doctor’s or foreign policy, 1 or 2 times per semester as maximum) student can arrange a substitution with another group. To arrange a substitution, write an e-mail to the contact person of the course at least 24 hours before your planned substitution and specify the group (date and time) you would like to attend instead. Substitution is only possible on the same teaching week. When the capacity of the group you intended to substitute with is fully used, the substitution does not need to be approved. Repeated substitution with other groups is not allowed.

Complete Biology instructions to be found at the following link: https://is.muni.cz/auth/el/1411/jaro2020/aVLBI0222c/op/Biology_practices_instructions.pdf

aVLBI0222c Biology II - practice

Extent and Intensity

0/3/0. 3 credit(s). Type of Completion: z (credit).

Teacher(s)

Ing. Lívia Eiselleová, Ph.D. (lecturer)
prof. RNDr. Ondřej Slabý, Ph.D. (lecturer)
Mgr. Bohumil Fafílek, Ph.D. (seminar tutor)
Mgr. Hana Hříbková, Ph.D. (seminar tutor)
Master Alexandru Nită (seminar tutor)
Mgr. Markéta Nováková, Ph.D. (seminar tutor)
Mgr. Veronika Palušová, Ph.D. (seminar tutor)
MUDr. Martin Pešl, Ph.D. (seminar tutor)
Mgr. Petra Pospíšilová, Ph.D. (seminar tutor)
Mgr. Vladimír Rotrekl, Ph.D. (seminar tutor)
prof. MUDr. Iva Slaninová, Ph.D. (seminar tutor)
Mgr. Barbora Valčíková (seminar tutor)
Gretsen Velezmoro Jauregui, M.Sc. (seminar tutor)
Mgr. Kateřina Vopěnková, Ph.D. (seminar tutor)
Jana Růžičková (assistant)

Guaranteed by

prof. Ing. Petr Dvořák, CSc.
Department of Biology – Theoretical Departments – Faculty of Medicine
Contact Person: Mgr. Kateřina Vopěnková, Ph.D.
Supplier department: Department of Biology – Theoretical Departments – Faculty of Medicine

Timetable of Seminar Groups

aVLBI0222c/28: Mon 18. 2. to Thu 16. 5. Thu 8:30–9:00 B07/214, Thu 9:00–10:30 B07/214, Thu 9:00–10:30 B07/217, Thu 10:30–11:00 B07/214
aVLBI0222c/29: Mon 18. 2. to Tue 14. 5. Tue 7:30–8:00 B07/214, Tue 8:00–9:30 B07/214, Tue 8:00–9:30 B07/217, Tue 9:30–10:00 B07/214
aVLBI0222c/30: Mon 18. 2. to Fri 17. 5. Fri 12:30–13:00 B07/214, Fri 13:00–14:30 B07/217, Fri 13:00–14:30 B07/214, Fri 14:30–15:00 B07/214
aVLBI0222c/31: Mon 18. 2. to Mon 13. 5. Mon 8:30–9:00 B07/214, Mon 9:00–10:30 B07/214, Mon 9:00–10:30 B07/217, Mon 10:30–11:00 B07/214
aVLBI0222c/32: Mon 18. 2. to Wed 15. 5. Wed 8:00–8:30 B07/214, Wed 8:30–10:00 B07/214, Wed 8:30–10:00 B07/217, Wed 10:00–10:30 B07/214
aVLBI0222c/33: Mon 18. 2. to Wed 15. 5. Wed 11:00–11:30 B07/214, Wed 11:30–13:00 B07/217, Wed 11:30–13:00 B07/214, Wed 13:00–13:30 B07/214
aVLBI0222c/34: Mon 18. 2. to Mon 13. 5. Mon 16:00–16:30 B07/214, Mon 16:30–18:00 B07/217, Mon 16:30–18:00 B07/214, Mon 18:00–18:30 B07/214
aVLBI0222c/35: Mon 18. 2. to Thu 16. 5. Thu 14:30–15:00 B07/214, Thu 15:00–16:30 B07/217, Thu 15:00–16:30 B07/214, Thu 16:30–17:00 B07/214
aVLBI0222c/36: Mon 18. 2. to Fri 17. 5. Fri 9:30–10:00 B07/214, Fri 10:00–11:30 B07/214, Fri 10:00–11:30 B07/217, Fri 11:30–12:00 B07/214
aVLBI0222c/37: Mon 18. 2. to Tue 14. 5. Tue 10:30–11:00 B07/214, Tue 11:00–12:30 B07/214, Tue 11:00–12:30 B07/217, Tue 12:30–13:00 B07/214
aVLBI0222c/38: Mon 18. 2. to Thu 16. 5. Thu 11:30–12:00 B07/214, Thu 12:00–13:30 B07/214, Thu 12:00–13:30 B07/217, Thu 13:30–14:00 B07/214
aVLBI0222c/39: Mon 18. 2. to Fri 17. 5. Fri 11:00–11:30 B07/205a, Fri 11:30–13:00 B07/217, Fri 11:30–13:00 B07/205a, Fri 13:00–13:30 B07/205a

