BLKLK051p Liquorology - lecture

Faculty of Medicine
Autumn 2015
Extent and Intensity
0/0. 3 credit(s). Type of Completion: zk (examination).
Teacher(s)
MUDr. Zdeňka Čermáková, Ph.D. (lecturer)
doc. MUDr. Milan Dastych, CSc., MBA (lecturer)
Michaela Gregorovičová (assistant)
Guaranteed by
doc. MUDr. Milan Dastych, CSc., MBA
Department of Laboratory Methods – Departments of Non-medical Branches – Faculty of Medicine
Contact Person: Michaela Gregorovičová
Supplier department: Department of Laboratory Methods – Departments of Non-medical Branches – Faculty of Medicine
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
The goal of theoretical part considering the subject of laboratory diagnosis of neurological diseases is to become familier with the modern conception of cerebrospinal fluid analysis. Sensitive immunochemical methods improve to make diagnosis of inflammatory and degenerative damages of nervous system. It is neccesssary to provide information related to indications and above all interpretations of results of the particular methods considering clinical units. In the practical part students gain experience with executing particular methods in cerebrospinal fluid analysis at least within the range that the graduate is able to join the working team of laboratory dealing with diagnosis of neurological diseases.; A student will be able to do the following upon completing the course: Understand the medical meaning of biochemical and cytological findings in cerebrospinal fluid(CSF); Differentiate between the composition of cerebrospinal fluid and blood serum; Recognize possible discrepancies in biochemical and cytological findings; Explain the importance of following recommended preanalytical procedures;
Syllabus
  • Preanalytical stage ; Total protein; Glukose, lactate ; Albumin, Q albumin (blood-CSF barrier); Disturbances of the blood-CSF barier; Detection of intrathecal immunoglobulin synthesis ; CSF/serum ratio diagram (Oligoclonal bands, isoelectric focusing); Paraneoplastic antibodies (anti-Hu, anti-Ri, anti- Yo); CSF cells – quantitative, qualitative; Acute meningitis, tuberculous meningitis, neuroborreliosis, brain tumors, brain infarction, polyneuropathies, HIV encephalitis, chronic inflammatory processes, multiple sclerosis; Markers of tissue destruction;
Literature
  • DASTYCH, Milan, Zdeňka ČERMÁKOVÁ, Pavel ŠTOURAČ, Alena ŠEVČÍKOVÁ, Iva KOCMANOVÁ and Svatava SNOPKOVÁ. Mikroskopický nález kryptokoka v mozkomíšním moku jako první příznak rozvinutého stadia AIDS: kazuistika. (Microskopis detection of Cryptococcus in the cerebrospinal fluid as the first symptom of the advanced stage of AIDS - a case study.). Česká a slovenská neurologie a neurochirurgie. Brno: Medica Healthworld, 2008, 71/104, No 1, p. 93-96. ISSN 1802-4041. info
Teaching methods
a lecture with the use of audiovisual teaching aids (pp-presentations, commented videos) including interactive input
Assessment methods
a final oral examination with questions from the general and specialized portions of the course;
Language of instruction
Czech
Further comments (probably available only in Czech)
Study Materials
Information on the extent and intensity of the course: 10 h/semestr.
The course is also listed under the following terms Autumn 2011, Autumn 2012, Autumn 2013, Autumn 2014, Autumn 2016, Autumn 2017, autumn 2018, autumn 2019.
  • Enrolment Statistics (Autumn 2015, recent)
  • Permalink: https://is.muni.cz/course/med/autumn2015/BLKLK051p