FDRFa_FAF Rational Pharmacotherapy

Faculty of Pharmacy
Autumn 2025
Extent and Intensity
2/0/0. 5 credit(s). Type of Completion: zk (examination).
In-person direct teaching
Teacher(s)
PharmDr. Bc. Hana Kotolová, Ph.D. (lecturer)
Guaranteed by
PharmDr. Bc. Hana Kotolová, Ph.D.
Faculty of Pharmacy
Supplier department: Department of Pharmacology and Toxicology – Departments – Faculty of Pharmacy
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
The aim of the course is to provide students with an interdisciplinary perspective, integrating knowledge of experimental pharmacology with clinical and paraclinical disciplines with the aim of studying and using objective methods to evaluate the effectiveness and safety of medicines, and factors influencing rational pharmacotherapy.
Learning outcomes
The student will gain a more detailed view of the clinical use of medicines and rational and individualized pharmacotherapy.
Syllabus
General introduction, basic terminology, therapeutic monitoring of drugs
Basic clinical values examined in clinical biochemistry
Pharmacodynamic and pharmacokinetic drug interactions
Addictions to medical drugs.
Clinical manifestations of adverse drug reactions, potentially inappropriate medication in old age
Pharmacotherapy in pregnancy and lactation
Pharmacotherapy of psychotic disorders
Pharmacotherapy of depressions, anxiety and insomnia
Pharmacotherapy of selected CNS diseases (Parkinson?s disease, multiple sclerosis Alzheimer?s disease, vascular dementia).
Pharmacotherapy of allergic diseases, bronchial asthma.
Chronic obstructive pulmonary disease, infectious diseases of the air passages
Metabolic syndrome, obesity, disorders of lipid metabolism.
Pharmacotherapy in diabetes mellitus, late complications of DM.
Pharmacotherapy in cardiology (ischemic heart disease, heart failure, heart rhythm disorders, arterial hypertension )
Pharmacotherapy of digestive tract diseases (disorders of oesophagus, stomach, duodenum, liver disorders)
Pharmacotherapy v hematology (anemia, hemostasis disorders )
Pharmacotherapy v endocrinology (thyroid disorders)
Pharmacotherapy osteopathy
Pharmacotherapy in urology (benign prostate hyperplasia, erectile dysfunction, incontinence)

Literature
    required literature
  • RITTER, James; R. J. FLOWER; Graeme HENDERSON; Yoon Kong LOKE; David J. MACEWAN; Emma S. J. ROBINSON and James FULLERTON. Rang & Dale's pharmacology / James M. Ritter, Rod Flower, Graeme Henderson, Yoon Kong Loke, David MacEvan, Emma Robinson, James Fullerton. Tenth edition. London: Elsevier, 2024, xvii, 850. ISBN 9780323873963. info
  • BROWN, M. J.; Pankaj SHARMA; Fraz A. MIR and P. N. BENNETT. Clinical pharmacology. Twelfth edition. Edinburgh: Elsevier, 2019, 1 online. ISBN 9780702073304. URL info
  • Markova farmakoterapie vnitřních nemocí. Edited by Josef Marek - Michal Vrablík. 5., zcela přepracované a d. Praha: Grada, 2019, xxiv, 868. ISBN 9788024750781. info
  • Farmakologie. Edited by Jan Švihovec - Jan Bultas - Pavel Anzenbacher - Jaroslav Chládek - J. 1. vydání. Praha: Grada Publishing, 2018, xix, 962. ISBN 9788024755588. info
    recommended literature
  • Martina Vašáková a kolektiv. Moderní farmakoterapie v pneumologii. Maxdorf. ISBN 978-80-7345-506-4. info
  • BENEŠ, Jiří. Antibiotika : systematika, vlastnosti, použití. 1. vydání. Praha: Grada Publishing, 2018, 598 stran. ISBN 9788027106363. info
  • Basic & clinical pharmacology. Edited by Bertram G. Katzung. Fourteenth Edition. New York: McGraw-Hill, 2018, xi, 1250. ISBN 9781259641152. info
  • Mohr P. Klinická psychofarmakologie. 2017. info
  • Štětkářová I. a kol. Moderní farmakoterapie v neurologii. Maxdorf, 2017. ISBN 978-80-7345-5. info
  • Stockley. Drug Interactions. Pharmaceutical Press, 2016. ISBN 978 0 85711 270 5. info
  • PERLÍK, František and Ondřej SLANAŘ. Individualizace farmakoterapie. Vydání 1. Praha: Stanislav Juhaňák - Triton, 2016, 159 stran. ISBN 9788073876364. info
  • Libor Zámečník, Petr Macek. Moderní farmakoterapie v urologii. Maxdorf, 2012. ISBN 978-80-7345-276-6. info
Teaching methods
individual consultation, study of professional literature
Assessment methods
Oral exam
Language of instruction
English
The course is also listed under the following terms Spring 2025, Spring 2026.
  • Enrolment Statistics (Autumn 2025, recent)
  • Permalink: https://is.muni.cz/course/pharm/autumn2025/FDRFa_FAF