Prerequisites (in Czech)

aVLBI0121c Biology I - pract. && aVLBI0121s Biology I - seminar

Course Enrolment Limitations

The course is only offered to the students of the study fields the course is directly associated with.

fields of study / plans the course is directly associated with

• General Medicine (eng.) (programme LF, M-VL)
• General Medicine (programme LF, M-VL) (2)

Course objectives

The main objectives of the course are:
- learning the methods of risk evaluation for hereditary diseases of various molecular background in patients based on family anamneses
- understanding the basic principles of gene engineering
- understanding and practicing the selected molecular methods used for examination of some cancers or hereditary and infectious diseases with regard to selection of appropriate therapy

Learning outcomes

After completing the course the student will be able to:
- evaluate the risk of hereditary diseases of various molecular background in patients based on assigned family anamneses of the diseases
- describes the basic principles of genetic prognosis and genetic counselling
- suggest and perform basic molecular-genetic diagnostic examinations of some hereditary, tumour and infectious diseases (PCR, restriction digest, gel electrophoresis), and to interpret the obtained results
- explain selected basic techniques of gene engineering and their application in medicine, and, with knowledge of the used method, to select the clones of cells with an inserted gene
- explain the basic laboratory tests used in genetic toxicology and the overall use of genetic toxicology, and to interpret the results obtained by selected methods

Syllabus

• Week 1: Genetic disorders - gonosomal inheritance
• Week 2: Deviations from Mendelian genetics
• Week 3: Genetic prognosis and genetic counselling
• Week 4: Human population genetics
• Week 5: Control test 3 (knowledge from week 13 of the autumn semester to week 4 of the spring semester - lectures, seminar, practices)
• Week 6: Molecular diagnostics of cancer with respect to treatment options
• Week 7: Gene engineering – production of human proteins in bacterial cells
• Week 8: Molecular analysis of disease predispositions in humans
• Week 9: Molecular diagnostics of human pathogenic bacteria
• Week 10: Restriction mapping of DNA
• Week 11: Genetic toxicology
• Week 12: substitution practices – substitutions for public holidays
• Week 13: Control test 4 (knowledge from week 5 to week 12 of the spring semester - lectures, practices)
• Week 14: dissection week – no practices
• Week 15: dissection week – no practices

Literature

required literature
• Protocols for practices are provided in electronic form in the Information System of the Masaryk University in the Study Materials of the course aVLBI0222c

Teaching methods

laboratory practice, class discussion

Assessment methods

Practical classes are mandatory.
Requirements for course completion: full attendance in the practices (1 absence, excused or unexcused, is allowed); all protocols completed (also for missed lessons) and checked and signed by appropriate teachers; successfully passed 2 written control tests during the semester (20 questions each, 4 possibilities, 1 answer correct, student need to reach at least 12 points out of 20 in each test). In case you do not pass one of the control tests and its re-sit, you have to pass the final test (so-called Credit test) based on knowledge of the entire semester lectures and practices. The test comprises of 20 questions: 10 test questions (multiple answers can be correct, negative marking is obtained for incorrect answers) + 10 given terms for written explanation. At least 10 points out of 20 are needed to pass.
In case of student’s late arrival to the practice or poor activity at the practice, the student is required to write an essay in the length of 2 pages on a given topic. Same for the case of 2nd and any additional absence in practices (excused or unexcused). Find the instructions for essay writing in the Course-related instructions in the IS, bring the essay printed to the teacher who specified the topic and be ready to answer the teacher's questions regarding the topic.
In case of 3 absences, (or more than 3 absences all excused by the Office for Studies within 5 days from the beginning of the absence and introduced to the Information System), it is addressed individually and course-unit credit is awarded only after the proof of the student's knowledge of the entire semester topics (Credit test, see above).
In case of 4 or more unexcused absences, course-unit credit is not awarded.

Language of instruction

English

Follow-Up Courses

• aVLBC0321c Biochemistry I - practice
• aVLBC0321p Biochemistry I - lecture
• aVLBC0321s Biochemistry I - seminar
• aVLHE0322c Histology and Embryology II - practice
• aVLHE0322p Histology and Embryology II - lecture

Further comments (probably available only in Czech)

The course is taught annually.
Information on the extent and intensity of the course: 45.

Teacher's information

https://is.muni.cz/auth/el/1411/jaro2018/aVLBI0222c/index.qwarp

aVLBI0222c Biology II - practice

Extent and Intensity

0/3/0. 2 credit(s). Type of Completion: z (credit).

Teacher(s)

Mgr. Kateřina Straková, Ph.D. (lecturer)
Ing. Lívia Eiselleová, Ph.D. (seminar tutor)
Mgr. Petr Fojtík, Ph.D. (seminar tutor)
Mgr. Pavla Havlíčková (seminar tutor)
Mgr. Matěj Hrala (seminar tutor)
Mgr. Hana Hříbková, Ph.D. (seminar tutor)
Mgr. Pavla Hujová, Ph.D. (seminar tutor)
Mgr. Šárka Jelínková, Ph.D. (seminar tutor)
Mgr. Aneta Kohutová, Ph.D. (seminar tutor)
Mgr. Tatiana Kováčová, Ph.D. (seminar tutor)
Mgr. Karolína Marková (seminar tutor)
Mgr. Markéta Nováková, Ph.D. (seminar tutor)
Mgr. Veronika Palušová, Ph.D. (seminar tutor)
MUDr. Martin Pešl, Ph.D. (seminar tutor)
Mgr. Petra Pospíšilová, Ph.D. (seminar tutor)
Mgr. Vladimír Rotrekl, Ph.D. (seminar tutor)
prof. MUDr. Iva Slaninová, Ph.D. (seminar tutor)
Mgr. Kateřina Straková, Ph.D. (seminar tutor)
Mgr. Barbora Valčíková (seminar tutor)
Gretsen Velezmoro Jauregui, M.Sc. (seminar tutor)
Mgr. Kateřina Vopěnková, Ph.D. (seminar tutor)
Jana Růžičková (assistant)

Guaranteed by

prof. Ing. Petr Dvořák, CSc.
Department of Biology – Theoretical Departments – Faculty of Medicine
Contact Person: Mgr. Kateřina Vopěnková, Ph.D.
Supplier department: Department of Biology – Theoretical Departments – Faculty of Medicine

Timetable of Seminar Groups

aVLBI0222c/30: Thu 14:00–16:30 B07/214
aVLBI0222c/31: Thu 11:10–13:40 B07/214
aVLBI0222c/32: Tue 14:30–17:00 B07/214
aVLBI0222c/33: Mon 7:30–10:00 B07/214
aVLBI0222c/34: Fri 11:10–13:40 B07/214
aVLBI0222c/35: Fri 8:30–11:00 B07/214
aVLBI0222c/36: Wed 10:10–12:40 B07/214
aVLBI0222c/37: Thu 8:30–11:00 B07/214
aVLBI0222c/38: Mon 14:00–16:30 B07/214
aVLBI0222c/39: Tue 9:00–11:30 B07/214

Prerequisites (in Czech)

aVLBI0121c Biology I - pract. && aVLBI0121s Biology I - seminar

Course Enrolment Limitations

The course is only offered to the students of the study fields the course is directly associated with.

fields of study / plans the course is directly associated with

• General Medicine (eng.) (programme LF, M-VL)
• General Medicine (programme LF, M-VL) (2)

Course objectives

The main objectives of the course are:
- learning the methods of risk evaluation for hereditary diseases of various molecular background in patients based on family anamneses
- understanding the basic principles of gene engineering
- understanding and practicing the selected molecular methods used for examination of some cancers or hereditary and infectious diseases with regard to selection of appropriate therapy

Learning outcomes

After completing the course the student will be able to:
- evaluate the risk of hereditary diseases of various molecular background in patients based on assigned family anamneses of the diseases
- describes the basic principles of genetic prognosis and genetic counselling
- suggest and perform basic molecular-genetic diagnostic examinations of some hereditary, tumour and infectious diseases (PCR, restriction digest, gel electrophoresis), and to interpret the obtained results
- explain selected basic techniques of gene engineering and their application in medicine, and, with knowledge of the used method, to select the clones of cells with an inserted gene
- explain the basic laboratory tests used in genetic toxicology and the overall use of genetic toxicology, and to interpret the results obtained by selected methods

Syllabus

• Week 1: Genetic disorders - gonosomal inheritance
• Week 2: Deviations from Mendelian genetics
• Week 3: Genetic prognosis and genetic counselling
• Week 4: Human population genetics
• Week 5: Control test 3 (knowledge from week 13 of the autumn semester to week 4 of the spring semester - lectures, seminar, practices)
• Week 6: Molecular diagnostics of cancer with respect to treatment options
• Week 7: Gene engineering – production of human proteins in bacterial cells
• Week 8: Molecular analysis of disease predispositions in humans
• Week 9: Molecular diagnostics of human pathogenic bacteria
• Week 10: Restriction mapping of DNA
• Week 11: Genetic toxicology
• Week 12: substitution practices – substitutions for public holidays
• Week 13: Control test 4 (knowledge from week 5 to week 12 of the spring semester - lectures, practices)
• Week 14: dissection week – no practices
• Week 15: dissection week – no practices

Literature

required literature
• Protocols for practices are provided in electronic form in the Information System of the Masaryk University in the Study Materials of the course aVLBI0222c

Teaching methods

laboratory practice, class discussion

Assessment methods

Practical classes are mandatory.
Requirements for course completion: full attendance in the practices (1 absence, excused or unexcused, is allowed); all protocols completed (also for missed lessons) and checked and signed by appropriate teachers; successfully passed 2 written control tests during the semester (20 questions each, 4 possibilities, 1 answer correct, student need to reach at least 12 points out of 20 in each test). In case you do not pass one of the control tests and its re-sit, you have to pass the final test (so-called Credit test) based on knowledge of the entire semester lectures and practices. The test comprises of 20 questions: 10 test questions (multiple answers can be correct, negative marking is obtained for incorrect answers) + 10 given terms for written explanation. At least 10 points out of 20 are needed to pass.
In case of student’s late arrival to the practice or poor activity at the practice, the student is required to write an essay in the length of 2 pages on a given topic. Same for the case of 2nd and any additional absence in practices (excused or unexcused). Find the instructions for essay writing in the Course-related instructions in the IS, bring the essay printed to the teacher who specified the topic and be ready to answer the teacher's questions regarding the topic.
In case of 3 absences, (or more than 3 absences all excused by the Office for Studies within 5 days from the beginning of the absence and introduced to the Information System), it is addressed individually and course-unit credit is awarded only after the proof of the student's knowledge of the entire semester topics (Credit test, see above).
In case of 4 or more unexcused absences, course-unit credit is not awarded.

Language of instruction

English

Follow-Up Courses

• aVLBC0321c Biochemistry I - practice
• aVLBC0321p Biochemistry I - lecture
• aVLBC0321s Biochemistry I - seminar
• aVLHE0322c Histology and Embryology II - practice
• aVLHE0322p Histology and Embryology II - lecture

Further comments (probably available only in Czech)

The course is taught annually.

Teacher's information

https://is.muni.cz/auth/el/1411/jaro2018/aVLBI0222c/index.qwarp

aVLBI0222c Biology II - practice

Extent and Intensity

0/3. 2 credit(s). Type of Completion: z (credit).

Teacher(s)

Ivana Aćimović, M.Sc., Ph.D. (seminar tutor)
Mgr. Kateřina Cetkovská, Ph.D. (seminar tutor)
Mgr. Petr Fojtík, Ph.D. (seminar tutor)
Mgr. Iva Gudernová (seminar tutor)
Mgr. Pavla Havlíčková (seminar tutor)
Mgr. Šárka Jelínková, Ph.D. (seminar tutor)
Mgr. Aneta Kohutová, Ph.D. (seminar tutor)
Mgr. Karolína Marková (seminar tutor)
Mgr. Markéta Nováková, Ph.D. (seminar tutor)
Mgr. Veronika Palušová, Ph.D. (seminar tutor)
Mgr. Lenka Paštěková, Ph.D. (seminar tutor)
MUDr. Martin Pešl, Ph.D. (seminar tutor)
Mgr. Vladimír Rotrekl, Ph.D. (seminar tutor)
prof. MUDr. Iva Slaninová, Ph.D. (seminar tutor)
Mgr. Kateřina Straková, Ph.D. (seminar tutor)
Shyam Sushama Jose, Ph.D. (seminar tutor)
Mgr. Barbora Štefanovie, Ph.D. (seminar tutor)
Mgr. Barbora Valčíková (seminar tutor)
Mgr. Tereza Váňová, Ph.D. (seminar tutor)
Mgr. Kateřina Vopěnková, Ph.D. (seminar tutor)
Jana Růžičková (assistant)
Mgr. Martina Vráblíková (assistant)

Guaranteed by

prof. Ing. Petr Dvořák, CSc.
Department of Biology – Theoretical Departments – Faculty of Medicine
Contact Person: Mgr. Kateřina Vopěnková, Ph.D.
Supplier department: Department of Biology – Theoretical Departments – Faculty of Medicine

Timetable of Seminar Groups

aVLBI0222c/30: Thu 14:00–16:30 B07/214
aVLBI0222c/31: Thu 11:10–13:40 B07/214
aVLBI0222c/32: Tue 14:30–17:00 B07/214
aVLBI0222c/33: Mon 7:30–10:00 B07/214
aVLBI0222c/34: Fri 11:10–13:40 B07/214
aVLBI0222c/35: Fri 8:30–11:00 B07/214
aVLBI0222c/36: Wed 10:10–12:40 B07/214
aVLBI0222c/37: Thu 8:30–11:00 B07/214
aVLBI0222c/38: Mon 14:00–16:30 B07/214
aVLBI0222c/39: Tue 9:00–11:30 B07/214

Prerequisites (in Czech)

aVLBI0121c Biology I - pract. && aVLBI0121s Biology I - seminar

Course Enrolment Limitations

The course is only offered to the students of the study fields the course is directly associated with.

fields of study / plans the course is directly associated with

• General Medicine (eng.) (programme LF, M-VL)
• General Medicine (programme LF, M-VL) (2)

Course objectives

After completion of the course student: operates light microscope; understands the basics of electron microscopy, genetic toxicology, gene engineering or the methods of karyotyping; is able to evaluate the risk of hereditary diseases in a patient on the basis of assigned family anamnesis of this disease; is able to propose and interpret elementary molecular screening methods for some hereditary, neoplastic or microbial diseases. Student is also able to apply this knowledge and skills in other subject, especially histology, pathology and human genetics.

Learning outcomes

After completion of the course student: operates light microscope; understands the basics of electron microscopy, genetic toxicology, gene engineering or the methods of karyotyping; is able to evaluate the risk of hereditary diseases in a patient on the basis of assigned family anamnesis of this disease; is able to propose and interpret elementary molecular screening methods for some hereditary, neoplastic or microbial diseases. Student is also able to apply this knowledge and skills in other subject, especially histology, pathology and human genetics.

Syllabus

• Week 1: Genetic disorders - gonosomal inheritance
• Week 2: Deviations from Mendelian genetics
• Week 3: Genetic prognosis and genetic counselling
• Week 4: Human population genetics
• Week 5: Control test 3 (knowledge from week 13 of the autumn semester to week 4 of the spring semester - lectures, seminar, practices)
• Week 6: Molecular diagnostics of cancer
• Week 7: Gene engineering
• Week 8: Molecular analysis of human genotype
• Week 9: Molecular diagnostics of human pathogenic bacteria
• Week 10: Restriction mapping of DNA
• Week 11: Genetic toxicology
• Week 12: Control test 4 (knowledge from week 5 to week 11 of the spring semester - lectures, practices)
• Week 13: substitution practices (groups not having dissections clashing with the class)
• Week 14: substitution practices (remaining groups)

Literature

required literature
• Protocols for practices are provided in electronic form in the Information System of the Masaryk University in the Study Materials of the course aVLBI0222c

Teaching methods

laboratory practice, class discussion

Assessment methods

Practical classes are mandatory.
Requirements for course completion: full attendance in the practices (1 absence, excused or unexcused, is allowed); all protocols completed (also for missed lessons) and checked and signed by appropriate teachers; successfully passed 2 written control tests during the semester (20 questions each, 4 possibilities, 1 answer correct, student need to reach at least 12 points out of 20 in each test). In case you do not pass one of the control tests and its re-sit, you have to pass the final test (so-called Credit test) based on knowledge of the entire semester lectures and practices. The test comprises of 20 questions: 10 test questions (multiple answers can be correct, negative marking is obtained for incorrect answers) + 10 given terms for written explanation. At least 10 points out of 20 are needed to pass.
In case of student’s late arrival to the practice or poor activity at the practice, the student is required to write an essay in the length of 2 pages on a given topic. Same for the case of 2nd and any additional absence in practices (excused or unexcused). Find the instructions for essay writing in the Course-related instructions in the IS, bring the essay printed to the teacher who specified the topic and be ready to answer the teacher's questions regarding the topic.
In case of 3 absences, (or more than 3 absences all excused by the Office for Studies within 5 days from the beginning of the absence and introduced to the Information System), it is addressed individually and course-unit credit is awarded only after the proof of the student's knowledge of the entire semester topics (Credit test, see above).
In case of 4 or more unexcused absences, course-unit credit is not awarded.

Language of instruction

English

Follow-Up Courses

• aVLBC0321p Biochemistry I - lecture
• aVLBC0321s Biochemistry I - seminar
• aVLHE0322c Histology and Embryology II - practice
• aVLHE0322p Histology and Embryology II - lecture

Further comments (probably available only in Czech)

Study Materials
The course is taught annually.

Teacher's information

https://is.muni.cz/auth/el/1411/jaro2017/aVLBI0222c/index.qwarp

aVLBI0222c Biology II - practice

Extent and Intensity

0/3. 2 credit(s). Type of Completion: z (credit).

Teacher(s)

Rakesh Aithal, Ph.D., M.Sc. (seminar tutor)
Mgr. Veronika Altmannová, Ph.D. (seminar tutor)
Mgr. Lukáš Bálek, Ph.D. (seminar tutor)
Mgr. Kateřina Cetkovská, Ph.D. (seminar tutor)
Ing. Lívia Eiselleová, Ph.D. (seminar tutor)
Mgr. Linda Grillová, Ph.D. (seminar tutor)
Mgr. Iva Gudernová (seminar tutor)
Mgr. Hana Hříbková, Ph.D. (seminar tutor)
Mgr. Šárka Jelínková, Ph.D. (seminar tutor)
Mgr. Aneta Kohutová, Ph.D. (seminar tutor)
Mgr. Žaneta Konečná, Ph.D. (seminar tutor)
Mgr. María Victoria Marini Palomeque, Ph.D. (seminar tutor)
Mgr. Jarmila Mlčoušková, Ph.D. (seminar tutor)
Mgr. Gabriela Páchniková (seminar tutor)
Mgr. Lenka Paštěková, Ph.D. (seminar tutor)
Mgr. Iva Pernicová, Ph.D. (seminar tutor)
MUDr. Martin Pešl, Ph.D. (seminar tutor)
Mgr. Jakub Pivnička (seminar tutor)
Mgr. Petra Pospíšilová, Ph.D. (seminar tutor)
Mgr. Vladimír Rotrekl, Ph.D. (seminar tutor)
Pounami Samadder, Ph.D. (seminar tutor)
Mgr. Alexandra Sisáková, Ph.D. (seminar tutor)
Mgr. Zuzana Slabá (seminar tutor)
prof. MUDr. Iva Slaninová, Ph.D. (seminar tutor)
RNDr. Kateřina Snopková, Ph.D. (seminar tutor)
RNDr. Mário Špírek, PhD. (seminar tutor)
Mgr. Barbora Štefanovie, Ph.D. (seminar tutor)
Georgios Valianatos, Ph.D. (seminar tutor)
Mgr. Tereza Váňová, Ph.D. (seminar tutor)
Mgr. Kateřina Vopěnková, Ph.D. (seminar tutor)
Jana Růžičková (assistant)
Mgr. Martina Vráblíková (assistant)

Guaranteed by

prof. Ing. Petr Dvořák, CSc.
Department of Biology – Theoretical Departments – Faculty of Medicine
Contact Person: Mgr. Kateřina Vopěnková, Ph.D.
Supplier department: Department of Biology – Theoretical Departments – Faculty of Medicine

Timetable of Seminar Groups

aVLBI0222c/30: No timetable has been entered into IS.
aVLBI0222c/31: No timetable has been entered into IS.
aVLBI0222c/32: No timetable has been entered into IS.
aVLBI0222c/33: No timetable has been entered into IS.
aVLBI0222c/34: No timetable has been entered into IS.
aVLBI0222c/35: No timetable has been entered into IS.
aVLBI0222c/36: No timetable has been entered into IS.
aVLBI0222c/37: No timetable has been entered into IS.
aVLBI0222c/38: No timetable has been entered into IS.
aVLBI0222c/39: No timetable has been entered into IS.

Prerequisites (in Czech)

aVLBI0121c Biology I - pract. && aVLBI0121s Biology I - seminar

Course Enrolment Limitations

The course is only offered to the students of the study fields the course is directly associated with.

fields of study / plans the course is directly associated with

• General Medicine (eng.) (programme LF, M-VL)
• General Medicine (programme LF, M-VL) (2)

Course objectives

After completion of the course student: operates light microscope; understands the basics of electron microscopy, genetic toxicology, gene engineering or the methods of karyotyping; is able to evaluate the risk of hereditary diseases in a patient on the basis of assigned family anamnesis of this disease; is able to propose and interpret elementary molecular screening methods for some hereditary, neoplastic or microbial diseases. Student is also able to apply this knowledge and skills in other subject, especially histology, pathology and human genetics.

Syllabus

• Week 1: Genetic disorders - gonosomal inheritance
• Week 2: Deviations from Mendelian genetics
• Week 3: Genetic prognosis and genetic counselling
• Week 4: Human population genetics
• Week 5: DNA cloning and gene engineering. Control test for knowledge from week 13 of the autumn semester to week 4 of the spring semester (practices and lectures)
• Week 6: Molecular analysis of human genotype
• Week 7: Molecular diagnostics of human pathogenic bacteria
• Week 8: Restriction mapping of DNA
• Week 9: Molecular diagnostics of cancer disease
• Week 10: Substitution practices
• Week 11: Analysis of protein binding to DNA
• Week 12: Substitution practices
• Week 13: Genetic toxicology (groups not having dissections clashing with the class). Control test for knowledge from week 5 to week 12 of the spring semester (practices and lectures)
• Week 14: Genetic toxicology (groups not having dissections clashing with the class). Control test for knowledge from week 5 to week 12 of the spring semester (practices and lectures)

Literature

required literature
• Protocols for practices are provided in electronic form in the Information System of the Masaryk University in the Study Materials of the course aVLBI0222c

Teaching methods

laboratory practice, class discussion

Assessment methods

Practical classes are mandatory.
Requirements for course completion: full attendance in the practical classes (1 absence, excused or unexcused, is allowed); all protocols completed (also for missed lessons) and checked and signed by appropriate teachers; successfully passed 2 written control tests during the semester (20 questions each, 4 possibilities, 1 answer correct, student need to reach at least 14 points out of 20 in each test). In case you do not pass one of the control tests and its re-sit, you have to pass the final test (so-called Credit test) based on knowledge of the entire semester. The test comprises of 20 questions: 10 test questions (multiple answers can be correct, negative marking is obtained for incorrect answers) + 10 given terms for written explanation. At least 14 points out of 20 are needed to pass.
In case of student’s late arrival to the practice, poor activity at the practice student is required to write an essay in the length of 2 pages on a given topic. Same for the case of 2nd and any additional absence in practices, excused or unexcused. Find the instructions for essay writing in the Course-related instructions in the IS, bring the essay printed to the teacher who specified the topic and be ready to answer the teacher's questions regarding the topic.
In case of 3 absences, (or more than 3 absences all excused by the Office for Studies within 5 days from the beginning of the absence and introduced into the Information System), it is addressed individually and credit is given only after the proof of the student's knowledge of the entire semester topics (so-called Credit test, see above).
In case of 4 or more unexcused absences, credit is not awarded.

Language of instruction

English

Further comments (probably available only in Czech)

Study Materials
The course is taught annually.

Teacher's information

https://is.muni.cz/auth/el/1411/jaro2016/aVLBI0222c/index.qwarp

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